Decreased histone deacetylase activity in chronic obstructive pulmonary disease K Ito, M Ito, WM Elliott, B Cosio, G Caramori, OM Kon, A Barczyk, ... New England Journal of Medicine 352 (19), 1967-1976, 2005 | 1244 | 2005 |
Histone deacetylase 2–mediated deacetylation of the glucocorticoid receptor enables NF-κB suppression K Ito, S Yamamura, S Essilfie-Quaye, B Cosio, M Ito, PJ Barnes, ... The Journal of experimental medicine 203 (1), 7-13, 2006 | 808 | 2006 |
A molecular mechanism of action of theophylline: Induction of histone deacetylase activity to decrease inflammatory gene expression K Ito, S Lim, G Caramori, B Cosio, KF Chung, IM Adcock, PJ Barnes Proceedings of the National Academy of Sciences 99 (13), 8921-8926, 2002 | 670 | 2002 |
Theophylline restores histone deacetylase activity and steroid responses in COPD macrophages BG Cosio, L Tsaprouni, K Ito, E Jazrawi, IM Adcock, PJ Barnes The Journal of experimental medicine 200 (5), 689-695, 2004 | 599 | 2004 |
Increased expression of transient receptor potential vanilloid-1 in airway nerves of chronic cough DA Groneberg, A Niimi, QT Dinh, B Cosio, M Hew, A Fischer, KF Chung American journal of respiratory and critical care medicine 170 (12), 1276-1280, 2004 | 506 | 2004 |
Consensus document on the overlap phenotype COPD–asthma in COPD JJ Soler-Cataluna, B Cosío, JL Izquierdo, JL López-Campos, JM Marín, ... Archivos de Bronconeumología (English Edition) 48 (9), 331-337, 2012 | 398 | 2012 |
Defining the asthma-COPD overlap syndrome in a COPD cohort BG Cosio, JB Soriano, JL López-Campos, M Calle-Rubio, ... Chest 149 (1), 45-52, 2016 | 330 | 2016 |
Spanish Guidelines for Management of Chronic Obstructive Pulmonary Disease (GesEPOC) 2017. Pharmacological Treatment of Stable Phase. M Miravitlles, JJ Soler-Cataluña, M Calle, J Molina, P Almagro, ... Archivos de bronconeumologia 53 (6), 324-335, 2017 | 329 | 2017 |
Histone acetylase and deacetylase activity in alveolar macrophages and blood mononocytes in asthma BG Cosío, B Mann, K Ito, E Jazrawi, PJ Barnes, KF Chung, IM Adcock American journal of respiratory and critical care medicine 170 (2), 141-147, 2004 | 311 | 2004 |
Validation of the ‘Test of the Adherence to Inhalers’(TAI) for asthma and COPD patients V Plaza, C Fernández-Rodríguez, C Melero, BG Cosío, LM Entrenas, ... Journal of aerosol medicine and pulmonary drug delivery 29 (2), 142-152, 2016 | 306 | 2016 |
Prevalence and determinants of COPD in Spain: EPISCAN II JB Soriano, I Alfageme, M Miravitlles, P de Lucas, JJ Soler-Cataluna, ... Archivos de bronconeumologia 57 (1), 61-69, 2021 | 258 | 2021 |
Eosinophilic and noneosinophilic asthma: an expert consensus framework to characterize phenotypes in a global real-life severe asthma cohort LG Heaney, LP de Llano, M Al-Ahmad, V Backer, J Busby, GW Canonica, ... Chest 160 (3), 814-830, 2021 | 243 | 2021 |
Endobronchial hamartoma BG Cosio, V Villena, J Echave-Sustaeta, E de Miguel, J Alfaro, ... Chest 122 (1), 202-205, 2002 | 237 | 2002 |
[Translated article] Spanish COPD guidelines (GesEPOC) 2021: Updated pharmacological treatment of stable COPD M Miravitlles, M Calle, J Molina, P Almagro, JT Gómez, JA Trigueros, ... Archivos de bronconeumologia 58 (1), T69-T81, 2022 | 205 | 2022 |
Low-dose theophylline enhances the anti-inflammatory effects of steroids during exacerbations of COPD BG Cosio, A Iglesias, A Rios, A Noguera, E Sala, K Ito, PJ Barnes, ... Thorax 64 (5), 424-429, 2009 | 192 | 2009 |
Nature of airway inflammation and remodeling in chronic cough A Niimi, A Torrego, AG Nicholson, BG Cosio, TB Oates, KF Chung Journal of allergy and clinical immunology 116 (3), 565-570, 2005 | 188 | 2005 |
p65-activated histone acetyltransferase activity is repressed by glucocorticoids: mifepristone fails to recruit HDAC2 to the p65-HAT complex K Ito, E Jazrawi, B Cosio, PJ Barnes, IM Adcock Journal of Biological Chemistry 276 (32), 30208-30215, 2001 | 187 | 2001 |
Prevalence of persistent blood eosinophilia: relation to outcomes in patients with COPD C Casanova, BR Celli, JP de-Torres, C Martínez-Gonzalez, BG Cosio, ... European Respiratory Journal 50 (5), 2017 | 184 | 2017 |
Consensus on the asthma–COPD overlap (ACO) between the Spanish COPD guidelines (GesEPOC) and the Spanish guidelines on the management of asthma (GEMA) V Plaza, F Álvarez, M Calle, C Casanova, BG Cosío, A López-Viña, ... Archivos de Bronconeumología (English Edition) 53 (8), 443-449, 2017 | 179* | 2017 |
Guía española de la enfermedad pulmonar obstructiva crónica (GesEPOC) 2017. Tratamiento farmacológico en fase estable M Miravitlles, JJ Soler-Cataluña, M Calle, J Molina, P Almagro, ... Archivos de Bronconeumología 53 (6), 324-335, 2017 | 177 | 2017 |