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Amy K Reeve
Amy K Reeve
Adresse e-mail validée de ncl.ac.uk
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High levels of mitochondrial DNA deletions in substantia nigra neurons in aging and Parkinson disease
A Bender, KJ Krishnan, CM Morris, GA Taylor, AK Reeve, RH Perry, ...
Nature genetics 38 (5), 515-517, 2006
18372006
Ageing and Parkinson's disease: why is advancing age the biggest risk factor?
A Reeve, E Simcox, D Turnbull
Ageing research reviews 14, 19-30, 2014
11122014
What causes mitochondrial DNA deletions in human cells?
KJ Krishnan, AK Reeve, DC Samuels, PF Chinnery, JK Blackwood, ...
Nature genetics 40 (3), 275-279, 2008
4722008
Mitochondrial DNA deletions and neurodegeneration in multiple sclerosis
GR Campbell, I Ziabreva, AK Reeve, KJ Krishnan, R Reynolds, O Howell, ...
Annals of neurology 69 (3), 481-492, 2011
4442011
Mitochondrial DNA and disease
LC Greaves, AK Reeve, RW Taylor, DM Turnbull
The Journal of pathology 226 (2), 274-286, 2012
4032012
Mitochondrial dysfunction in Parkinson’s disease—cause or consequence?
C Chen, DM Turnbull, AK Reeve
Biology 8 (2), 38, 2019
2652019
Aggregated α-synuclein and complex I deficiency: exploration of their relationship in differentiated neurons
AK Reeve, MHR Ludtmann, PR Angelova, EM Simcox, MH Horrocks, ...
Cell death & disease 6 (7), e1820-e1820, 2015
1952015
Mitochondrial DNA mutations in disease, aging, and neurodegeneration
AK Reeve, KJ Krishnan, D Turnbull
Annals of the New York Academy of Sciences 1147 (1), 21-29, 2008
1842008
Nature of mitochondrial DNA deletions in substantia nigra neurons
AK Reeve, KJ Krishnan, JL Elson, CM Morris, A Bender, RN Lightowlers, ...
The American Journal of Human Genetics 82 (1), 228-235, 2008
1662008
The rise and rise of mitochondrial DNA mutations
C Lawless, L Greaves, AK Reeve, DM Turnbull, AE Vincent
Open biology 10 (5), 200061, 2020
1432020
Mitochondrial dysfunction within the synapses of substantia nigra neurons in Parkinson’s disease
AK Reeve, JP Grady, EM Cosgrave, E Bennison, C Chen, ...
npj Parkinson's Disease 4 (1), 9, 2018
1162018
Cerebellar ataxia in patients with mitochondrial DNA disease: a molecular clinicopathological study
NZ Lax, PD Hepplewhite, AK Reeve, V Nesbitt, R McFarland, E Jaros, ...
Journal of Neuropathology & Experimental Neurology 71 (2), 148-161, 2012
1152012
OPA1 mutations cause cytochrome c oxidase deficiency due to loss of wild-type mtDNA molecules
P Yu-Wai-Man, KS Sitarz, DC Samuels, PG Griffiths, AK Reeve, LA Bindoff, ...
Human molecular genetics 19 (15), 3043-3052, 2010
1102010
The ageing mitochondrial genome
KJ Krishnan, LC Greaves, AK Reeve, D Turnbull
Nucleic acids research 35 (22), 7399-7405, 2007
1092007
The impact of pathogenic mitochondrial DNA mutations on substantia nigra neurons
A Reeve, M Meagher, N Lax, E Simcox, P Hepplewhite, E Jaros, ...
Journal of Neuroscience 33 (26), 10790-10801, 2013
1042013
3D neuronal mitochondrial morphology in axons, dendrites, and somata of the aging mouse hippocampus
J Faitg, C Lacefield, T Davey, K White, R Laws, S Kosmidis, AK Reeve, ...
Cell reports 36 (6), 2021
902021
Mitochondrial dysfunction impairs osteogenesis, increases osteoclast activity, and accelerates age related bone loss
PF Dobson, EP Dennis, D Hipps, A Reeve, A Laude, C Bradshaw, ...
Scientific reports 10 (1), 11643, 2020
882020
Mitochondrial DNA mutations and aging
KJ Krishnan, LC Greaves, AK Reeve, DM Turnbull
Annals of the New York Academy of Sciences 1100 (1), 227-240, 2007
872007
Age related mitochondrial degenerative disorders in humans
AK Reeve, KJ Krishnan, DM Turnbull
Biotechnology Journal: Healthcare Nutrition Technology 3 (6), 750-756, 2008
832008
Sensory neuronopathy in patients harbouring recessive polymerase γ mutations
NZ Lax, RG Whittaker, PD Hepplewhite, AK Reeve, EL Blakely, E Jaros, ...
Brain 135 (1), 62-71, 2012
782012
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