A novel class of anticancer compounds targets the actin cytoskeleton in tumor cells JR Stehn, NK Haass, T Bonello, M Desouza, G Kottyan, H Treutlein, ... Cancer research 73 (16), 5169-5182, 2013 | 206 | 2013 |
Scribble: A master scaffold in polarity, adhesion, synaptogenesis, and proliferation TT Bonello, M Peifer Journal of Cell Biology 218 (3), 742-756, 2019 | 129 | 2019 |
Rap1 acts via multiple mechanisms to position Canoe and adherens junctions and mediate apical-basal polarity establishment TT Bonello, KZ Perez-Vale, KD Sumigray, M Peifer Development 145 (2), dev157941, 2018 | 74 | 2018 |
New approaches to targeting the actin cytoskeleton for chemotherapy TT Bonello, JR Stehn, PW Gunning Future medicinal chemistry 1 (7), 1311-1331, 2009 | 72 | 2009 |
Supramolecular assembly of the beta-catenin destruction complex and the effect of Wnt signaling on its localization, molecular size, and activity in vivo KN Schaefer, TT Bonello, S Zhang, CE Williams, DM Roberts, DJ McKay, ... PLoS Genetics 14 (4), e1007339, 2018 | 67 | 2018 |
The impact of tropomyosins on actin filament assembly is isoform specific M Janco, TT Bonello, A Byun, ACF Coster, H Lebhar, I Dedova, ... Bioarchitecture 6 (4), 61-75, 2016 | 62 | 2016 |
Stable incorporation of α‐smooth muscle actin into stress fibers is dependent on specific tropomyosin isoforms M Prunotto, M Bruschi, P Gunning, G Gabbiani, F Weibel, GM Ghiggeri, ... Cytoskeleton 72 (6), 257-267, 2015 | 46 | 2015 |
Phosphomimetic S3D cofilin binds but only weakly severs actin filaments WA Elam, W Cao, H Kang, A Huehn, GM Hocky, E Prochniewicz, ... Journal of Biological Chemistry 292 (48), 19565-19579, 2017 | 43 | 2017 |
A small molecule inhibitor of tropomyosin dissociates actin binding from tropomyosin-directed regulation of actin dynamics TT Bonello, M Janco, J Hook, A Byun, M Appaduray, I Dedova, ... Scientific reports 6 (1), 1-7, 2016 | 43 | 2016 |
Scribble and Discs-large direct initial assembly and positioning of adherens junctions during the establishment of apical-basal polarity TT Bonello, W Choi, M Peifer Development 146 (22), dev180976, 2019 | 39 | 2019 |
Adherens junction remodelling during mitotic rounding of pseudostratified epithelial cells M Aguilar‐Aragon, TT Bonello, GP Bell, GC Fletcher, BJ Thompson EMBO reports 21 (4), e49700, 2020 | 26 | 2020 |
Phase separation of Hippo signalling complexes TT Bonello, D Cai, GC Fletcher, K Wiengartner, V Pengilly, KS Lange, ... The EMBO Journal, e112863, 2023 | 15 | 2023 |
A picket fence function for adherens junctions in epithelial cell polarity T Bonello, M Aguilar-Aragon, A Tournier, BJ Thompson, JP Campanale Cells & Development, 203719, 2021 | 9 | 2021 |
Therapeutic targeting of the actin cytoskeleton in cancer T Bonello, J Coombes, G Schevzov, P Gunning, J Stehn Cytoskeleton and Human Disease, 181-200, 2012 | 8 | 2012 |