Peripheral T cell expansion predicts tumour infiltration and clinical response TD Wu, S Madireddi, PE de Almeida, R Banchereau, YJJ Chen, AS Chitre, ... Nature 579 (7798), 274-278, 2020 | 615 | 2020 |
Cutting edge: Mechanisms of IL-2–dependent maintenance of functional regulatory T cells L Barron, H Dooms, KK Hoyer, W Kuswanto, J Hofmann, WE O’Gorman, ... The Journal of Immunology 185 (11), 6426-6430, 2010 | 279 | 2010 |
Rational strain selection and engineering creates a broad-spectrum, systemically effective oncolytic poxvirus, JX-963 SH Thorne, THH Hwang, WE O’Gorman, DL Bartlett, S Sei, F Kanji, ... The Journal of clinical investigation 117 (11), 3350-3358, 2007 | 271 | 2007 |
Intratumoral plasma cells predict outcomes to PD-L1 blockade in non-small cell lung cancer NS Patil, BY Nabet, S Müller, H Koeppen, W Zou, J Giltnane, A Au-Yeung, ... Cancer cell 40 (3), 289-300. e4, 2022 | 263 | 2022 |
Mechanistic convergence of the TIGIT and PD-1 inhibitory pathways necessitates co-blockade to optimize anti-tumor CD8+ T cell responses KL Banta, X Xu, AS Chitre, A Au-Yeung, C Takahashi, WE O’Gorman, ... Immunity 55 (3), 512-526. e9, 2022 | 229 | 2022 |
Mammalian target of rapamycin controls dendritic cell development downstream of Flt3 ligand signaling T Sathaliyawala, WE O'Gorman, M Greter, M Bogunovic, V Konjufca, ... Immunity 33 (4), 597-606, 2010 | 210 | 2010 |
Dynamic CD8+ T cell responses to cancer immunotherapy in human regional lymph nodes are disrupted in metastatic lymph nodes MK Rahim, TLH Okholm, KB Jones, EE McCarthy, CC Liu, JL Yee, ... Cell 186 (6), 1127-1143. e18, 2023 | 206 | 2023 |
The initial phase of an immune response functions to activate regulatory T cells WE O'Gorman, H Dooms, SH Thorne, WF Kuswanto, EF Simonds, ... The Journal of Immunology 183 (1), 332-339, 2009 | 191 | 2009 |
Ulcerative colitis is characterized by a plasmablast-skewed humoral response associated with disease activity M Uzzan, JC Martin, L Mesin, AE Livanos, T Castro-Dopico, R Huang, ... Nature medicine 28 (4), 766-779, 2022 | 132 | 2022 |
Intratumoral CD103+ CD8+ T cells predict response to PD-L1 blockade R Banchereau, AS Chitre, A Scherl, TD Wu, NS Patil, P de Almeida, ... Journal for ImmunoTherapy of Cancer 9 (4), 2021 | 114 | 2021 |
Duration of antigen receptor signaling determines T-cell tolerance or activation SD Katzman, WE O'Gorman, AV Villarino, E Gallo, RS Friedman, ... Proceedings of the National Academy of Sciences 107 (42), 18085-18090, 2010 | 91 | 2010 |
Mass cytometry panel optimization through the designed distribution of signal interference C Takahashi, A Au‐Yeung, F Fuh, T Ramirez‐Montagut, C Bolen, ... Cytometry Part A 91 (1), 39-47, 2017 | 87 | 2017 |
Single-cell systems-level analysis of human Toll-like receptor activation defines a chemokine signature in patients with systemic lupus erythematosus WE O'Gorman, EWY Hsieh, ES Savig, PF Gherardini, JD Hernandez, ... Journal of Allergy and Clinical Immunology 136 (5), 1326-1336, 2015 | 86 | 2015 |
Late-differentiated effector neoantigen-specific CD8+ T cells are enriched in peripheral blood of non-small cell lung carcinoma patients responding to atezolizumab treatment M Fehlings, S Jhunjhunwala, M Kowanetz, WE O’Gorman, PS Hegde, ... Journal for immunotherapy of cancer 7, 1-15, 2019 | 84 | 2019 |
The potential functions of primary microRNAs in target recognition and repression RD Trujillo, SB Yue, Y Tang, WE O'gorman, CZ Chen The EMBO journal 29 (19), 3272-3285, 2010 | 80 | 2010 |
Mass cytometry identifies a distinct monocyte cytokine signature shared by clinically heterogeneous pediatric SLE patients WE O'Gorman, DS Kong, IM Balboni, P Rudra, CR Bolen, D Ghosh, ... Journal of autoimmunity 81, 74-89, 2017 | 70 | 2017 |
Quantitative comparison of conventional and t-SNE-guided gating analyses S Toghi Eshghi, A Au-Yeung, C Takahashi, CR Bolen, MN Nyachienga, ... Frontiers in immunology 10, 1194, 2019 | 66 | 2019 |
The Split Virus Influenza Vaccine rapidly activates immune cells through Fcγ receptors WE O’Gorman, H Huang, YL Wei, KL Davis, MD Leipold, SC Bendall, ... Vaccine 32 (45), 5989-5997, 2014 | 44 | 2014 |
Alternate mechanisms of initial pattern recognition drive differential immune responses to related poxviruses WE O'Gorman, P Sampath, EF Simonds, R Sikorski, M O'Malley, ... Cell host & microbe 8 (2), 174-185, 2010 | 41 | 2010 |
Distinct regulation of integrin-dependent T cell conjugate formation and NF-κB activation by the adapter protein ADAP BJ Burbach, R Srivastava, RB Medeiros, WE O'Gorman, EJ Peterson, ... The Journal of Immunology 181 (7), 4840-4851, 2008 | 40 | 2008 |