Fasting cycles retard growth of tumors and sensitize a range of cancer cell types to chemotherapy C Lee, L Raffaghello, S Brandhorst, FM Safdie, G Bianchi, ... Science translational medicine 4 (124), 124ra27-124ra27, 2012 | 864 | 2012 |
Starvation-dependent differential stress resistance protects normal but not cancer cells against high-dose chemotherapy L Raffaghello, C Lee, FM Safdie, M Wei, F Madia, G Bianchi, VD Longo Proceedings of the National Academy of Sciences 105 (24), 8215-8220, 2008 | 700 | 2008 |
The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance C Lee, J Zeng, BG Drew, T Sallam, A Martin-Montalvo, J Wan, SJ Kim, ... Cell metabolism 21 (3), 443-454, 2015 | 666 | 2015 |
Fasting and cancer treatment in humans: A case series report FM Safdie, T Dorff, D Quinn, L Fontana, M Wei, C Lee, P Cohen, ... Aging (Albany NY) 1 (12), 988, 2009 | 535 | 2009 |
Fasting vs dietary restriction in cellular protection and cancer treatment: from model organisms to patients C Lee, VD Longo Oncogene 30 (30), 3305-3316, 2011 | 440 | 2011 |
Fasting-mimicking diet reduces HO-1 to promote T cell-mediated tumor cytotoxicity S Di Biase, C Lee, S Brandhorst, B Manes, R Buono, CW Cheng, ... Cancer cell 30 (1), 136-146, 2016 | 400 | 2016 |
Reduced levels of IGF-I mediate differential protection of normal and cancer cells in response to fasting and improve chemotherapeutic index C Lee, FM Safdie, L Raffaghello, M Wei, F Madia, E Parrella, D Hwang, ... Cancer research 70 (4), 1564-1572, 2010 | 371 | 2010 |
Humanin: a harbinger of mitochondrial-derived peptides? C Lee, K Yen, P Cohen Trends in Endocrinology & Metabolism 24 (5), 222-228, 2013 | 315 | 2013 |
Fasting enhances the response of glioma to chemo-and radiotherapy F Safdie, S Brandhorst, M Wei, W Wang, C Lee, S Hwang, PS Conti, ... Public Library of Science 7 (9), e44603, 2012 | 268 | 2012 |
Naturally occurring mitochondrial-derived peptides are age-dependent regulators of apoptosis, insulin sensitivity, and inflammatory markers LJ Cobb, C Lee, J Xiao, K Yen, RG Wong, HK Nakamura, HH Mehta, ... Aging (Albany NY) 8 (4), 796, 2016 | 253 | 2016 |
The mitochondrial-encoded peptide MOTS-c translocates to the nucleus to regulate nuclear gene expression in response to metabolic stress KH Kim, JM Son, BA Benayoun, C Lee Cell metabolism 28 (3), 516-524. e7, 2018 | 245 | 2018 |
The emerging role of the mitochondrial-derived peptide humanin in stress resistance K Yen, C Lee, H Mehta, P Cohen Journal of molecular endocrinology 50 (1), R11, 2013 | 236 | 2013 |
Dietary restriction with and without caloric restriction for healthy aging C Lee, V Longo F1000Research 5, 2016 | 235 | 2016 |
MOTS-c: a novel mitochondrial-derived peptide regulating muscle and fat metabolism C Lee, KH Kim, P Cohen Free Radical Biology and Medicine 100, 182-187, 2016 | 169 | 2016 |
Nutrition and fasting mimicking diets in the prevention and treatment of autoimmune diseases and immunosenescence IY Choi, C Lee, VD Longo Molecular and cellular endocrinology 455, 4-12, 2017 | 167 | 2017 |
MOTS-c is an exercise-induced mitochondrial-encoded regulator of age-dependent physical decline and muscle homeostasis JC Reynolds, RW Lai, JST Woodhead, JH Joly, CJ Mitchell, ... Nature communications 12 (1), 470, 2021 | 137 | 2021 |
Mitochondrial-derived peptides in energy metabolism TL Merry, A Chan, JST Woodhead, JC Reynolds, H Kumagai, SJ Kim, ... American Journal of Physiology-Endocrinology and Metabolism 319 (4), E659-E666, 2020 | 109 | 2020 |
IGF‐I regulates the age‐dependent signaling peptide humanin C Lee, J Wan, B Miyazaki, Y Fang, J Guevara‐Aguirre, K Yen, V Longo, ... Aging Cell 13 (5), 958-961, 2014 | 88 | 2014 |
Starvation, detoxification, and multidrug resistance in cancer therapy C Lee, L Raffaghello, VD Longo Drug Resistance Updates 15 (1-2), 114-122, 2012 | 87 | 2012 |
Mitochondria: multifaceted regulators of aging JM Son, C Lee BMB reports 52 (1), 13, 2019 | 77 | 2019 |