| Small molecule modulators of K eap1‐N rf2‐ARE pathway as potential preventive and therapeutic agents S Magesh, Y Chen, L Hu Medicinal research reviews 32 (4), 687-726, 2012 | 905 | 2012 |
| Efficient Baylis− Hillman reaction using stoichiometric base catalyst and an aqueous medium C Yu, B Liu, L Hu The Journal of Organic Chemistry 66 (16), 5413-5418, 2001 | 340 | 2001 |
| Discovery of direct inhibitors of Keap1–Nrf2 protein–protein interaction as potential therapeutic and preventive agents DA Abed, M Goldstein, H Albanyan, H Jin, L Hu Acta Pharmaceutica Sinica B 5 (4), 285-299, 2015 | 322 | 2015 |
| Drug delivery: principles and applications B Wang, L Hu, TJ Siahaan John Wiley & Sons, 2016 | 295 | 2016 |
| Design of anticancer prodrugs for reductive activation Y Chen, L Hu Medicinal Research Reviews 29 (1), 29-64, 2009 | 280 | 2009 |
| Discovery of a small-molecule inhibitor and cellular probe of Keap1–Nrf2 protein–protein interaction L Hu, S Magesh, L Chen, L Wang, TA Lewis, Y Chen, C Khodier, ... Bioorganic & medicinal chemistry letters 23 (10), 3039-3043, 2013 | 216 | 2013 |
| Enzyme-mediated hydrolytic activation of prodrugs Y Yang, H Aloysius, D Inoyama, Y Chen, L Hu Acta Pharmaceutica Sinica B 1 (3), 143-159, 2011 | 192 | 2011 |
| Immunomodulators targeting the PD‐1/PD‐L1 protein‐protein interaction: from antibodies to small molecules J Yang, L Hu Medicinal research reviews 39 (1), 265-301, 2019 | 184 | 2019 |
| Insects: an underrepresented resource for the discovery of biologically active natural products L Seabrooks, L Hu Acta Pharmaceutica Sinica B 7 (4), 409-426, 2017 | 159 | 2017 |
| Nitroreductase: a prodrug-activating enzyme for cancer gene therapy. PF Searle, MJ Chen, L Hu, PR Race, AL Lovering, JI Grove, C Guise, ... Clinical & Experimental Pharmacology & Physiology 31 (11), 2004 | 153 | 2004 |
| Samarium (0) and 1, 1 ‘-dioctyl-4, 4 ‘-bipyridinium dibromide: a novel electron-transfer system for the chemoselective reduction of aromatic nitro groups C Yu, B Liu, L Hu The Journal of Organic Chemistry 66 (3), 919-924, 2001 | 136 | 2001 |
| Successful Baylis− Hillman reaction of acrylamide with aromatic aldehydes C Yu, L Hu The Journal of Organic Chemistry 67 (1), 219-223, 2002 | 132 | 2002 |
| Analysis of multiple metabolites of tocopherols and tocotrienols in mice and humans Y Zhao, MJ Lee, C Cheung, JH Ju, YK Chen, B Liu, LQ Hu, CS Yang Journal of agricultural and food chemistry 58 (8), 4844-4852, 2010 | 121 | 2010 |
| Optimization of fluorescently labeled Nrf2 peptide probes and the development of a fluorescence polarization assay for the discovery of inhibitors of Keap1-Nrf2 interaction D Inoyama, Y Chen, X Huang, LJ Beamer, ANT Kong, L Hu Journal of biomolecular screening 17 (4), 435-447, 2012 | 112 | 2012 |
| Anti-NF-κB and anti-inflammatory activities of synthetic isothiocyanates: effect of chemical structures and cellular signaling A Prawan, CLL Saw, TO Khor, YS Keum, S Yu, L Hu, AN Kong Chemico-biological interactions 179 (2-3), 202-211, 2009 | 103 | 2009 |
| Nrf2 activation through the inhibition of Keap1–Nrf2 protein–protein interaction S Lee, L Hu Medicinal Chemistry Research 29, 846-867, 2020 | 97 | 2020 |
| Design, Synthesis, Evaluation, and Structural Studies of C2-Symmetric Small Molecule Inhibitors of Programmed Cell Death-1/Programmed Death-Ligand 1 … S Basu, J Yang, B Xu, K Magiera-Mularz, L Skalniak, B Musielak, ... Journal of medicinal chemistry 62 (15), 7250-7263, 2019 | 96 | 2019 |
| Nitroaryl phosphoramides as novel prodrugs for E. coli nitroreductase activation in enzyme prodrug therapy L Hu, C Yu, Y Jiang, J Han, Z Li, P Browne, PR Race, RJ Knox, PF Searle, ... Journal of medicinal chemistry 46 (23), 4818-4821, 2003 | 95 | 2003 |
| Kinetic analyses of Keap1–Nrf2 interaction and determination of the minimal Nrf2 peptide sequence required for Keap1 binding using surface plasmon resonance Y Chen, D Inoyama, ANT Kong, LJ Beamer, L Hu Chemical biology & drug design 78 (6), 1014-1021, 2011 | 90 | 2011 |
| Nitrobenzocyclophosphamides as potential prodrugs for bioreductive activation: synthesis, stability, enzymatic reduction, and antiproliferative activity in cell culture Z Li, J Han, Y Jiang, P Browne, RJ Knox, L Hu Bioorganic & medicinal chemistry 11 (19), 4171-4178, 2003 | 87 | 2003 |
Ah-Ng Tony KongRutgers universityAdresse e-mail validée de pharmacy.rutgers.edu