Antibiotic discovery: where have we come from, where do we go? B Ribeiro da Cunha, LP Fonseca, CRC Calado Antibiotics 8 (2), 45, 2019 | 425 | 2019 |
Development and characterization of a new plasmid delivery system based on chitosan–sodium deoxycholate nanoparticles A Cadete, L Figueiredo, R Lopes, CCR Calado, AJ Almeida, ... European journal of pharmaceutical sciences 45 (4), 451-458, 2012 | 76 | 2012 |
Effect of pre-fermentation on the production of cutinase by a recombinant Saccharomyces cerevisiae CRC Calado, SMS Monteiro, JMS Cabral, LP Fonseca Journal of bioscience and bioengineering 93 (4), 354-359, 2002 | 57 | 2002 |
Optimisation of culture conditions and characterisation of cutinase produced by recombinant Saccharomyces cerevisiae CRC Calado, MÂ Taipa, JMS Cabral, LP Fonseca Enzyme and Microbial Technology 31 (1-2), 161-170, 2002 | 55 | 2002 |
Development of a fed-batch cultivation strategy for the enhanced production and secretion of cutinase by a recombinant Saccharomyces cerevisiae SU50 strain CRC Calado, C Almeida, JMS Cabral, LP Fonseca Journal of bioscience and bioengineering 96 (2), 141-148, 2003 | 52 | 2003 |
Integration of production and aqueous two-phase systems extraction of extracellular Fusarium solani pisi cutinase fusion proteins MT Cunha, MJL Costa, CRC Calado, LP Fonseca, MR Aires-Barros, ... Journal of biotechnology 100 (1), 55-64, 2003 | 45 | 2003 |
Integration of the production and the purification processes of cutinase secreted by a recombinant Saccharomyces cerevisiae SU50 strain CRC Calado, BS Ferreira, MMR da Fonseca, JMS Cabral, LP Fonseca Journal of biotechnology 109 (1-2), 147-158, 2004 | 42 | 2004 |
In situ near-infrared (NIR) versus high-throughput mid-infrared (MIR) spectroscopy to monitor biopharmaceutical production KC Sales, F Rosa, PN Sampaio, LP Fonseca, MB Lopes, CRC Calado Applied spectroscopy 69 (6), 760-772, 2015 | 41 | 2015 |
High‐throughput analysis of the plasmid bioproduction process in Escherichia coli by FTIR spectroscopy T Scholz, VV Lopes, CRC Calado Biotechnology and Bioengineering 109 (9), 2279-2285, 2012 | 33 | 2012 |
Towards a cost effective strategy for cutinase production by a recombinant Saccharomyces cerevisiae: strain physiological aspects BS Ferreira, CRC Calado, F Van Keulen, LP Fonseca, JMS Cabral, ... Applied microbiology and biotechnology 61, 69-76, 2003 | 32 | 2003 |
Micro-analytical GO/HRP bioreactor for glucose determination and bioprocess monitoring V Vojinović, CR Calado, AI Silva, M Mateus, JMS Cabral, LP Fonseca Biosensors and Bioelectronics 20 (10), 1955-1961, 2005 | 31 | 2005 |
Infection biomarkers based on metabolomics R Araújo, LFN Bento, TAH Fonseca, CP Von Rekowski, BR da Cunha, ... Metabolites 12 (2), 92, 2022 | 28 | 2022 |
Characterization of gastric cells infection by diverse Helicobacter pylori strains through Fourier-transform infrared spectroscopy V Marques, B Cunha, A Couto, P Sampaio, LP Fonseca, S Aleixo, ... Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 210, 193-202, 2019 | 27 | 2019 |
Optimization of the culture medium composition using response surface methodology for new recombinant cyprosin B production in bioreactor for cheese production PN Sampaio, CRC Calado, L Sousa, DC Bressler, MS Pais, LP Fonseca European Food Research and Technology 231, 339-346, 2010 | 27 | 2010 |
In situ NIR spectroscopy monitoring of plasmid production processes: effect of producing strain, medium composition and the cultivation strategy MB Lopes, GAL Gonçalves, D Felício‐Silva, KLJ Prather, GA Monteiro, ... Journal of Chemical Technology & Biotechnology 90 (2), 255-261, 2015 | 26 | 2015 |
Metabolic fingerprinting with Fourier-transform infrared (FTIR) spectroscopy: towards a high-throughput screening assay for antibiotic discovery and mechanism-of-action elucidation B Ribeiro da Cunha, LP Fonseca, CRC Calado Metabolites 10 (4), 145, 2020 | 25 | 2020 |
Simultaneous elucidation of antibiotic mechanism of action and potency with high-throughput Fourier-transform infrared (FTIR) spectroscopy and machine learning B Ribeiro da Cunha, LP Fonseca, CRC Calado Applied Microbiology and Biotechnology 105, 1269-1286, 2021 | 24 | 2021 |
Proteomics for biomarker discovery for diagnosis and prognosis of kidney transplantation rejection LM Ramalhete, R Araújo, A Ferreira, CRC Calado Proteomes 10 (3), 24, 2022 | 23 | 2022 |
A comprehensive high-throughput FTIR spectroscopy-based method for evaluating the transfection event: estimating the transfection efficiency and extracting associated metabolic … F Rosa, KC Sales, BR Cunha, A Couto, MB Lopes, CRC Calado Analytical and bioanalytical chemistry 407, 8097-8108, 2015 | 23 | 2015 |
Recombinant Saccharomyces cerevisiae strain triggers acetate production to fuel biosynthetic pathways BS Ferreira, CRC Calado, F van Keulen, LP Fonseca, JMS Cabral, ... Journal of biotechnology 109 (1-2), 159-167, 2004 | 23 | 2004 |