MicroRNA inhibition of translation initiation in vitro by targeting the cap-binding complex eIF4F G Mathonnet, MR Fabian, YV Svitkin, A Parsyan, L Huck, T Murata, S Biffo, ... Science 317 (5845), 1764-1767, 2007 | 817 | 2007 |
A nuclear cap binding protein complex involved in pre-mRNA splicing E Izaurralde, J Lewis, C McGuigan, M Jankowska, E Darzynkiewicz, ... Cell 78 (4), 657-668, 1994 | 702 | 1994 |
Synthesis and properties of mRNAs containing the novel “anti-reverse” cap analogs 7-methyl (3′-O-methyl) GpppG and 7-methyl (3′-deoxy) GpppG J STEPINSKI, C WADDELL, R STOLARSKI, E DARZYNKIEWICZ, ... Rna 7 (10), 1486-1495, 2001 | 561 | 2001 |
Novel “anti-reverse” cap analogs with superior translational properties J Jemielity, T Fowler, J Zuberek, J Stepinski, M Lewdorowicz, ... Rna 9 (9), 1108-1122, 2003 | 458 | 2003 |
Biophysical studies of eIF4E cap-binding protein: recognition of mRNA 5′ cap structure and synthetic fragments of eIF4G and 4E-BP1 proteins A Niedzwiecka, J Marcotrigiano, J Stepinski, M Jankowska-Anyszka, ... Journal of molecular biology 319 (3), 615-635, 2002 | 458 | 2002 |
The trimethylguanosine cap structure of U1 snRNA is a component of a bipartite nuclear targeting signal J Hamm, E Darzynkiewicz, SM Tahara, IW Mattaj Cell 62 (3), 569-577, 1990 | 367 | 1990 |
Phosphorothioate cap analogs stabilize mRNA and increase translational efficiency in mammalian cells E Grudzien-Nogalska, J Jemielity, J Kowalska, E Darzynkiewicz, ... Rna 13 (10), 1745-1755, 2007 | 289 | 2007 |
Phosphorothioate cap analogs increase stability and translational efficiency of RNA vaccines in immature dendritic cells and induce superior immune responses in vivo AN Kuhn, M Diken, S Kreiter, A Selmi, J Kowalska, J Jemielity, ... Gene therapy 17 (8), 961-971, 2010 | 279 | 2010 |
Phosphorylation of Eukaryotic Protein Synthesis Initiation Factor 4E at Ser-209∗ B Joshi, AL Cai, BD Keiper, WB Minich, R Mendez, CM Beach, J Stepinski, ... Journal of Biological Chemistry 270 (24), 14597-14603, 1995 | 277 | 1995 |
Novel cap analogs for in vitro synthesis of mRNAs with high translational efficiency EWA Grudzien, J Stepinski, M Jankowska-Anyszka, R Stolarski, ... Rna 10 (9), 1479-1487, 2004 | 270 | 2004 |
A cap binding protein that may mediate nuclear export of RNA polymerase II-transcribed RNAs. E Izaurralde, J Stepinski, E Darzynkiewicz, IW Mattaj The Journal of cell biology 118 (6), 1287-1295, 1992 | 207 | 1992 |
Diversity in the signals required for nuclear accumulation of U snRNPs and variety in the pathways of nuclear transport. U Fischer, E Darzynkiewicz, SM Tahara, NA Dathan, R Lührmann, ... The Journal of cell biology 113 (4), 705-714, 1991 | 190 | 1991 |
Characterization of hMTr1, a human Cap1 2′-O-ribose methyltransferase F Bélanger, J Stepinski, E Darzynkiewicz, J Pelletier Journal of Biological Chemistry 285 (43), 33037-33044, 2010 | 183 | 2010 |
Synthesis and use of anti-reverse mRNA cap analogues E Darzynkiewicz, RE Rhoads, J Stepinski US Patent 7,074,596, 2006 | 171 | 2006 |
Phosphorylation of eIF4E attenuates its interaction with mRNA 5′ cap analogs by electrostatic repulsion: intein-mediated protein ligation strategy to obtain phosphorylated protein J Zuberek, A Wyslouch-Cieszynska, A Niedzwiecka, M Dadlez, ... Rna 9 (1), 52-61, 2003 | 170 | 2003 |
Synthesis and characterization of mRNA cap analogs containing phosphorothioate substitutions that bind tightly to eIF4E and are resistant to the decapping pyrophosphatase DcpS J Kowalska, M Lewdorowicz, J Zuberek, E Grudzien-Nogalska, ... Rna 14 (6), 1119-1131, 2008 | 161 | 2008 |
Quantitative assessment of mRNA cap analogues as inhibitors of in vitro translation A Cai, M Jankowska-Anyszka, A Centers, L Chlebicka, J Stepinski, ... Biochemistry 38 (26), 8538-8547, 1999 | 150 | 1999 |
mRNA decapping is promoted by an RNA-binding channel in Dcp2 MV Deshmukh, BN Jones, DU Quang-Dang, J Flinders, SN Floor, C Kim, ... Molecular cell 29 (3), 324-336, 2008 | 130 | 2008 |
Most mRNAs in the nematode Ascaris lumbricoides are trans-spliced: a role for spliced leader addition in translational efficiency. PA Maroney, JA Denker, E Darzynkiewicz, R Laneve, TW Nilsen Rna 1 (7), 714-723, 1995 | 130 | 1995 |
Differential inhibition of mRNA degradation pathways by novel cap analogs E Grudzien, M Kalek, J Jemielity, E Darzynkiewicz, RE Rhoads Journal of Biological Chemistry 281 (4), 1857-1867, 2006 | 120 | 2006 |