Kalet Leon Monzon

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Jorge CarneiroAdresse e-mail validée de igc.gulbenkian.pt
Tania Crombet Ramos, MD, PhDClinical Research Director, Center of Molecular Immunology, Havana, CubaAdresse e-mail validée de cim.sld.cu
Karina Garcia-MartinezCenter of Molecular ImmunologyAdresse e-mail validée de cim.sld.cu
tania carmenateSenior Researcher and Group Leader, Centro de Inmunologia MolecularAdresse e-mail validée de cim.sld.cu
Jose FaroAssociate Professor of immunology, University of VigoAdresse e-mail validée de uvigo.es
Luis GracaIMM, Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de LisboaAdresse e-mail validée de fm.ul.pt
Roberto MuletFacultad de Fisica, Universidad de la HabanaAdresse e-mail validée de fisica.uh.cu
Ernesto Moreno FriasUniversidad de Medellín, ColombiaAdresse e-mail validée de udemedellin.edu.co
Pedro A ValienteDonnelly Center for Cellular and Biomolecular Research, Faculty of Medicine, University of TorontoAdresse e-mail validée de utoronto.ca
Gertrudis RojasSenior researcher and Head of the Protein Engineering Department, Center of Molecular ImmunologyAdresse e-mail validée de cim.sld.cu
Jorge FERNANDEZ-DE-COSSIO-DIAZUniversité Paris-Saclay, CNRS, CEA, Institut de Physique Théorique (IPhT)Adresse e-mail validée de ipht.fr
Tiago PaixaoInstituto Gulbenkian de CiênciaAdresse e-mail validée de igc.gulbenkian.pt
Jesus Corria-OsorioLICR@UNILAdresse e-mail validée de unil.ch
DR Nuno SepúlvedaCharité UniversitatsMedizin BerlinAdresse e-mail validée de lshtm.ac.uk
Amaury PupoWest Virginia UniversityAdresse e-mail validée de mail.wvu.edu
Yasset Perez-RiverolTeam Coordinator, Proteomics Resources, EMBL-EBI, UKAdresse e-mail validée de ebi.ac.uk
Mayra Ramos Suzarte, M Ramos, M R...Head Clinical Trials Department, Center of Molecular ImmunologyAdresse e-mail validée de cim.sld.cu

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Kalet Leon Monzon

Center of Molecular Immunology, Habana, Cuba

Adresse e-mail validée de cim.sld.cu

Immune Regulation Cancer Immunotherapy Cytokine Ingeniering Mathematical Modelling Bioinformatics


Titre Trier par citations Trier par année Trier par titre	Citée par Citée par	Année
Human IL-2 mutein with higher antitumor efficacy than wild type IL-2 T Carmenate, A Pacios, M Enamorado, E Moreno, K Garcia-Martínez, ... The Journal of Immunology 190 (12), 6230-6238, 2013	148	2013
When three is not a crowd: a Crossregulation Model of the dynamics and repertoire selection of regulatory CD4⁺ T cells J Carneiro, K Leon, Í Caramalho, C Van Den Dool, R Gardner, V Oliveira, ... Immunological reviews 216 (1), 48-68, 2007	101	2007
SARS-CoV-2 RBD-tetanus toxoid conjugate vaccine induces a strong neutralizing immunity in preclinical studies Y Valdes-Balbin, D Santana-Mederos, L Quintero, S Fernández, ... ACS Chemical Biology 16 (7), 1223-1233, 2021	95	2021
Tolerance and immunity in a mathematical model of T-cell mediated suppression K León, A Lage, J Carneiro Journal of theoretical biology 225 (1), 107-126, 2003	91	2003
Modelling T-cell-mediated suppression dependent on interactions in multicellular conjugates K Leon, R Perez, A Lage, J Carneiro Journal of Theoretical Biology 207 (2), 231-254, 2000	89	2000
A general mathematical framework to model generation structure in a population of asynchronously dividing cells K León, J Faro, J Carneiro Journal of theoretical biology 229 (4), 455-476, 2004	77	2004
Immunological self-tolerance: Lessons from mathematical modeling J Carneiro, T Paixão, D Milutinovic, J Sousa, K Leon, R Gardner, J Faro Journal of Computational and Applied Mathematics 184 (1), 77-100, 2005	70	2005
Molecular aspects concerning the use of the SARS-CoV-2 receptor binding domain as a target for preventive vaccines Y Valdes-Balbin, D Santana-Mederos, F Paquet, S Fernandez, Y Climent, ... ACS central science 7 (5), 757-767, 2021	62	2021
Blocking IL-2 signal in vivo with an IL-2 antagonist reduces tumor growth through the control of regulatory T cells T Carmenate, Y Ortíz, M Enamorado, K García-Martínez, J Avellanet, ... The Journal of Immunology 200 (10), 3475-3484, 2018	49	2018
IL-2 derivative polypeptides KL Monzón, TC Portilla, SP Rodriguez, NME Escalona, ABL Dávila US Patent 9,206,243, 2015	49	2015
Autoimmunization to epidermal growth factor, a component of the immunological homunculus G Gonzalez, E Montero, K Leon, IR Cohen, A Lage Autoimmunity reviews 1 (1-2), 89-95, 2002	49	2002
Inverse correlation between the incidences of autoimmune disease and infection predicted by a model of T cell mediated tolerance K León, J Faro, A Lage, J Carneiro Journal of Autoimmunity 22 (1), 31-42, 2004	46	2004
Use of a humanized anti-CD6 monoclonal antibody (itolizumab) in elderly patients with moderate COVID-19 Y Díaz, M Ramos-Suzarte, Y Martín, NA Calderón, W Santiago, O Viñet, ... Gerontology 66 (6), 553-561, 2020	39	2020
How regulatory CD25+ CD4+ T cells impinge on tumor immunobiology? On the existence of two alternative dynamical classes of tumors K Leon, K Garcia, J Carneiro, A Lage Journal of theoretical biology 247 (1), 122-137, 2007	39	2007
An anti-CD6 monoclonal antibody (itolizumab) reduces circulating IL-6 in severe COVID-19 elderly patients D Saavedra, AL Añé-Kourí, N Sánchez, LM Filgueira, J Betancourt, ... Immunity & Ageing 17, 1-8, 2020	36	2020
Characterizing steady states of genome-scale metabolic networks in continuous cell cultures J Fernandez-de-Cossio-Diaz, K Leon, R Mulet PLoS computational biology 13 (11), e1005835, 2017	35	2017
Therapeutic approaches to target cancer stem cells A Diaz, K Leon Cancers 3 (3), 3331-3352, 2011	35	2011
Geometric and chemical patterns of interaction in protein–ligand complexes and their application in docking E Moreno, K León Proteins: Structure, Function, and Bioinformatics 47 (1), 1-13, 2002	34	2002
Deciphering the molecular bases of the biological effects of antibodies against Interleukin-2: a versatile platform for fine epitope mapping G Rojas, A Pupo, K Leon, J Avellanet, T Carmenate, S Sidhu Immunobiology 218 (1), 105-113, 2013	33	2013
How regulatory CD25+ CD4+ T cells impinge on tumor immunobiology: the differential response of tumors to therapies K Leon, K Garcia, J Carneiro, A Lage The Journal of Immunology 179 (9), 5659-5668, 2007	30	2007

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