| Flavonoids: antioxidants or signalling molecules? RJ Williams, JPE Spencer, C Rice-Evans Free radical biology and medicine 36 (7), 838-849, 2004 | 2833 | 2004 |
| Flavonoids, cognition, and dementia: actions, mechanisms, and potential therapeutic utility for Alzheimer disease RJ Williams, JPE Spencer Free Radical Biology and Medicine 52 (1), 35-45, 2012 | 599 | 2012 |
| Association of plasma clusterin concentration with severity, pathology, and progression in Alzheimer disease M Thambisetty, A Simmons, L Velayudhan, A Hye, J Campbell, Y Zhang, ... Archives of general psychiatry 67 (7), 739-748, 2010 | 503 | 2010 |
| Flavonoids protect neurons from oxidized low-density-lipoprotein-induced apoptosis involving c-Jun N-terminal kinase (JNK), c-Jun and caspase-3 H Schroeter, JPE Spencer, C Rice-Evans, RJ Williams Biochemical Journal 358 (3), 547-557, 2001 | 493 | 2001 |
| MAPK signaling in neurodegeneration: influences of flavonoids and of nitric oxide H Schroeter, C Boyd, JPE Spencer, RJ Williams, E Cadenas, ... Neurobiology of aging 23 (5), 861-880, 2002 | 468 | 2002 |
| Modulation of pro-survival Akt/protein kinase B and ERK1/2 signaling cascades by quercetin and its in vivo metabolites underlie their action on neuronal viability JPE Spencer, C Rice-Evans, RJ Williams Journal of Biological Chemistry 278 (37), 34783-34793, 2003 | 445 | 2003 |
| Neuroinflammation: modulation by flavonoids and mechanisms of action JPE Spencer, K Vafeiadou, RJ Williams, D Vauzour Molecular aspects of medicine 33 (1), 83-97, 2012 | 398 | 2012 |
| Intracellular metabolism and bioactivity of quercetin and its in vivo metabolites JPE Spencer, GGC Kuhnle, RJ Williams, C Rice-Evans Biochemical Journal 372 (1), 173-181, 2003 | 330 | 2003 |
| Activation of pro‐survival Akt and ERK1/2 signalling pathways underlie the anti‐apoptotic effects of flavanones in cortical neurons D Vauzour, K Vafeiadou, C Rice‐Evans, RJ Williams, JPE Spencer Journal of neurochemistry 103 (4), 1355-1367, 2007 | 326 | 2007 |
| The citrus flavanone naringenin inhibits inflammatory signalling in glial cells and protects against neuroinflammatory injury K Vafeiadou, D Vauzour, HY Lee, A Rodriguez-Mateos, RJ Williams, ... Archives of Biochemistry and Biophysics 484 (1), 100-109, 2009 | 283 | 2009 |
| Phosphatidylinositol 3‐kinase is a central mediator of NMDA receptor signalling to MAP kinase (Erk1/2), Akt/PKB and CREB in striatal neurones MS Perkinton, J Ip, GL Wood, AJ Crossthwaite, RJ Williams Journal of neurochemistry 80 (2), 239-254, 2002 | 269 | 2002 |
| Phenolic antioxidants attenuate neuronal cell death following uptake of oxidized low-density lipoprotein H Schroeter, RJ Williams, R Matin, L Iversen, CA Rice-Evans Free Radical Biology and Medicine 29 (12), 1222-1233, 2000 | 257 | 2000 |
| Metals ions and neurodegeneration F Molina-Holgado, RC Hider, A Gaeta, R Williams, P Francis Biometals 20, 639-654, 2007 | 255 | 2007 |
| Nutrition for the ageing brain: towards evidence for an optimal diet D Vauzour, M Camprubi-Robles, S Miquel-Kergoat, C Andres-Lacueva, ... Ageing research reviews 35, 222-240, 2017 | 249 | 2017 |
| Hydrogen peroxide‐mediated phosphorylation of ERK1/2, Akt/PKB and JNK in cortical neurones: dependence on Ca2+ and PI3‐kinase AJ Crossthwaite, S Hasan, RJ Williams Journal of neurochemistry 80 (1), 24-35, 2002 | 249 | 2002 |
| Ca2+-permeable AMPA receptors induce phosphorylation of cAMP response element-binding protein through a phosphatidylinositol 3-kinase-dependent stimulation of the mitogen … MS Perkinton, TS Sihra, RJ Williams Journal of neuroscience 19 (14), 5861-5874, 1999 | 249 | 1999 |
| Synaptic NMDA receptor activation stimulates α-secretase amyloid precursor protein processing and inhibits amyloid-β production SE Hoey, RJ Williams, MS Perkinton Journal of Neuroscience 29 (14), 4442-4460, 2009 | 241 | 2009 |
| Contrasting influences of glucuronidation and O-methylation of epicatechin on hydrogen peroxide-induced cell death in neurons and fibroblasts JPE Spencer, H Schroeter, AJ Crossthwaithe, G Kuhnle, RJ Williams, ... Free Radical Biology and Medicine 31 (9), 1139-1146, 2001 | 214 | 2001 |
| (‐) Epicatechin stimulates ERK‐dependent cyclic AMP response element activity and up‐regulates GluR2 in cortical neurons H Schroeter, P Bahia, JPE Spencer, O Sheppard, M Rattray, E Cadenas, ... Journal of neurochemistry 101 (6), 1596-1606, 2007 | 204 | 2007 |
| Phosphatidylinositol 3-kinase is a key mediator of central sensitization in painful inflammatory conditions S Pezet, F Marchand, R D'Mello, J Grist, AK Clark, M Malcangio, ... Journal of Neuroscience 28 (16), 4261-4270, 2008 | 186 | 2008 |
Jeremy P E SpencerUniversity of ReadingAdresse e-mail validée de reading.ac.uk