Active migration and passive transport of malaria parasites RG Douglas, R Amino, P Sinnis, F Frischknecht Trends in parasitology 31 (8), 357-362, 2015 | 100 | 2015 |
Investigating the domain specificity of phosphinic inhibitors RXPA380 and RXP407 in angiotensin-converting enzyme WL Kröger, RG Douglas, HG O’Neill, V Dive, ED Sturrock Biochemistry 48 (35), 8405-8412, 2009 | 57 | 2009 |
Fragment-based design for the development of N-domain-selective angiotensin-1-converting enzyme inhibitors RG Douglas, RK Sharma, G Masuyer, L Lubbe, I Zamora, KR Acharya, ... Clinical science 126 (4), 305-313, 2014 | 52 | 2014 |
Inter-subunit interactions drive divergent dynamics in mammalian and Plasmodium actin filaments RG Douglas, P Nandekar, JE Aktories, H Kumar, R Weber, JM Sattler, ... PLoS biology 16 (7), e2005345, 2018 | 45 | 2018 |
Structural basis of Ac-SDKP hydrolysis by Angiotensin-I converting enzyme G Masuyer, RG Douglas, ED Sturrock, KR Acharya Scientific reports 5, 13742, 2015 | 29 | 2015 |
Kinetic and structural characterization of amyloid‐β peptide hydrolysis by human angiotensin‐1‐converting enzyme KM Larmuth, G Masuyer, RG Douglas, SL Schwager, KR Acharya, ... The FEBS Journal 283 (6), 1060-1076, 2016 | 24 | 2016 |
Screening for potential prophylactics targeting sporozoite motility through the skin RG Douglas, M Reinig, M Neale, F Frischknecht Malaria journal 17 (1), 319, 2018 | 22 | 2018 |
A novel angiotensin I-converting enzyme mutation (S333W) impairs N-domain enzymatic cleavage of the anti-fibrotic peptide, AcSDKP SM Danilov, MS Wade, SL Schwager, RG Douglas, AB Nesterovitch, ... PLoS One 9 (2), e88001, 2014 | 22 | 2014 |
A small mitochondrial protein present in myzozoans is essential for malaria transmission D Klug, GR Mair, F Frischknecht, RG Douglas Open biology 6 (4), 160034, 2016 | 21 | 2016 |
Divergent Plasmodium actin residues are essential for filament localization, mosquito salivary gland invasion and malaria transmission M Yee, T Walther, F Frischknecht, RG Douglas PLoS pathogens 18 (8), e1010779, 2022 | 16 | 2022 |
Antifibrotic peptide N-acetyl-Ser-Asp-Lys-Pro (Ac-SDKP): Opportunities for angiotensin-converting enzyme inhibitor design. RG Douglas, MR Ehlers, ED Sturrock Clinical & Experimental Pharmacology & Physiology 40 (8), 2013 | 13 | 2013 |
New ketomethylene inhibitor analogues: synthesis and assessment of structural determinants for N-domain selective inhibition of angiotensin-converting enzyme RK Sharma, RG Douglas, S Louw, K Chibale, ED Sturrock Biological Chemistry 393 (6), 485-493, 2012 | 13 | 2012 |
The dynamic nonprime binding of sampatrilat to the C-domain of angiotensin-converting enzyme RK Sharma, M Espinoza-Moraga, H Poblete, RG Douglas, ED Sturrock, ... Journal of Chemical Information and Modeling 56 (12), 2486-2494, 2016 | 12 | 2016 |
Vasopeptidase inhibition—Solving the cardiovascular puzzle? RG Douglas, MRW Ehlers, ED Sturrock Drugs of the Future 36 (1), 33, 2011 | 5 | 2011 |
Cytoskeleton organization in formation and motility of apicomplexan parasites RG Douglas, RW Moon, F Frischknecht Annual Review of Microbiology 78, 2024 | 3 | 2024 |
Characterization of angiotensin I-converting enzyme N-domain selectivity using positional-scanning combinatorial libraries of fluorescence resonance energy transfer peptides PA Bersanetti, RA Sabatini, BS Matos, RG Douglas, A Nchinda, ... Biological Chemistry 393 (12), 1547-1554, 2012 | 3 | 2012 |
The 2001 uses of GFP: A review of “Illuminating Disease” RG Douglas, F Frischknecht | 1 | 2015 |
Structure-based design of domain-selective angiotensin-converting enzyme inhibitors RG Douglas, ED Sturrock Drug Discovery in Africa: Impacts of Genomics, Natural Products, Traditional …, 2012 | 1 | 2012 |
Molecular architecture of glideosome and nuclear F-actin in Plasmodium falciparum V Pražák, D Vasishtan, K Grünewald, RG Douglas, JL Ferreira bioRxiv, 2024.04. 22.590301, 2024 | | 2024 |
Angiotensin I-converting enzyme RG Douglas, ED Sturrock Encyclopedia of Metalloproteins, 63-68, 2013 | | 2013 |