SIRT1, an antiinflammatory and antiaging protein, is decreased in lungs of patients with chronic obstructive pulmonary disease S Rajendrasozhan, SR Yang, VL Kinnula, I Rahman American journal of respiratory and critical care medicine 177 (8), 861-870, 2008 | 605 | 2008 |
Resveratrol induces glutathione synthesis by activation of Nrf2 and protects against cigarette smoke-mediated oxidative stress in human lung epithelial cells A Kode, S Rajendrasozhan, S Caito, SR Yang, IL Megson, I Rahman American Journal of Physiology-Lung Cellular and Molecular Physiology 294 (3 …, 2008 | 556 | 2008 |
SIRT1 protects against emphysema via FOXO3-mediated reduction of premature senescence in mice H Yao, S Chung, J Hwang, S Rajendrasozhan, IK Sundar, DA Dean, ... The Journal of clinical investigation 122 (6), 2032-2045, 2012 | 387 | 2012 |
SIRT1 is a redox-sensitive deacetylase that is post-translationally modified by oxidants and carbonyl stress S Caito, S Rajendrasozhan, S Cook, S Chung, H Yao, AE Friedman, ... The FASEB Journal 24 (9), 3145, 2010 | 340 | 2010 |
Protective effect of ursolic acid on ethanol-mediated experimental liver damage in rats R Saravanan, P Viswanathan, KV Pugalendi Life sciences 78 (7), 713-718, 2006 | 272 | 2006 |
Curcumin restores corticosteroid function in monocytes exposed to oxidants by maintaining HDAC2 KK Meja, S Rajendrasozhan, D Adenuga, SK Biswas, IK Sundar, ... American journal of respiratory cell and molecular biology 39 (3), 312-323, 2008 | 240 | 2008 |
Deacetylases and NF-κB in Redox Regulation of Cigarette Smoke-Induced Lung Inflammation: Epigenetics in Pathogenesis of COPD S Rajendrasozhan, SR Yang, I Edirisinghe, H Yao, D Adenuga, I Rahman Antioxidants & redox signaling 10 (4), 799-812, 2008 | 207 | 2008 |
Cigarette smoke-mediated inflammatory and oxidative responses are strain-dependent in mice H Yao, I Edirisinghe, S Rajendrasozhan, SR Yang, S Caito, D Adenuga, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 294 (6 …, 2008 | 176 | 2008 |
Redox regulation of lung inflammation: role of NADPH oxidase and NF-κB signalling H Yao, SR Yang, A Kode, S Rajendrasozhan, S Caito, D Adenuga, ... Biochemical Society Transactions 35 (5), 1151-1155, 2007 | 170 | 2007 |
FOXO3 deficiency leads to increased susceptibility to cigarette smoke-induced inflammation, airspace enlargement, and chronic obstructive pulmonary disease J Hwang, S Rajendrasozhan, H Yao, S Chung, IK Sundar, HL Huyck, ... The Journal of Immunology 187 (2), 987-998, 2011 | 165 | 2011 |
Effect of Piper betle leaf extract on alcoholic toxicity in the rat brain R Saravanan, N Rajendra Prasad, KV Pugalendi Journal of Medicinal Food 6 (3), 261-265, 2003 | 129 | 2003 |
Disruption of p21 attenuates lung inflammation induced by cigarette smoke, LPS, and fMLP in mice H Yao, SR Yang, I Edirisinghe, S Rajendrasozhan, S Caito, D Adenuga, ... American journal of respiratory cell and molecular biology 39 (1), 7-18, 2008 | 124 | 2008 |
Genetic ablation of NADPH oxidase enhances susceptibility to cigarette smoke-induced lung inflammation and emphysema in mice H Yao, I Edirisinghe, SR Yang, S Rajendrasozhan, A Kode, S Caito, ... The American journal of pathology 172 (5), 1222-1237, 2008 | 120 | 2008 |
VEGFR-2 inhibition augments cigarette smoke-induced oxidative stress and inflammatory responses leading to endothelial dysfunction I Edirisinghe, SR Yang, H Yao, S Rajendrasozhan, S Caito, D Adenuga, ... FASEB journal: official publication of the Federation of American Societies …, 2008 | 117 | 2008 |
Impact of ursolic acid on chronic ethanol-induced oxidative stress in the rat heart R Saravanan, KV Pugalendi Pharmacological Reports 58 (1), 41-47, 2006 | 116 | 2006 |
IKKα causes chromatin modification on pro-inflammatory genes by cigarette smoke in mouse lung SR Yang, S Valvo, H Yao, A Kode, S Rajendrasozhan, I Edirisinghe, ... American journal of respiratory cell and molecular biology 38 (6), 689-698, 2008 | 113 | 2008 |
Influence of sesame oil on blood glucose, lipid peroxidation and antioxidants' status in streptozotocin diabetic rats B Ramesh, R Saravanan, KV Pugalendi Journal of Medicinal Food 8 (3), 377-381, 2005 | 109 | 2005 |
Current perspectives on role of chromatin modifications and deacetylases in lung inflammation in COPD S Rajendrasozhan, H Yao, I Rahman COPD: Journal of Chronic Obstructive Pulmonary Disease 6 (4), 291-297, 2009 | 101 | 2009 |
Influence of Piper betle on hepatic marker enzymes and tissue antioxidant status in ethanol-treated Wistar rats R Saravanan, A Prakasam, B Ramesh, KV Pugalendi Journal of Medicinal Food 5 (4), 197-204, 2002 | 77 | 2002 |
Targeted disruption of NF-κB1 (p50) augments cigarette smoke-induced lung inflammation and emphysema in mice: a critical role of p50 in chromatin remodeling S Rajendrasozhan, S Chung, IK Sundar, H Yao, I Rahman American Journal of Physiology-Lung Cellular and Molecular Physiology 298 (2 …, 2010 | 75 | 2010 |