Nuclear envelope rupture and repair during cancer cell migration CM Denais, RM Gilbert, P Isermann, AL McGregor, M te Lindert, ... Science 352 (6283), 353-358, 2016 | 1290 | 2016 |
Nuclear mechanics and mechanotransduction in health and disease P Isermann, J Lammerding Current Biology 23 (24), R1113-R1121, 2013 | 430 | 2013 |
Mutant lamins cause nuclear envelope rupture and DNA damage in skeletal muscle cells AJ Earle, TJ Kirby, GR Fedorchak, P Isermann, J Patel, S Iruvanti, ... Nature Materials 19 (4), 464-473, 2020 | 222 | 2020 |
Myopathic lamin mutations impair nuclear stability in cells and tissue and disrupt nucleo-cytoskeletal coupling M Zwerger, DE Jaalouk, ML Lombardi, P Isermann, M Mauermann, ... Human molecular genetics 22 (12), 2335-2349, 2013 | 187 | 2013 |
Design of a microfluidic device to quantify dynamic intra-nuclear deformation during cell migration through confining environments PM Davidson, J Sliz, P Isermann, C Denais, J Lammerding Integrative Biology 7 (12), 1534-1546, 2015 | 162 | 2015 |
A Chemomechanical Model for Nuclear Morphology and Stresses during Cell Transendothelial Migration X Cao, E Moeendarbary, P Isermann, PM Davidson, X Wang, MB Chen, ... Biophysical Journal 111 (7), 1541-1552, 2016 | 143 | 2016 |
Low lamin A levels enhance confined cell migration and metastatic capacity in breast cancer ES Bell, P Shah, N Zuela-Sopilniak, D Kim, AA Varlet, JLP Morival, ... Oncogene 41 (36), 4211-4230, 2022 | 82 | 2022 |
High-throughput microfluidic micropipette aspiration device to probe time-scale dependent nuclear mechanics in intact cells PM Davidson, GR Fedorchak, S Mondésert-Deveraux, ES Bell, ... Lab on a Chip 19 (21), 3652-3663, 2019 | 81 | 2019 |
Cellular and molecular remodelling of a host cell for vertical transmission of bacterial symbionts JB Luan, HW Shan, P Isermann, JH Huang, J Lammerding, SS Liu, ... Proceedings of the Royal Society B: Biological Sciences 283 (1833), 20160580, 2016 | 81 | 2016 |
Cell migration through three-dimensional confining pores: speed accelerations by deformation and recoil of the nucleus M Krause, FW Yang, M Te Lindert, P Isermann, J Schepens, RJA Maas, ... Philosophical Transactions of the Royal Society B 374 (1779), 20180225, 2019 | 76 | 2019 |
Cell migration through three-dimensional confining pores: speed accelerations by deformation and recoil of the nucleus M Krause, FW Yang, M te Lindert, P Isermann, J Schepens, RJA Maas, ... Philosophical Transactions of the Royal Society B 374 (1779), 20180225, 2019 | 76 | 2019 |
Consequences of a tight squeeze: Nuclear envelope rupture and repair P Isermann, J Lammerding Nucleus 8 (3), 268-274, 2017 | 62 | 2017 |
Assays to measure nuclear mechanics in interphase cells P Isermann, PM Davidson, JD Sliz, J Lammerding Current protocols in cell biology 56 (1), 22.16. 1-22.16. 21, 2012 | 26 | 2012 |
Lamin B2 follows lamin A/C-mediated nuclear mechanics and cancer cell invasion efficacy M Vortmeyer-Krause, M Lindert, J Riet, V Boekhorst, R Marke, R Perera, ... BioRxiv, 2020.04. 07.028969, 2020 | 21 | 2020 |
Mutant lamins cause mechanically-induced nuclear envelope rupture, DNA damage, and DNA-PK activation in muscle AJ Earle, TJ Kirby, GR Fedorchak, P Isermann, J Patel, S Iruvanti, ... BioRxiv, 364778, 2018 | 6 | 2018 |
Mechanically-induced nuclear damage and increased p53 signaling lead to myofiber dysfunction in skeletal muscle laminopathies TJ Kirby, AJ Earle, GR Fedorchak, P Isermann, J Patel, S Iruvanti, ... 9th UK Nuclear Envelope Disease and Chrmatin Organisation Meeting/3rd …, 2019 | | 2019 |
High-throughput microfluidic micropipette aspiration device to probe time-scale dependent nuclear mechanics in intact cells G FEDORCHAK, S MONDÉSERT-DEVERAUX, E BELL, P ISERMANN, ... Royal Society of Chemistry, 2019 | | 2019 |
Lamin A/C Mutations Linked to Muscular Disease Result in Mechanically‐induced, Progressive Nuclear Envelope Rupture and DNA Damage in Muscle Fibers T Kirby, A Earle, G Fedorchak, P Isermann, J Lammerding The FASEB Journal 32, 816.6-816.6, 2018 | | 2018 |
Lamin A/C mutant myonuclei experience nuclear envelope rupture and DNA damage that is reduced upon microtubule stabilization. TJ Kirby, A Earle, GR Fedorchak, P Isermann, C Brightwell, C Fry, ... MOLECULAR BIOLOGY OF THE CELL 28, 2017 | | 2017 |
Lamin mutations linked to muscular disease result in mechanically-induced, progressive nuclear envelope rupture and DNA damage in muscle fibers. A Earle, TJ Kirby, GR Fedorchak, P Isermann, J Lammerding MOLECULAR BIOLOGY OF THE CELL 28, 2017 | | 2017 |