Stephen Neidle

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Gary ParkinsonUCL school of pharmacyAdresse e-mail validée de ucl.ac.uk
Shozeb HaiderUCL School of PharmacyAdresse e-mail validée de ucl.ac.uk
W. David WilsonRegents’ ProfessorAdresse e-mail validée de gsu.edu
Shankar BalasubramanianUniversity of CambridgeAdresse e-mail validée de cam.ac.uk
alan toddNIHR GSTFT/KCL Comprehensive Biomedical Research CentreAdresse e-mail validée de kcl.ac.uk
Helen M. BermanProfessor of Chemistry and Chemical BiologyAdresse e-mail validée de rcsb.rutgers.edu
Gavin CollieAstraZenecaAdresse e-mail validée de icr.ac.uk
Laurence HurleyProfessor of Medicinal Chemistry, CSO ReglageneAdresse e-mail validée de pharmacy.arizona.edu
ramon vilarImperial College LondonAdresse e-mail validée de imperial.ac.uk
Nancy H CampbellSenior Biocurator at HealxAdresse e-mail validée de healx.io
Sarah BurgeDepartment of Oncology, University of CambridgeAdresse e-mail validée de cam.ac.uk
Garry TaylorEmeritus Professor of Molecular Biophysics, University of St AndrewsAdresse e-mail validée de st-andrews.ac.uk
Julie E ReedImperial College LondonAdresse e-mail validée de imperial.ac.uk
Aaron G DaleGraduate Medical Student, Oxford University Adresse e-mail validée de medschool.ox.ac.uk
Aneel AggarwalProfessor, Icahn School of Medicine at Mount SinaiAdresse e-mail validée de mssm.edu
Dinshaw J. PatelMemorial Sloan-Kettering Cancer CenterAdresse e-mail validée de mskcc.org
Jean-Francois RiouMNHNAdresse e-mail validée de mnhn.fr
Bohdan SchneiderHead of Laboratory of Biomolecular Rcognition and Dir, Institute of Biotechnology, Czech AcademyAdresse e-mail validée de ibt.cas.cz

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Stephen Neidle

Emeritus Professor of Chemical Biology, The UCL School of Pharmacy, University of London

Adresse e-mail validée de ucl.ac.uk - Page d'accueil

drug design and discovery cancer nucleic acid structure quadruplex nucleic acids chemical biology


Titre Trier par citations Trier par année Trier par titre	Citée par Citée par	Année
Quadruplex DNA: sequence, topology and structure S Burge, GN Parkinson, P Hazel, AK Todd, S Neidle Nucleic acids research 34 (19), 5402-5415, 2006	2716	2006
Crystal structure of parallel quadruplexes from human telomeric DNA GN Parkinson, MPH Lee, S Neidle Nature 417 (6891), 876-880, 2002	2407	2002
Targeting G-quadruplexes in gene promoters: a novel anticancer strategy? S Balasubramanian, LH Hurley, S Neidle Nature reviews Drug discovery 10 (4), 261-275, 2011	1812	2011
Nucleic acids in chemistry and biology GM Blackburn Royal Society of Chemistry, 2006	1370	2006
Highly prevalent putative quadruplex sequence motifs in human DNA AK Todd, M Johnston, S Neidle Nucleic acids research 33 (9), 2901-2907, 2005	1161	2005
Inhibition of human telomerase by a G-quadruplex-interactive compound D Sun, B Thompson, BE Cathers, M Salazar, SM Kerwin, JO Trent, ... Journal of medicinal chemistry 40 (14), 2113-2116, 1997	1104	1997
Telomere maintenance as a target for anticancer drug discovery S Neidle, G Parkinson Nature Reviews Drug Discovery 1 (5), 383-393, 2002	808	2002
The G-quadruplex-interactive molecule BRACO-19 inhibits tumor growth, consistent with telomere targeting and interference with telomerase function AM Burger, F Dai, CM Schultes, AP Reszka, MJ Moore, JA Double, ... Cancer research 65 (4), 1489-1496, 2005	738	2005
A standard reference frame for the description of nucleic acid base-pair geometry WK Olson, M Bansal, SK Burley, RE Dickerson, M Gerstein, SC Harvey, ... Journal of molecular biology 313 (1), 229-237, 2001	716	2001
Putative DNA Quadruplex Formation within the Human c-kit Oncogene S Rankin, AP Reszka, J Huppert, M Zloh, GN Parkinson, AK Todd, ... Journal of the American Chemical Society 127 (30), 10584-10589, 2005	680	2005
Human telomeric G‐quadruplex: The current status of telomeric G‐quadruplexes as therapeutic targets in human cancer S Neidle The FEBS journal 277 (5), 1118-1125, 2010	667	2010
G-quadruplex nucleic acids as therapeutic targets S Balasubramanian, S Neidle Current opinion in chemical biology 13 (3), 345-353, 2009	655	2009
DNA minor-groove recognition by small molecules S Neidle Natural product reports 18 (3), 291-309, 2001	648	2001
Structure-based design of selective and potent G quadruplex-mediated telomerase inhibitors M Read, RJ Harrison, B Romagnoli, FA Tanious, SH Gowan, AP Reszka, ... Proceedings of the National Academy of Sciences 98 (9), 4844-4849, 2001	634	2001
Quadruplex nucleic acids as novel therapeutic targets S Neidle Journal of medicinal chemistry 59 (13), 5987-6011, 2016	594	2016
The structure of telomeric DNA S Neidle, GN Parkinson Current opinion in structural biology 13 (3), 275-283, 2003	579	2003
Quadruplex nucleic acids S Neidle, S Balasubramanian Royal Society of Chemistry, 2006	565	2006
Loop-length-dependent folding of G-quadruplexes P Hazel, J Huppert, S Balasubramanian, S Neidle Journal of the American Chemical Society 126 (50), 16405-16415, 2004	557	2004
The structures of quadruplex nucleic acids and their drug complexes S Neidle Current opinion in structural biology 19 (3), 239-250, 2009	527	2009
Structure of an Unprecedented G-Quadruplex Scaffold in the Human c-kit Promoter AT Phan, V Kuryavyi, S Burge, S Neidle, DJ Patel Journal of the American Chemical Society 129 (14), 4386-4392, 2007	511	2007

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