| Targeting metabolic transformation for cancer therapy DA Tennant, RV Durán, E Gottlieb Nature reviews cancer 10 (4), 267-277, 2010 | 1309 | 2010 |
| Hypoxia and metabolic adaptation of cancer cells KL Eales, KER Hollinshead, DA Tennant Oncogenesis 5 (1), e190-e190, 2016 | 838 | 2016 |
| A roadmap for interpreting 13C metabolite labeling patterns from cells JM Buescher, MR Antoniewicz, LG Boros, SC Burgess, H Brunengraber, ... Current opinion in biotechnology 34, 189-201, 2015 | 666 | 2015 |
| Cell-Permeating α-Ketoglutarate Derivatives Alleviate Pseudohypoxia in Succinate Dehydrogenase-Deficient Cells ED MacKenzie, MA Selak, DA Tennant, LJ Payne, S Crosby, ... Molecular and cellular biology 27 (9), 3282-3289, 2007 | 436 | 2007 |
| Glucose utilization via glycogen phosphorylase sustains proliferation and prevents premature senescence in cancer cells E Favaro, K Bensaad, MG Chong, DA Tennant, DJP Ferguson, C Snell, ... Cell metabolism 16 (6), 751-764, 2012 | 433 | 2012 |
| New aspects of amino acid metabolism in cancer L Vettore, RL Westbrook, DA Tennant British journal of cancer 122 (2), 150-156, 2020 | 400 | 2020 |
| Nicotinamide riboside augments the aged human skeletal muscle NAD+ metabolome and induces transcriptomic and anti-inflammatory signatures YS Elhassan, K Kluckova, RS Fletcher, MS Schmidt, A Garten, CL Doig, ... Cell reports 28 (7), 1717-1728. e6, 2019 | 380 | 2019 |
| Fumarate Is Cardioprotective via Activation of the Nrf2 Antioxidant Pathway H Ashrafian, G Czibik, M Bellahcene, D Aksentijević, AC Smith, ... Cell Metabolism 15 (3), 361-371, 2012 | 317 | 2012 |
| Metabolic transformation in cancer DA Tennant, RV Durán, H Boulahbel, E Gottlieb Carcinogenesis 30 (8), 1269-1280, 2009 | 304 | 2009 |
| Loss of succinate dehydrogenase activity results in dependency on pyruvate carboxylation for cellular anabolism C Lussey-Lepoutre, KER Hollinshead, C Ludwig, M Menara, A Morin, ... Nature communications 6 (1), 8784, 2015 | 239 | 2015 |
| Hypoxia inducible factors in liver disease and hepatocellular carcinoma: current understanding and future directions GK Wilson, DA Tennant, JA McKeating Journal of hepatology 61 (6), 1397-1406, 2014 | 224 | 2014 |
| Metabolic profiling of hypoxic cells revealed a catabolic signature required for cell survival C Frezza, L Zheng, DA Tennant, DB Papkovsky, BA Hedley, G Kalna, ... PloS one 6 (9), e24411, 2011 | 217 | 2011 |
| Reactivating HIF prolyl hydroxylases under hypoxia results in metabolic catastrophe and cell death DA Tennant, C Frezza, ED MacKenzie, QD Nguyen, L Zheng, MA Selak, ... Oncogene 28 (45), 4009-4021, 2009 | 148 | 2009 |
| A role for cytosolic fumarate hydratase in urea cycle metabolism and renal neoplasia J Adam, M Yang, C Bauerschmidt, M Kitagawa, L O’Flaherty, ... Cell reports 3 (5), 1440-1448, 2013 | 102 | 2013 |
| Development and validation of a combined hypoxia and immune prognostic classifier for head and neck cancer JM Brooks, AN Menezes, M Ibrahim, L Archer, N Lal, CJ Bagnall, ... Clinical Cancer Research 25 (17), 5315-5328, 2019 | 97 | 2019 |
| Metabolic plasticity in CLL: adaptation to the hypoxic niche KM Koczula, C Ludwig, R Hayden, L Cronin, G Pratt, H Parry, D Tennant, ... Leukemia 30 (1), 65-73, 2016 | 95 | 2016 |
| Isocitrate dehydrogenase (IDH), succinate dehydrogenase (SDH), fumarate hydratase (FH): three players for one phenotype in cancer? G Laurenti, DA Tennant Biochemical Society Transactions 44 (4), 1111-1116, 2016 | 94 | 2016 |
| Oncogenic IDH1 mutations promote enhanced proline synthesis through PYCR1 to support the maintenance of mitochondrial redox homeostasis KER Hollinshead, H Munford, KL Eales, C Bardella, C Li, ... Cell reports 22 (12), 3107-3114, 2018 | 92 | 2018 |
| HIF prolyl hydroxylase-3 mediates alpha-ketoglutarate-induced apoptosis and tumor suppression DA Tennant, E Gottlieb Journal of molecular medicine 88 (8), 839-849, 2010 | 87 | 2010 |
| IDH1 mutations in gliomas: when an enzyme loses its grip C Frezza, DA Tennant, E Gottlieb Cancer cell 17 (1), 7-9, 2010 | 87 | 2010 |
