| A tryptoline ring‐distortion strategy leads to complex and diverse biologically active molecules from the indole alkaloid yohimbine NG Paciaroni, R Ratnayake, JH Matthews, VM Norwood IV, AC Arnold, ... Chemistry–A European Journal 23 (18), 4327-4335, 2017 | 81 | 2017 |
| Bromophenazine derivatives with potent inhibition, dispersion and eradication activities against Staphylococcus aureus biofilms AT Garrison, F Bai, Y Abouelhassan, NG Paciaroni, S Jin, RW Huigens III Rsc Advances 5 (2), 1120-1124, 2015 | 52 | 2015 |
| Beyond protein binding: recent advances in screening DNA-encoded libraries T Kodadek, NG Paciaroni, M Balzarini, P Dickson Chemical Communications 55 (89), 13330-13341, 2019 | 48 | 2019 |
| Solid-phase synthesis of DNA-encoded libraries via an “aldehyde explosion” strategy NG Paciaroni, JM Ndungu, T Kodadek Chemical Communications 56 (34), 4656-4659, 2020 | 37 | 2020 |
| Re-engineering of yohimbine’s biological activity through ring distortion: identification and structure–activity relationships of a new class of antiplasmodial agents NG Paciaroni, DL Perry, VM Norwood IV, C Murillo-Solano, J Collins, ... ACS infectious diseases 6 (2), 159-167, 2020 | 24 | 2020 |
| Yohimbine as a starting point to access diverse natural product-like agents with re-programmed activities against cancer-relevant GPCR targets NG Paciaroni, VM Norwood IV, R Ratnayake, H Luesch, RW Huigens III Bioorganic & medicinal chemistry 28 (14), 115546, 2020 | 23 | 2020 |
| Synthesis and Screening of a DNA‐Encoded Library of Non‐Peptidic Macrocycles E Koesema, A Roy, NG Paciaroni, C Coito, M Tokmina‐Roszyk, ... Angewandte Chemie 134 (18), e202116999, 2022 | 22 | 2022 |
| VM t. Norwood, AC Arnold, LH Dang, H. Luesch, RW Huigens 3rd NG Paciaroni, R Ratnayake, JH Matthews Chem.–Eur. J 23, 4327-4335, 2017 | 6 | 2017 |
| Rapid Synthesis of Phenazine-1-Carboxylic Acid Derived SmallMolecules from Diverse Anilines: Privileged Structures for Discovery NG Paciaroni, NV Borrero, JR Rocca, RW Huigens III Res Rev J Med Org Chem 2 (1), 67-76, 2015 | 6 | 2015 |
| First-in-class multifunctional TYMS nonclassical antifolate inhibitor with potent in vivo activity that prolongs survival MV Guijarro, PC Kellish, PE Dib, NG Paciaroni, A Nawab, J Andring, ... JCI insight 8 (10), 2023 | 3 | 2023 |
| Microwave-enhanced, stereospecific ring-closure of medium-ring cyanamide ethers to yohimbine NG Paciaroni, VM Norwood IV, DE Garcia, RW Huigens III Tetrahedron Letters 60 (17), 1182-1185, 2019 | 2 | 2019 |
| Analogs of yohimbine and uses thereof RW HUIGENS III, NG PACIARONI | 1 | 2017 |
| Back Cover: A Tryptoline Ring‐Distortion Strategy Leads to Complex and Diverse Biologically Active Molecules from the Indole Alkaloid Yohimbine (Chem. Eur. J. 18/2017) NG Paciaroni, R Ratnayake, JH Matthews, VM Norwood IV, AC Arnold, ... Chemistry–A European Journal 23 (18), 4463-4463, 2017 | 1 | 2017 |
| Identification and characterization of a nonbiological small-molecular mimic of a Zika virus conformational neutralizing epitope PMS Castanha, PJ McEnaney, Y Park, A Bouwer, EJF Chaves, RD Lins, ... Proceedings of the National Academy of Sciences 121 (21), e2312755121, 2024 | | 2024 |
| First in class multifunctional non classical antifolates inhibits thymidylate synthase and extends survival in pancreatic cancer model MV Guijarro, PC Kellish, PE Dib, NG Paciaroni, A Nawab, J Andring, ... Cancer Research 82 (12_Supplement), 4055-4055, 2022 | | 2022 |
| Analogs of yohimbine and uses thereof RW Huigens III, NG Paciaroni, H Luesch US Patent 11,242,331, 2022 | | 2022 |
| Ring Distortion of Yohimbine Leads to Diverse Biological Discoveries NG Paciaroni University of Florida, 2018 | | 2018 |
| Research & Reviews: Journal of Medicinal & Organic Chemistry NG Paciaroni, NV Borrero, JR Rocca, RWH III | | |
