| Obesity is associated with hypothalamic injury in rodents and humans JP Thaler, CX Yi, EA Schur, SJ Guyenet, BH Hwang, MO Dietrich, X Zhao, ... The Journal of clinical investigation 122 (1), 153, 2012 | 2008 | 2012 |
| Sirtuin 1 and sirtuin 3: physiological modulators of metabolism R Nogueiras, KM Habegger, N Chaudhary, B Finan, AS Banks, ... Physiological reviews 92 (3), 1479-1514, 2012 | 778 | 2012 |
| The fat mass and obesity associated gene (Fto) regulates activity of the dopaminergic midbrain circuitry ME Hess, S Hess, KD Meyer, LAW Verhagen, L Koch, HS Brönneke, ... Nature neuroscience 16 (8), 1042-1048, 2013 | 571 | 2013 |
| Mitofusin 2 in POMC neurons connects ER stress with leptin resistance and energy imbalance M Schneeberger, MO Dietrich, D Sebastián, M Imbernón, C Castaño, ... Cell 155 (1), 172-187, 2013 | 536 | 2013 |
| Hypothalamic POMC neurons promote cannabinoid-induced feeding M Koch, L Varela, JG Kim, JD Kim, F Hernández-Nuño, SE Simonds, ... Nature 519 (7541), 45-50, 2015 | 476 | 2015 |
| Nesfatin-1-regulated oxytocinergic signaling in the paraventricular nucleus causes anorexia through a leptin-independent melanocortin pathway Y Maejima, U Sedbazar, S Suyama, D Kohno, T Onaka, E Takano, ... Cell metabolism 10 (5), 355-365, 2009 | 422 | 2009 |
| STAT3 inhibition of gluconeogenesis is downregulated by SirT1 Y Nie, DM Erion, Z Yuan, M Dietrich, GI Shulman, TL Horvath, Q Gao Nature cell biology 11 (4), 492-500, 2009 | 398 | 2009 |
| Leptin signaling in astrocytes regulates hypothalamic neuronal circuits and feeding JG Kim, S Suyama, M Koch, S Jin, P Argente-Arizon, J Argente, ZW Liu, ... Nature neuroscience 17 (7), 908-910, 2014 | 365 | 2014 |
| Peroxisome proliferation-associated control of reactive oxygen species sets melanocortin tone and feeding in diet-induced obesity S Diano, ZW Liu, JK Jeong, MO Dietrich, HB Ruan, E Kim, S Suyama, ... Nature medicine 17 (9), 1121-1127, 2011 | 311 | 2011 |
| Mitochondrial dynamics controlled by mitofusins regulate Agrp neuronal activity and diet-induced obesity MO Dietrich, ZW Liu, TL Horvath Cell 155 (1), 188-199, 2013 | 308 | 2013 |
| Hypothalamic Agrp neurons drive stereotypic behaviors beyond feeding MO Dietrich, MR Zimmer, J Bober, TL Horvath Cell 160 (6), 1222-1232, 2015 | 295 | 2015 |
| Decreased plasma brain derived neurotrophic factor levels in unmedicated bipolar patients during manic episode R Machado-Vieira, MO Dietrich, R Leke, VH Cereser, V Zanatto, ... Biological psychiatry 61 (2), 142-144, 2007 | 292 | 2007 |
| O-GlcNAc transferase enables AgRP neurons to suppress browning of white fat HB Ruan, MO Dietrich, ZW Liu, MR Zimmer, MD Li, JP Singh, K Zhang, ... Cell 159 (2), 306-317, 2014 | 286 | 2014 |
| Hypothalamic control of energy balance: insights into the role of synaptic plasticity MO Dietrich, TL Horvath Trends in neurosciences 36 (2), 65-73, 2013 | 279 | 2013 |
| Megalin mediates the transport of leptin across the blood-CSF barrier MO Dietrich, C Spuch, D Antequera, I Rodal, JG de Yébenes, JA Molina, ... Neurobiology of aging 29 (6), 902-912, 2008 | 243 | 2008 |
| Limitations in anti-obesity drug development: the critical role of hunger-promoting neurons MO Dietrich, TL Horvath Nature Reviews Drug Discovery 11 (9), 675-691, 2012 | 238 | 2012 |
| Agrp neurons mediate Sirt1's action on the melanocortin system and energy balance: roles for Sirt1 in neuronal firing and synaptic plasticity MO Dietrich, C Antunes, G Geliang, ZW Liu, E Borok, Y Nie, AW Xu, ... The Journal of Neuroscience 30 (35), 11815-11825, 2010 | 237 | 2010 |
| Exercise-induced synaptogenesis in the hippocampus is dependent on UCP2-regulated mitochondrial adaptation MO Dietrich, ZB Andrews, TL Horvath The Journal of Neuroscience 28 (42), 10766-10771, 2008 | 214 | 2008 |
| Leptin regulates glutamate and glucose transporters in hypothalamic astrocytes E Fuente-Martín, C García-Cáceres, M Granado, ML de Ceballos, ... J Clin Invest, 2012 | 210 | 2012 |
| AgRP neurons regulate development of dopamine neuronal plasticity and nonfood-associated behaviors MO Dietrich, J Bober, JG Ferreira, LA Tellez, YS Mineur, DO Souza, ... Nature Neuroscience, 2012 | 193 | 2012 |
Tamas L. HorvathYale UniversityAdresse e-mail validée de yale.edu