| The tumour microenvironment after radiotherapy: mechanisms of resistance and recurrence HE Barker, JTE Paget, AA Khan, KJ Harrington Nature Reviews Cancer 15 (7), 409-425, 2015 | 2030 | 2015 |
| Gata-3 is an essential regulator of mammary-gland morphogenesis and luminal-cell differentiation ML Asselin-Labat, KD Sutherland, H Barker, R Thomas, M Shackleton, ... Nature cell biology 9 (2), 201-209, 2007 | 989 | 2007 |
| The rationale for targeting the LOX family in cancer HE Barker, TR Cox, JT Erler Nature Reviews Cancer 12 (8), 540-552, 2012 | 647 | 2012 |
| LOX-mediated collagen crosslinking is responsible for fibrosis-enhanced metastasis TR Cox, D Bird, AM Baker, HE Barker, MWY Ho, G Lang, JT Erler Cancer research 73 (6), 1721-1732, 2013 | 618 | 2013 |
| Secondary Somatic Mutations Restoring RAD51C and RAD51D Associated with Acquired Resistance to the PARP Inhibitor Rucaparib in High-Grade Ovarian … O Kondrashova, M Nguyen, K Shield-Artin, AV Tinker, NNH Teng, ... Cancer discovery 7 (9), 984-998, 2017 | 404 | 2017 |
| LOXL2-mediated matrix remodeling in metastasis and mammary gland involution HE Barker, J Chang, TR Cox, G Lang, D Bird, M Nicolau, HR Evans, ... Cancer research 71 (5), 1561-1572, 2011 | 336 | 2011 |
| Tumor-secreted LOXL2 activates fibroblasts through FAK signaling HE Barker, D Bird, G Lang, JT Erler Molecular Cancer Research 11 (11), 1425-1436, 2013 | 133 | 2013 |
| Radiosensitization by the ATR inhibitor AZD6738 through generation of acentric micronuclei MT Dillon, HE Barker, M Pedersen, H Hafsi, SA Bhide, KL Newbold, ... Molecular cancer therapeutics 16 (1), 25-34, 2017 | 119 | 2017 |
| CHK1 Inhibition Radiosensitizes Head and Neck Cancers to Paclitaxel-Based Chemoradiotherapy HE Barker, R Patel, M McLaughlin, U Schick, S Zaidi, CM Nutting, ... Molecular Cancer Therapeutics 15 (9), 2042-2054, 2016 | 57 | 2016 |
| Combined ATR and DNA-PK inhibition radiosensitizes tumor cells independently of their p53 status H Hafsi, MT Dillon, HE Barker, JN Kyula, U Schick, JT Paget, HG Smith, ... Frontiers in oncology 8, 245, 2018 | 50 | 2018 |
| Trametinib radiosensitises RAS-and BRAF-mutated melanoma by perturbing cell cycle and inducing senescence U Schick, J Kyula, H Barker, R Patel, S Zaidi, C Gregory, H Hafsi, ... Radiotherapy and Oncology 117 (2), 364-375, 2015 | 48 | 2015 |
| Three‐dimensional modelling identifies novel genetic dependencies associated with breast cancer progression in the isogenic MCF10 model SL Maguire, B Peck, PT Wai, J Campbell, H Barker, A Gulati, F Daley, ... The Journal of Pathology 240 (3), 315-328, 2016 | 45 | 2016 |
| Deaf-1 regulates epithelial cell proliferation and side-branching in the mammary gland HE Barker, GK Smyth, J Wettenhall, TA Ward, ML Bath, GJ Lindeman, ... BMC Developmental Biology 8, 1-14, 2008 | 43 | 2008 |
| HSP90 inhibition sensitizes head and neck cancer to platin-based chemoradiotherapy by modulation of the DNA damage response resulting in chromosomal fragmentation M McLaughlin, HE Barker, AA Khan, M Pedersen, M Dillon, DC Mansfield, ... BMC cancer 17, 1-13, 2017 | 41 | 2017 |
| LOXL2 induces aberrant acinar morphogenesis via ErbB2 signaling J Chang, MM Nicolau, TR Cox, D Wetterskog, JWM Martens, H E Barker, ... Breast Cancer Research 15, 1-18, 2013 | 39 | 2013 |
| Identification of hypoxia-regulated proteins using MALDI-mass spectrometry imaging combined with quantitative proteomics MC Djidja, J Chang, A Hadjiprocopis, F Schmich, J Sinclair, M Mršnik, ... Journal of proteome research 13 (5), 2297-2313, 2014 | 37 | 2014 |
| The potential for LOXL2 as a target for future cancer treatment HE Barker, JT Erler Future Oncology 7 (6), 707-710, 2011 | 28 | 2011 |
| An orally bioavailable Chk1 inhibitor, CCT244747, sensitizes bladder and head and neck cancer cell lines to radiation R Patel, HE Barker, J Kyula, M McLaughlin, MT Dillon, U Schick, H Hafsi, ... Radiotherapy and Oncology 122 (3), 470-475, 2017 | 23 | 2017 |
| SF3B1 hotspot mutations confer sensitivity to PARP inhibition by eliciting a defective replication stress response P Bland, H Saville, PT Wai, L Curnow, G Muirhead, J Nieminuszczy, ... Nature Genetics 55 (8), 1311-1323, 2023 | 22 | 2023 |
| Structural basis of the interaction of the breast cancer oncogene LMO4 with the tumour suppressor CtIP/RBBP8 PH Stokes, CW Liew, AH Kwan, P Foo, HE Barker, A Djamirze, V O'Reilly, ... Journal of molecular biology 425 (7), 1101-1110, 2013 | 18 | 2013 |