Chronic critical illness and the persistent inflammation, immunosuppression, and catabolism syndrome RB Hawkins, SL Raymond, JA Stortz, H Horiguchi, SC Brakenridge, ... Frontiers in immunology 9, 1511, 2018 | 261 | 2018 |
Murine models of sepsis and trauma: can we bridge the gap? JA Stortz, SL Raymond, JC Mira, LL Moldawer, AM Mohr, PA Efron ILAR journal 58 (1), 90-105, 2017 | 173 | 2017 |
Innate immunity in the persistent inflammation, immunosuppression, and catabolism syndrome and its implications for therapy H Horiguchi, TJ Loftus, RB Hawkins, SL Raymond, JA Stortz, MKK Hollen, ... Frontiers in immunology 9, 595, 2018 | 166 | 2018 |
Microbial recognition and danger signals in sepsis and trauma SL Raymond, DC Holden, JC Mira, JA Stortz, TJ Loftus, AM Mohr, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1863 (10 …, 2017 | 164 | 2017 |
Evidence for persistent immune suppression in patients who develop chronic critical illness after sepsis JA Stortz, TJ Murphy, SL Raymond, JC Mira, R Ungaro, ML Dirain, ... Shock 49 (3), 249-258, 2018 | 133 | 2018 |
Benchmarking clinical outcomes and the immunocatabolic phenotype of chronic critical illness after sepsis in surgical intensive care unit patients JA Stortz, JC Mira, SL Raymond, TJ Loftus, T Ozrazgat-Baslanti, Z Wang, ... Journal of Trauma and Acute Care Surgery 84 (2), 342-349, 2018 | 121 | 2018 |
The epidemiology of chronic critical illness after severe traumatic injury at two level–one trauma centers JC Mira, J Cuschieri, T Ozrazgat-Baslanti, Z Wang, GL Ghita, TJ Loftus, ... Critical care medicine 45 (12), 1989-1996, 2017 | 113 | 2017 |
Immunological defects in neonatal sepsis and potential therapeutic approaches SL Raymond, JA Stortz, JC Mira, SD Larson, JL Wynn, LL Moldawer Frontiers in pediatrics 5, 14, 2017 | 89 | 2017 |
Current epidemiology of surgical sepsis: discordance between inpatient mortality and 1-year outcomes SC Brakenridge, PA Efron, MC Cox, JA Stortz, RB Hawkins, G Ghita, ... Annals of surgery 270 (3), 502-510, 2019 | 81 | 2019 |
Myeloid-derived suppressor cell function and epigenetic expression evolves over time after surgical sepsis MKK Hollen, JA Stortz, D Darden, ML Dirain, DC Nacionales, RB Hawkins, ... Critical Care 23, 1-16, 2019 | 80 | 2019 |
Sepsis and Critical Illness Research Center investigators: protocols and standard operating procedures for a prospective cohort study of sepsis in critically ill surgical patients TJ Loftus, JC Mira, T Ozrazgat-Baslanti, GL Ghita, Z Wang, JA Stortz, ... BMJ open 7 (7), e015136, 2017 | 73 | 2017 |
The impact of age on the innate immune response and outcomes after severe sepsis/septic shock in trauma and surgical intensive care unit patients SC Brakenridge, PA Efron, JA Stortz, T Ozrazgat-Baslanti, G Ghita, ... Journal of Trauma and Acute Care Surgery 85 (2), 247-255, 2018 | 57 | 2018 |
Phenotypic heterogeneity by site of infection in surgical sepsis: a prospective longitudinal study JA Stortz, MC Cox, RB Hawkins, GL Ghita, BA Brumback, AM Mohr, ... Critical Care 24, 1-14, 2020 | 42 | 2020 |
Cell-free nuclear, but not mitochondrial, DNA concentrations correlate with the early host inflammatory response after severe trauma JA Stortz, RB Hawkins, DC Holden, SL Raymond, Z Wang, ... Scientific reports 9 (1), 13648, 2019 | 41 | 2019 |
Persistent inflammation and anemia among critically ill septic patients TJ Loftus, JC Mira, JA Stortz, T Ozrazgat-Baslanti, GL Ghita, Z Wang, ... Journal of Trauma and Acute Care Surgery 86 (2), 260-267, 2019 | 41 | 2019 |
Old mice demonstrate organ dysfunction as well as prolonged inflammation, immunosuppression, and weight loss in a modified surgical sepsis model JA Stortz, MKK Hollen, DC Nacionales, H Horiguchi, R Ungaro, ML Dirain, ... Critical care medicine 47 (11), e919-e929, 2019 | 40 | 2019 |
Abdominal sepsis patients have a high incidence of chronic critical illness with dismal long-term outcomes MC Cox, SC Brakenridge, JA Stortz, RB Hawkins, DB Darden, GL Ghita, ... The American Journal of Surgery 220 (6), 1467-1474, 2020 | 39 | 2020 |
The postinjury inflammatory state and the bone marrow response to anemia TJ Loftus, JC Mira, ES Miller, KB Kannan, JM Plazas, D Delitto, JA Stortz, ... American journal of respiratory and critical care medicine 198 (5), 629-638, 2018 | 39 | 2018 |
Age and sex influence the hippocampal response and recovery following sepsis J Barter, A Kumar, JA Stortz, MK Hollen, D Nacionales, PA Efron, ... Molecular neurobiology 56, 8557-8572, 2019 | 37 | 2019 |
Prospective validation of a transcriptomic metric in severe trauma SL Raymond, RB Hawkins, Z Wang, JC Mira, JA Stortz, F Han, JD Lanz, ... Annals of surgery 271 (5), 802-810, 2020 | 31 | 2020 |