Julien Sage

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Tyler JacksAdresse e-mail validée de breakthroughcancer.org
Pawel K. MazurAssociate Professor, MD Anderson Cancer CenterAdresse e-mail validée de mdanderson.org
Nadine JahchanPostdoctoral Fellow at Stanford UniversityAdresse e-mail validée de stanford.edu
Jing Shan LimStanford University, Genome Institute of SingaporeAdresse e-mail validée de stanford.edu
Lauren Averett Byers, MD, MSMD Anderson Cancer CenterAdresse e-mail validée de mdanderson.org
Dian YangColumbia UniversityAdresse e-mail validée de stanford.edu
Monte WinslowStanford UniversityAdresse e-mail validée de stanford.edu
Or Gozani, M.D., Ph.D.Morris Herzstein Professor of Biology, Stanford UniversityAdresse e-mail validée de stanford.edu
Atul J. ButteDirector, Bakar Computational Health Sciences Institute, University of California, San FranciscoAdresse e-mail validée de ucsf.edu
John HeymachChair, Thoracic/Head and Neck Medical Oncology, MD Anderson Cancer CenterAdresse e-mail validée de mdanderson.org
Seth M RubinUniversity of California, Santa CruzAdresse e-mail validée de ucsc.edu
Charles RudinChief, Thoracic Oncology, Memorial Sloan Kettering Cancer CenterAdresse e-mail validée de mskcc.org
David MacPhersonFred Hutchinson Cancer Research CenterAdresse e-mail validée de fhcrc.org
Laura AttardiProfessor of Radiation Oncology and Genetics, Stanford UniversityAdresse e-mail validée de stanford.edu
Alexandros DrainasStanfordAdresse e-mail validée de stanford.edu
Triparna SenAssociate Professor, Icahn School of Medicine at Mount SinaiAdresse e-mail validée de mssm.edu
Caroline DiveProfessor of Pharmacology, University of ManchesterAdresse e-mail validée de cruk.manchester.ac.uk
Purvesh KhatriStanford UniversityAdresse e-mail validée de stanford.edu
Irving WeissmanDirector, Institute of Stem Cell Biology and Regenerative MedicineAdresse e-mail validée de stanford.edu
Don L. Gibbons, MD, PhDProfessor, Dept. of Thoracic/Head and Neck Medical Oncology, MD Anderson Cancer CenterAdresse e-mail validée de mdanderson.org

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Julien Sage

Professor of Pediatrics and Genetics, Stanford University

Adresse e-mail validée de stanford.edu - Page d'accueil

Cancer SCLC Stem Cells Cell Cycle Mouse models


Titre Trier par citations Trier par année Trier par titre	Citée par Citée par	Année
Comprehensive genomic profiles of small cell lung cancer J George, JS Lim, SJ Jang, Y Cun, L Ozretić, G Kong, F Leenders, X Lu, ... Nature 524 (7563), 47-53, 2015	2232	2015
Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer M Peifer, L Fernández-Cuesta, ML Sos, J George, D Seidel, LH Kasper, ... Nature genetics 44 (10), 1104-1110, 2012	1557	2012
Cellular mechanisms of tumour suppression by the retinoblastoma gene DL Burkhart, J Sage Nature Reviews Cancer 8 (9), 671-682, 2008	1307	2008
Small-cell lung cancer CM Rudin, E Brambilla, C Faivre-Finn, J Sage Nature Reviews Disease Primers 7 (1), 3, 2021	1177	2021
Molecular subtypes of small cell lung cancer: a synthesis of human and mouse model data CM Rudin, JT Poirier, LA Byers, C Dive, A Dowlati, J George, JV Heymach, ... Nature Reviews Cancer 19 (5), 289-297, 2019	1040	2019
Discovery and preclinical validation of drug indications using compendia of public gene expression data M Sirota, JT Dudley, J Kim, AP Chiang, AA Morgan, A Sweet-Cordero, ... Science translational medicine 3 (96), 96ra77-96ra77, 2011	902	2011
Targeted disruption of the three Rb-related genes leads to loss of G1 control and immortalization J Sage, GJ Mulligan, LD Attardi, A Miller, SQ Chen, B Williams, ... Genes & development 14 (23), 3037-3050, 2000	726	2000
Targeting DNA damage response promotes antitumor immunity through STING-mediated T-cell activation in small cell lung cancer T Sen, BL Rodriguez, L Chen, CMD Corte, N Morikawa, J Fujimoto, ... Cancer discovery 9 (5), 646-661, 2019	723	2019
Acute mutation of retinoblastoma gene function is sufficient for cell cycle re-entry J Sage, AL Miller, PA Pérez-Mancera, JM Wysocki, T Jacks Nature 424 (6945), 223-228, 2003	626	2003
Chemosensitive relapse in small cell lung cancer proceeds through an EZH2-SLFN11 axis EE Gardner, BH Lok, VE Schneeberger, P Desmeules, LA Miles, ... Cancer cell 31 (2), 286-299, 2017	482	2017
Intratumoural heterogeneity generated by Notch signalling promotes small-cell lung cancer JS Lim, A Ibaseta, MM Fischer, B Cancilla, G O’Young, S Cristea, VC Luca, ... Nature 545 (7654), 360-364, 2017	447	2017
From fly wings to targeted cancer therapies: a centennial for notch signaling P Ntziachristos, JS Lim, J Sage, I Aifantis Cancer cell 25 (3), 318-334, 2014	444	2014
CD47-blocking immunotherapies stimulate macrophage-mediated destruction of small-cell lung cancer K Weiskopf, NS Jahchan, PJ Schnorr, S Cristea, AM Ring, RL Maute, ... The Journal of clinical investigation 126 (7), 2610-2620, 2016	442	2016
SMYD3 links lysine methylation of MAP3K2 to Ras-driven cancer PK Mazur, N Reynoird, P Khatri, PWTC Jansen, AW Wilkinson, S Liu, ... Nature 510 (7504), 283-287, 2014	423	2014
Combined inhibition of BET family proteins and histone deacetylases as a potential epigenetics-based therapy for pancreatic ductal adenocarcinoma PK Mazur, A Herner, SS Mello, M Wirth, S Hausmann, FJ Sánchez-Rivera, ... Nature medicine 21 (10), 1163-1171, 2015	409	2015
A drug repositioning approach identifies tricyclic antidepressants as inhibitors of small cell lung cancer and other neuroendocrine tumors NS Jahchan, JT Dudley, PK Mazur, N Flores, D Yang, A Palmerton, ... Cancer discovery 3 (12), 1364-1377, 2013	400	2013
pRB family proteins are required for H3K27 trimethylation and Polycomb repression complexes binding to and silencing p16INK4a tumor suppressor gene Y Kotake, R Cao, P Viatour, J Sage, Y Zhang, Y Xiong Genes & development 21 (1), 49-54, 2007	376	2007
Nfib promotes metastasis through a widespread increase in chromatin accessibility SK Denny, D Yang, CH Chuang, JJ Brady, JS Lim, BM Grüner, SH Chiou, ... Cell 166 (2), 328-342, 2016	370	2016
PDGF signalling controls age-dependent proliferation in pancreatic β-cells H Chen, X Gu, Y Liu, J Wang, SE Wirt, R Bottino, H Schorle, J Sage, ... Nature 478 (7369), 349-355, 2011	316	2011
A crucial requirement for Hedgehog signaling in small cell lung cancer KS Park, LG Martelotto, M Peifer, ML Sos, AN Karnezis, MR Mahjoub, ... Nature medicine 17 (11), 1504-1508, 2011	294	2011

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