Metalloproteins Containing Cytochrome, Iron–Sulfur, or Copper Redox Centers J Liu, S Chakraborty, P Hosseinzadeh, Y Yu, S Tian, I Petrik, A Bhagi, ... Chemical Reviews 114 (8), 4366-4469, 2014 | 916 | 2014 |
Comprehensive computational design of ordered peptide macrocycles P Hosseinzadeh, G Bhardwaj, VK Mulligan, MD Shortridge, TW Craven, ... Science 358 (6369), 1461-1466, 2017 | 201 | 2017 |
Design and fine-tuning redox potentials of metalloproteins involved in electron transfer in bioenergetics P Hosseinzadeh, Y Lu Biochimica et Biophysica Acta (BBA)-Bioenergetics 1857 (5), 557-581, 2016 | 189 | 2016 |
A designed heme-[4Fe-4S] metalloenzyme catalyzes sulfite reduction like the native enzyme EN Mirts, ID Petrik, P Hosseinzadeh, MJ Nilges, Y Lu Science 361 (6407), 1098-1101, 2018 | 136 | 2018 |
Design of a single protein that spans the entire 2-V range of physiological redox potentials P Hosseinzadeh, NM Marshall, KN Chacón, Y Yu, MJ Nilges, SY New, ... Proceedings of the National Academy of Sciences 113 (2), 262-267, 2016 | 115 | 2016 |
Accurate de novo design of membrane-traversing macrocycles G Bhardwaj, J O’Connor, S Rettie, YH Huang, TA Ramelot, VK Mulligan, ... Cell 185 (19), 3520-3532. e26, 2022 | 106 | 2022 |
Biochemical and biophysical understanding of metal ion selectivity of dnazymes K Hwang, P Hosseinzadeh, Y Lu Inorganica Chimica Acta 452, 12-24, 2016 | 94 | 2016 |
Defining the role of tyrosine and rational tuning of oxidase activity by genetic incorporation of unnatural tyrosine analogs Y Yu, X Lv, J Li, Q Zhou, C Cui, P Hosseinzadeh, A Mukherjee, MJ Nilges, ... Journal of the American Chemical Society 137 (14), 4594-4597, 2015 | 94 | 2015 |
Anchor extension: a structure-guided approach to design cyclic peptides targeting enzyme active sites P Hosseinzadeh, PR Watson, TW Craven, X Li, S Rettie, F Pardo-Avila, ... Nature Communications 12 (1), 3384, 2021 | 62 | 2021 |
Computationally designed peptide macrocycle inhibitors of New Delhi metallo-β-lactamase 1 VK Mulligan, S Workman, T Sun, S Rettie, X Li, LJ Worrall, TW Craven, ... Proceedings of the National Academy of Sciences 118 (12), e2012800118, 2021 | 58 | 2021 |
Heme redox potentials hold the key to reactivity differences between nitric oxide reductase and heme-copper oxidase A Bhagi-Damodaran, JH Reed, Q Zhu, Y Shi, P Hosseinzadeh, ... Proceedings of the National Academy of Sciences 115 (24), 6195-6200, 2018 | 47 | 2018 |
Reversible S-Nitrosylation in an Engineered Azurin S Tian, J Liu, R Cowley, P Hosseinzadeh, N Marshall, Y Yu, H Robinson, ... Nature Chemistry, 2016 | 41 | 2016 |
Overcoming Near-Cognate Suppression in a Release Factor 1-Deficient Host with an Improved Nitro-Tyrosine tRNA Synthetase JN Beyer, P Hosseinzadeh, I Gottfried-Lee, EM Van Fossen, P Zhu, ... Journal of molecular biology 432 (16), 4690-4704, 2020 | 34 | 2020 |
Long-range electron transfer in engineered azurins exhibits Marcus inverted region behavior O Farver, P Hosseinzadeh, NM Marshall, S Wherland, Y Lu, I Pecht The journal of physical chemistry letters 6 (1), 100-105, 2015 | 34 | 2015 |
Direct EPR Observation of a Tyrosyl Radical in a Functional Oxidase Model in Myoglobin during both H2O2 and O2 Reactions Y Yu, A Mukherjee, MJ Nilges, P Hosseinzadeh, KD Miner, Y Lu Journal of the American Chemical Society 136 (4), 1174-1177, 2014 | 33 | 2014 |
A Purple Cupredoxin from Nitrosopumilus maritimus Containing a Mononuclear Type 1 Copper Center with an Open Binding Site P Hosseinzadeh, S Tian, NM Marshall, J Hemp, T Mullen, MJ Nilges, ... Journal of the American Chemical Society 138 (20), 6324-6327, 2016 | 30 | 2016 |
Enhancing Mn(II)-Binding and Manganese Peroxidase Activity in a Designed Cytochrome c Peroxidase through Fine-Tuning Secondary-Sphere Interactions P Hosseinzadeh, EN Mirts, TD Pfister, YG Gao, C Mayne, H Robinson, ... Biochemistry 55 (10), 1494-1502, 2016 | 27 | 2016 |
Identifying the elusive sites of tyrosyl radicals in cytochrome c peroxidase: implications for oxidation of substrates bound at a site remote from the heme KD Miner, TD Pfister, P Hosseinzadeh, N Karaduman, LJ Donald, ... Biochemistry 53 (23), 3781-3789, 2014 | 26 | 2014 |
Stopped-Flow Studies of the Reduction of the Copper Centers Suggest a Bifurcated Electron Transfer Pathway in Peptidylglycine Monooxygenase S Chauhan, P Hosseinzadeh, Y Lu, NJ Blackburn Biochemistry 55 (13), 2008-2021, 2016 | 20 | 2016 |
Design of protein segments and peptides for binding to protein targets S Gupta, N Azadvari, P Hosseinzadeh BioDesign Research 2022, 2022 | 19 | 2022 |