Anatomical, physiological and metabolic changes with gestational age during normal pregnancy: a database for parameters required in physiologically based pharmacokinetic modelling K Abduljalil, P Furness, TN Johnson, A Rostami-Hodjegan, H Soltani Clinical pharmacokinetics 51, 365-396, 2012 | 413 | 2012 |
Does age affect gastric emptying time? A model‐based meta‐analysis of data from premature neonates through to adults JJ Bonner, P Vajjah, K Abduljalil, M Jamei, A Rostami‐Hodjegan, ... Biopharmaceutics & drug disposition 36 (4), 245-257, 2015 | 158 | 2015 |
Deciding on success criteria for predictability of pharmacokinetic parameters from in vitro studies: an analysis based on in vivo observations K Abduljalil, T Cain, H Humphries, A Rostami-Hodjegan Drug Metabolism and Disposition 42 (9), 1478-1484, 2014 | 151 | 2014 |
A pregnancy physiologically based pharmacokinetic (p‐PBPK) model for disposition of drugs metabolized by CYP1A2, CYP2D6 and CYP3A4 L Gaohua, K Abduljalil, M Jamei, TN Johnson, A Rostami‐Hodjegan British journal of clinical pharmacology 74 (5), 873-885, 2012 | 137 | 2012 |
A re-evaluation and validation of ontogeny functions for cytochrome P450 1A2 and 3A4 based on in vivo data F Salem, TN Johnson, K Abduljalil, GT Tucker, A Rostami-Hodjegan Clinical pharmacokinetics 53, 625-636, 2014 | 128 | 2014 |
Factors influencing pharmacokinetics of prophylactic posaconazole in patients undergoing allogeneic stem cell transplantation V Kohl, C Muller, OA Cornely, K Abduljalil, U Fuhr, JJ Vehreschild, ... Antimicrobial agents and chemotherapy 54 (1), 207-212, 2010 | 88 | 2010 |
Changes in individual drug-independent system parameters during virtual paediatric pharmacokinetic trials: introducing time-varying physiology into a paediatric PBPK model K Abduljalil, M Jamei, A Rostami-Hodjegan, TN Johnson The AAPS journal 16, 568-576, 2014 | 86 | 2014 |
Application of a Physiologically Based Pharmacokinetic Model to Predict OATP1B1‐Related Variability in Pharmacodynamics of Rosuvastatin RH Rose, S Neuhoff, K Abduljalil, M Chetty, A Rostami‐Hodjegan, ... CPT: pharmacometrics & systems pharmacology 3 (7), 1-9, 2014 | 83 | 2014 |
Drug dosing in pregnant women: challenges and opportunities in using physiologically based pharmacokinetic modeling and simulations AB Ke, R Greupink, K Abduljalil CPT: pharmacometrics & systems pharmacology 7 (2), 103-110, 2018 | 75 | 2018 |
Assessment of Activity Levels for CYP2D6*1, CYP2D6*2, and CYP2D6*41 Genes by Population Pharmacokinetics of Dextromethorphan K Abduljalil, D Frank, A Gaedigk, T Klaassen, D Tomalik‐Scharte, A Jetter, ... Clinical Pharmacology & Therapeutics 88 (5), 643-651, 2010 | 69 | 2010 |
Applications of linking PBPK and PD models to predict the impact of genotypic variability, formulation differences, differences in target binding capacity and target site drug … M Chetty, RH Rose, K Abduljalil, N Patel, G Lu, T Cain, M Jamei, ... Frontiers in pharmacology 5, 258, 2014 | 65 | 2014 |
Drug dosing during pregnancy—opportunities for physiologically based pharmacokinetic models K Abduljalil, RKS Badhan Journal of pharmacokinetics and pharmacodynamics 47 (4), 319-340, 2020 | 60 | 2020 |
Physiologically-based pharmacokinetic (PBPK) models for assessing the kinetics of xenobiotics during pregnancy: achievements and shortcomings G Lu, K Abduljalil, M Jamei, T N. Johnson, H Soltani, A Rostami-Hodjegan Current drug metabolism 13 (6), 695-720, 2012 | 57 | 2012 |
Prediction of maternal pharmacokinetics using physiologically based pharmacokinetic models: assessing the impact of the longitudinal changes in the activity of CYP1A2, CYP2D6 … K Abduljalil, A Pansari, M Jamei Journal of pharmacokinetics and pharmacodynamics 47 (4), 361-383, 2020 | 51 | 2020 |
A preterm physiologically based pharmacokinetic model. Part I: physiological parameters and model building K Abduljalil, X Pan, A Pansari, M Jamei, TN Johnson Clinical Pharmacokinetics 59, 485-500, 2020 | 47 | 2020 |
Preterm physiologically based pharmacokinetic model. Part II: applications of the model to predict drug pharmacokinetics in the preterm population K Abduljalil, X Pan, A Pansari, M Jamei, TN Johnson Clinical Pharmacokinetics 59, 501-518, 2020 | 45 | 2020 |
Prediction of drug concentrations in milk during breastfeeding, integrating predictive algorithms within a physiologically‐based pharmacokinetic model K Abduljalil, A Pansari, J Ning, M Jamei CPT: pharmacometrics & systems pharmacology 10 (8), 878-889, 2021 | 44 | 2021 |
Fetal physiologically based pharmacokinetic models: systems information on the growth and composition of fetal organs K Abduljalil, M Jamei, TN Johnson Clinical Pharmacokinetics 58, 235-262, 2019 | 43 | 2019 |
Considering age variation when coining drugs as high versus low hepatic extraction ratio F Salem, K Abduljalil, Y Kamiyama, A Rostami-Hodjegan Drug Metabolism and Disposition 44 (7), 1099-1102, 2016 | 41 | 2016 |
Assessment of Maternal and Fetal Dolutegravir Exposure by Integrating Ex Vivo Placental Perfusion Data and Physiologically‐Based Pharmacokinetic Modeling JJM Freriksen, S Schalkwijk, AP Colbers, K Abduljalil, FGM Russel, ... Clinical Pharmacology & Therapeutics 107 (6), 1352-1361, 2020 | 37 | 2020 |