| The Opisthorchis viverrini genome provides insights into life in the bile duct ND Young, N Nagarajan, SJ Lin, PK Korhonen, AR Jex, RS Hall, ... Nature communications 5 (1), 4378, 2014 | 190 | 2014 |
| Specialized insulin is used for chemical warfare by fish-hunting cone snails H Safavi-Hemami, J Gajewiak, S Karanth, SD Robinson, B Ueberheide, ... Proceedings of the National Academy of Sciences 112 (6), 1743-1748, 2015 | 185 | 2015 |
| Pain therapeutics from cone snail venoms: From Ziconotide to novel non-opioid pathways H Safavi-Hemami, SE Brogan, BM Olivera Journal of proteomics 190, 12-20, 2019 | 147 | 2019 |
| Diversity of conotoxin gene superfamilies in the venomous snail, Conus victoriae SD Robinson, H Safavi-Hemami, LD McIntosh, AW Purcell, RS Norton, ... PloS one 9 (2), e87648, 2014 | 145 | 2014 |
| A minimized human insulin-receptor-binding motif revealed in a Conus geographus venom insulin JG Menting, J Gajewiak, CA MacRaild, DHC Chou, MM Disotuar, ... Nature structural & molecular biology 23 (10), 916-920, 2016 | 95 | 2016 |
| Hormone-like peptides in the venoms of marine cone snails SD Robinson, Q Li, PK Bandyopadhyay, J Gajewiak, M Yandell, ... General and comparative endocrinology 244, 11-18, 2017 | 77 | 2017 |
| Combined proteomic and transcriptomic interrogation of the venom gland of Conus geographus uncovers novel components and functional compartmentalization H Safavi-Hemami, H Hu, DG Gorasia, PK Bandyopadhyay, PD Veith, ... Molecular & cellular proteomics 13 (4), 938-953, 2014 | 70 | 2014 |
| Insights into the origins of fish hunting in venomous cone snails from studies of Conus tessulatus JW Aman, JS Imperial, B Ueberheide, MM Zhang, M Aguilar, D Taylor, ... Proceedings of the National Academy of Sciences 112 (16), 5087-5092, 2015 | 69 | 2015 |
| Fish-hunting cone snail venoms are a rich source of minimized ligands of the vertebrate insulin receptor P Ahorukomeye, MM Disotuar, J Gajewiak, S Karanth, M Watkins, ... Elife 8, e41574, 2019 | 63 | 2019 |
| Venom insulins of cone snails diversify rapidly and track prey taxa H Safavi-Hemami, A Lu, Q Li, AE Fedosov, J Biggs, P Showers Corneli, ... Molecular biology and evolution 33 (11), 2924-2934, 2016 | 59 | 2016 |
| A structurally minimized yet fully active insulin based on cone-snail venom insulin principles X Xiong, JG Menting, MM Disotuar, NA Smith, CA Delaine, G Ghabash, ... Nature structural & molecular biology 27 (7), 615-624, 2020 | 58* | 2020 |
| Rapid expansion of the protein disulfide isomerase gene family facilitates the folding of venom peptides H Safavi-Hemami, Q Li, RL Jackson, AS Song, W Boomsma, ... Proceedings of the National Academy of Sciences 113 (12), 3227-3232, 2016 | 54 | 2016 |
| Specialisation of the venom gland proteome in predatory cone snails reveals functional diversification of the conotoxin biosynthetic pathway H Safavi-Hemami, WA Siero, DG Gorasia, ND Young, D MacMillan, ... Journal of proteome research 10 (9), 3904-3919, 2011 | 52 | 2011 |
| Modulation of conotoxin structure and function is achieved through a multienzyme complex in the venom glands of cone snails H Safavi-Hemami, DG Gorasia, AM Steiner, NA Williamson, JA Karas, ... Journal of Biological Chemistry 287 (41), 34288-34303, 2012 | 48 | 2012 |
| Identification of Conus peptidylprolyl cis-trans isomerases (PPIases) and assessment of their role in the oxidative folding of conotoxins H Safavi-Hemami, G Bulaj, BM Olivera, NA Williamson, AW Purcell Journal of Biological Chemistry 285 (17), 12735-12746, 2010 | 46 | 2010 |
| Pancreatic beta cells are highly susceptible to oxidative and ER stresses during the development of diabetes DG Gorasia, NL Dudek, PD Veith, R Shankar, H Safavi-Hemami, ... Journal of Proteome Research 14 (2), 688-699, 2015 | 45 | 2015 |
| Proteomic interrogation of venom delivery in marine cone snails: novel insights into the role of the venom bulb H Safavi-Hemami, ND Young, NA Williamson, AW Purcell Journal of proteome research 9 (11), 5610-5619, 2010 | 45 | 2010 |
| A prominent role of PDIA6 in processing of misfolded proinsulin DG Gorasia, NL Dudek, H Safavi-Hemami, RA Perez, RB Schittenhelm, ... Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1864 (6), 715-723, 2016 | 41 | 2016 |
| Divergence of the Venom Exogene Repertoire in Two Sister Species of Turriconus Q Li, N Barghi, A Lu, AE Fedosov, PK Bandyopadhyay, AO Lluisma, ... Genome biology and evolution 9 (9), 2211-2225, 2017 | 38 | 2017 |
| Discovery by proteogenomics and characterization of an RF-amide neuropeptide from cone snail venom SD Robinson, H Safavi-Hemami, S Raghuraman, JS Imperial, ... Journal of proteomics 114, 38-47, 2015 | 38 | 2015 |