Arid1a has context-dependent oncogenic and tumor suppressor functions in liver cancer X Sun, SC Wang, Y Wei, X Luo, Y Jia, L Li, P Gopal, M Zhu, I Nassour, ... Cancer cell 32 (5), 574-589. e6, 2017 | 263 | 2017 |
A mechanosensitive peri-arteriolar niche for osteogenesis and lymphopoiesis B Shen, A Tasdogan, JM Ubellacker, J Zhang, ED Nosyreva, L Du, ... Nature 591 (7850), 438-444, 2021 | 229 | 2021 |
Somatic mutations increase hepatic clonal fitness and regeneration in chronic liver disease M Zhu, T Lu, Y Jia, X Luo, P Gopal, L Li, M Odewole, V Renteria, ... Cell 177 (3), 608-621. e12, 2019 | 220 | 2019 |
Liver homeostasis is maintained by midlobular zone 2 hepatocytes Y Wei, YG Wang, Y Jia, L Li, J Yoon, S Zhang, Z Wang, Y Zhang, M Zhu, ... Science 371 (6532), eabb1625, 2021 | 207 | 2021 |
Dendrimer‐based lipid nanoparticles deliver therapeutic FAH mRNA to normalize liver function and extend survival in a mouse model of hepatorenal tyrosinemia type I Q Cheng, T Wei, Y Jia, L Farbiak, K Zhou, S Zhang, Y Wei, H Zhu, ... Advanced materials 30 (52), 1805308, 2018 | 202 | 2018 |
Recurrent chimeric fusion RNAs in non-cancer tissues and cells M Babiceanu, F Qin, Z Xie, Y Jia, K Lopez, N Janus, L Facemire, S Kumar, ... Nucleic acids research 44 (6), 2859-2872, 2016 | 196 | 2016 |
Intergenically spliced chimeric RNAs in cancer Y Jia, Z Xie, H Li Trends in cancer 2 (9), 475-484, 2016 | 96 | 2016 |
A mouse model with high clonal barcode diversity for joint lineage, transcriptomic, and epigenomic profiling in single cells L Li, S Bowling, SE McGeary, Q Yu, B Lemke, K Alcedo, Y Jia, X Liu, ... Cell 186 (23), 5183-5199. e22, 2023 | 81 | 2023 |
Mice with increased numbers of polyploid hepatocytes maintain regenerative capacity but develop fewer hepatocellular carcinomas following chronic liver injury YH Lin, S Zhang, M Zhu, T Lu, K Chen, Z Wen, S Wang, G Xiao, D Luo, ... Gastroenterology 158 (6), 1698-1712. e14, 2020 | 76 | 2020 |
Human hematopoietic stem cell vulnerability to ferroptosis J Zhao, Y Jia, D Mahmut, AA Deik, S Jeanfavre, CB Clish, VG Sankaran Cell 186 (4), 732-747. e16, 2023 | 72 | 2023 |
A cytoskeleton regulator AVIL drives tumorigenesis in glioblastoma Z Xie, PŁ Janczyk, Y Zhang, A Liu, X Shi, S Singh, L Facemire, K Kubow, ... Nature communications 11 (1), 3457, 2020 | 49 | 2020 |
Dual ARID1A/ARID1B loss leads to rapid carcinogenesis and disruptive redistribution of BAF complexes Z Wang, K Chen, Y Jia, JC Chuang, X Sun, YH Lin, C Celen, L Li, ... Nature cancer 1 (9), 909-922, 2020 | 48 | 2020 |
Positive selection of somatically mutated clones identifies adaptive pathways in metabolic liver disease Z Wang, S Zhu, Y Jia, Y Wang, N Kubota, N Fujiwara, R Gordillo, C Lewis, ... Cell 186 (9), 1968-1984. e20, 2023 | 44 | 2023 |
Fusion transcriptome profiling provides insights into alveolar rhabdomyosarcoma Z Xie, M Babiceanu, S Kumar, Y Jia, F Qin, FG Barr, H Li Proceedings of the National Academy of Sciences 113 (46), 13126-13131, 2016 | 43 | 2016 |
In vivo CRISPR screening identifies BAZ2 chromatin remodelers as druggable regulators of mammalian liver regeneration Y Jia, L Li, YH Lin, P Gopal, S Shen, K Zhou, X Yu, T Sharma, Y Zhang, ... Cell Stem Cell 29 (3), 372-385. e8, 2022 | 37 | 2022 |
Merkel cell polyomavirus small T antigen activates noncanonical NF-κB signaling to promote tumorigenesis J Zhao, Y Jia, S Shen, J Kim, X Wang, E Lee, I Brownell, JH Cho-Vega, ... Molecular Cancer Research 18 (11), 1623-1637, 2020 | 30 | 2020 |
A mitofusin 2/HIF1α axis sets a maturation checkpoint in regenerating skeletal muscle X Wang, Y Jia, J Zhao, NP Lesner, CJ Menezes, SD Shelton, ... The Journal of Clinical Investigation 132 (23), 2022 | 12 | 2022 |
Arid1a loss potentiates pancreatic β-cell regeneration through activation of EGF signaling C Celen, JC Chuang, S Shen, L Li, G Maggiore, Y Jia, X Luo, A Moore, ... Cell Reports 41 (5), 2022 | 11 | 2022 |
Metabolic inflexibility promotes mitochondrial health during liver regeneration X Wang, CJ Menezes, Y Jia, Y Xiao, SSK Venigalla, F Cai, MH Hsieh, ... Science 384 (6701), eadj4301, 2024 | 8 | 2024 |
Inherited blood cancer predisposition through altered transcription elongation J Zhao, LD Cato, UP Arora, EL Bao, SC Bryant, N Williams, Y Jia, ... Cell 187 (3), 642-658. e19, 2024 | 7 | 2024 |