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John M Leech
John M Leech
Adresse e-mail validée de pfizer.com
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Staphylococcus aureus Colonization: Modulation of Host Immune Response and Impact on Human Vaccine Design
AF Brown, JM Leech, TR Rogers, RM McLoughlin
Frontiers in immunology 4, 507, 2014
3342014
Alteration of the cutaneous microbiome in psoriasis and potential role in Th17 polarization
HW Chang, D Yan, R Singh, J Liu, X Lu, D Ucmak, K Lee, L Afifi, ...
Microbiome 6, 1-27, 2018
2922018
Memory Th1 Cells Are Protective in Invasive Staphylococcus aureus Infection
AF Brown, AG Murphy, SJ Lalor, JM Leech, KM O’Keeffe, M Mac Aogáin, ...
PLoS pathogens 11 (11), e1005226, 2015
1732015
Manipulation of autophagy in phagocytes facilitates Staphylococcus aureus bloodstream infection
KM O'Keeffe, MM Wilk, JM Leech, AG Murphy, M Laabei, IR Monk, ...
Infection and immunity 83 (9), 3445-3457, 2015
1052015
IL-10 plays opposing roles during Staphylococcus aureus systemic and localized infections
JM Leech, KA Lacey, ME Mulcahy, E Medina, RM McLoughlin
The Journal of Immunology 198 (6), 2352-2365, 2017
1022017
Promoting transplantation tolerance; adoptive regulatory T cell therapy
N Safinia, J Leech, M Hernandez-Fuentes, R Lechler, G Lombardi
Clinical & Experimental Immunology 172 (2), 158-168, 2013
862013
Toxin-triggered interleukin-1 receptor signaling enables early-life discrimination of pathogenic versus commensal skin bacteria
JM Leech, MO Dhariwala, MM Lowe, K Chu, GR Merana, C Cornuot, ...
Cell host & microbe 26 (6), 795-809. e5, 2019
792019
Interleukin-22 regulates antimicrobial peptide expression and keratinocyte differentiation to control Staphylococcus aureus colonization of the nasal mucosa
ME Mulcahy, JM Leech, JC Renauld, KHG Mills, RM McLoughlin
Mucosal immunology 9 (6), 1429-1441, 2016
722016
Evidence of potent humoral immune activity in COVID-19-infected kidney transplant recipients
S Hartzell, S Bin, C Benedetti, M Haverly, L Gallon, G Zaza, LV Riella, ...
American Journal of Transplantation 20 (11), 3149-3161, 2020
702020
Regulatory T cells promote innate inflammation after skin barrier breach via TGF-β activation
JM Moreau, MO Dhariwala, V Gouirand, DP Boda, IC Boothby, MM Lowe, ...
Science immunology 6 (62), eabg2329, 2021
382021
A streamlined whole blood CyTOF workflow defines a circulating immune cell signature of COVID‐19
D Geanon, B Lee, E Gonzalez‐Kozlova, G Kelly, D Handler, B Upadhyaya, ...
Cytometry Part A 99 (5), 446-461, 2021
362021
Long-term tolerance to skin commensals is established neonatally through a specialized dendritic cell subgroup
A Weckel, MO Dhariwala, K Ly, VM Tran, OT Ojewumi, JB Riggs, ...
Immunity 56 (6), 1239-1254. e7, 2023
322023
Sampling the host response to SARS-CoV-2 in hospitals under siege
AW Charney, NW Simons, K Mouskas, L Lepow, E Cheng, J Le Berichel, ...
Nature Medicine 26 (8), 1157-1158, 2020
312020
The Staphylococcus aureus cell wall-anchored protein clumping factor A is an important T cell antigen
KA Lacey, JM Leech, SJ Lalor, N McCormack, JA Geoghegan, ...
Infection and immunity 85 (12), 10.1128/iai. 00549-17, 2017
292017
Whole-body imaging of adoptively transferred T cells using magnetic resonance imaging, single photon emission computed tomography and positron emission tomography techniques …
JM Leech, E Sharif-Paghaleh, J Maher, L Livieratos, RI Lechler, ...
Clinical & Experimental Immunology 172 (2), 169-177, 2013
182013
Unexplored microbial diversity from 2,500 food metagenomes and links with the human microbiome
N Carlino, A Blanco-Míguez, M Punčochář, C Mengoni, F Pinto, A Tatti, ...
Cell 187 (20), 5775-5795. e15, 2024
172024
Staphylococcus aureus-induced immunosuppression mediated by IL-10 and IL-27 facilitates nasal colonisation
AM Kelly, JM Leech, SL Doyle, RM McLoughlin
PLoS Pathogens 18 (7), e1010647, 2022
172022
A streamlined CyTOF workflow to facilitate standardized multi-site immune profiling of COVID-19 patients
D Geanon, B Lee, G Kelly, D Handler, B Upadhyaya, J Leech, M Herbinet, ...
medRxiv, 2020.06. 26.20141341, 2020
112020
Monitoring the efficacy of dendritic cell vaccination by early detection of 99mTc‐HMPAO‐labelled CD4+ T cells
E Sharif‐Paghaleh, J Leech, K Sunassee, N Ali, P Sagoo, RI Lechler, ...
European Journal of Immunology 44 (7), 2188-2191, 2014
112014
Seasonal variation in the Canastra cheese mycobiota
JGP Martin, JMM Silva, ICR César, M Da Silva, SA Santana, TGR Veloso, ...
Frontiers in microbiology 13, 1076672, 2023
102023
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