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Clonal neoantigens elicit T cell immunoreactivity and sensitivity to immune checkpoint blockade

N McGranahan, AJS Furness, R Rosenthal, S Ramskov, R Lyngaa, ...

Science 351 (6280), 1463-1469, 2016

Exigences : US National Institutes of Health, Cancer Research UK, National Institute for …

[HTML] nejm.org

Tracking the evolution of non–small-cell lung cancer

M Jamal-Hanjani, GA Wilson, N McGranahan, NJ Birkbak, TBK Watkins, ...

New England Journal of Medicine 376 (22), 2109-2121, 2017

Exigences : Cancer Research UK, UK Medical Research Council, National Institute for …

Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution

C Abbosh, NJ Birkbak, GA Wilson, M Jamal-Hanjani, T Constantin, ...

Nature 545 (7655), 446-451, 2017

Exigences : US National Institutes of Health, Versus Arthritis, UK, Cancer Research UK …

Chromosomal instability drives metastasis through a cytosolic DNA response

SF Bakhoum, B Ngo, AM Laughney, JA Cavallo, CJ Murphy, P Ly, P Shah, ...

Nature 553 (7689), 467-472, 2018

Exigences : US National Science Foundation, US Department of Defense, US National …

Allele-specific HLA loss and immune escape in lung cancer evolution

N McGranahan, R Rosenthal, CT Hiley, AJ Rowan, TBK Watkins, ...

Cell 171 (6), 1259-1271. e11, 2017

Exigences : Versus Arthritis, UK, Cancer Research UK, UK Medical Research Council …

[PDF] cell.com

Tracking cancer evolution reveals constrained routes to metastases: TRACERx renal

S Turajlic, H Xu, K Litchfield, A Rowan, T Chambers, JI Lopez, D Nicol, ...

Cell 173 (3), 581-594. e12, 2018

Exigences : US National Institutes of Health, Cancer Research UK, UK Medical Research …

Meta-analysis of tumor-and T cell-intrinsic mechanisms of sensitization to checkpoint inhibition

K Litchfield, JL Reading, C Puttick, K Thakkar, C Abbosh, R Bentham, ...

Cell 184 (3), 596-614. e14, 2021

Exigences : US National Institutes of Health, Cancer Research UK, UK Medical Research …

Deterministic evolutionary trajectories influence primary tumor growth: TRACERx renal

S Turajlic, H Xu, K Litchfield, A Rowan, S Horswell, T Chambers, ...

Cell 173 (3), 595-610. e11, 2018

Exigences : Cancer Research UK, UK Medical Research Council, National Institute for …

Fc effector function contributes to the activity of human anti-CTLA-4 antibodies

FA Vargas, AJS Furness, K Litchfield, K Joshi, R Rosenthal, E Ghorani, ...

Cancer cell 33 (4), 649-663. e4, 2018

Exigences : Blood Cancer UK, Cancer Research UK, UK Medical Research Council, National …

Relapsed neuroblastomas show frequent RAS-MAPK pathway mutations

TF Eleveld, DA Oldridge, V Bernard, J Koster, LC Daage, SJ Diskin, ...

Nature genetics 47 (8), 864-871, 2015

Exigences : US National Institutes of Health

[PDF] nih.gov

Evolution and clinical impact of co-occurring genetic alterations in advanced-stage EGFR-mutant lung cancers

CM Blakely, TBK Watkins, W Wu, B Gini, JJ Chabon, CE McCoach, ...

Nature genetics 49 (12), 1693-1704, 2017

Exigences : US National Institutes of Health, Cancer Research UK, UK Medical Research …

Fc-optimized anti-CD25 depletes tumor-infiltrating regulatory T cells and synergizes with PD-1 blockade to eradicate established tumors

FA Vargas, AJS Furness, I Solomon, K Joshi, L Mekkaoui, MH Lesko, ...

Immunity 46 (4), 577-586, 2017

Exigences : Blood Cancer UK, Cancer Research UK, UK Engineering and Physical Sciences …

Characterizing genetic intra-tumor heterogeneity across 2,658 human cancer genomes

SC Dentro, I Leshchiner, K Haase, M Tarabichi, J Wintersinger, ...

Cell 184 (8), 2239-2254. e39, 2021

Exigences : US National Institutes of Health, Research Foundation (Flanders), Instituts …

Pervasive chromosomal instability and karyotype order in tumour evolution

TBK Watkins, EL Lim, M Petkovic, S Elizalde, NJ Birkbak, GA Wilson, ...

Nature 587 (7832), 126-132, 2020

Exigences : US Department of Defense, US National Institutes of Health, Helmholtz …

[PDF] aacrjournals.org

Tracking the genomic evolution of esophageal adenocarcinoma through neoadjuvant chemotherapy

N Murugaesu, GA Wilson, NJ Birkbak, TBK Watkins, N McGranahan, ...

Cancer discovery 5 (8), 821-831, 2015

Exigences : Cancer Research UK, National Institute for Health Research, UK, European …

Interplay between whole-genome doubling and the accumulation of deleterious alterations in cancer evolution

S López, EL Lim, S Horswell, K Haase, A Huebner, M Dietzen, ...

Nature genetics 52 (3), 283-293, 2020

Exigences : Versus Arthritis, UK, Cancer Research UK, UK Medical Research Council …

[PDF] nih.gov

Tracking early lung cancer metastatic dissemination in TRACERx using ctDNA

C Abbosh, AM Frankell, T Harrison, J Kisistok, A Garnett, L Johnson, ...

Nature 616 (7957), 553-562, 2023

Exigences : US National Institutes of Health, Howard Hughes Medical Institute, Versus …

[HTML] nature.com

The evolution of lung cancer and impact of subclonal selection in TRACERx

AM Frankell, M Dietzen, M Al Bakir, EL Lim, T Karasaki, S Ward, ...

Nature 616 (7957), 525-533, 2023

Exigences : Versus Arthritis, UK, Cancer Research UK, UK Engineering and Physical …

[HTML] nature.com

Antibodies against endogenous retroviruses promote lung cancer immunotherapy

KW Ng, J Boumelha, KSS Enfield, J Almagro, H Cha, O Pich, T Karasaki, ...

Nature 616 (7957), 563-573, 2023

Exigences : US National Institutes of Health, Versus Arthritis, UK, Cancer Research UK …