Base-pair-resolution genome-wide mapping of active RNA polymerases using precision nuclear run-on (PRO-seq) DB Mahat, H Kwak, GT Booth, IH Jonkers, CG Danko, RK Patel, ... Nature protocols 11 (8), 1455-1476, 2016 | 501 | 2016 |
Mammalian heat shock response and mechanisms underlying its genome-wide transcriptional regulation DB Mahat, HH Salamanca, FM Duarte, CG Danko, JT Lis Molecular cell 62 (1), 63-78, 2016 | 424 | 2016 |
Transcriptional response to stress is pre-wired by promoter and enhancer architecture A Vihervaara, DB Mahat, MJ Guertin, T Chu, CG Danko, JT Lis, L Sistonen Nature communications 8 (1), 255, 2017 | 167 | 2017 |
Transcription factors GAF and HSF act at distinct regulatory steps to modulate stress-induced gene activation FM Duarte, NJ Fuda, DB Mahat, LJ Core, MJ Guertin, JT Lis Genes & development 30 (15), 1731-1746, 2016 | 146 | 2016 |
Transcriptional pause sites delineate stable nucleosome-associated premature polyadenylation suppressed by U1 snRNP AC Chiu, HI Suzuki, X Wu, DB Mahat, AJ Kriz, PA Sharp Molecular cell 69 (4), 648-663. e7, 2018 | 125 | 2018 |
CBP regulates recruitment and release of promoter-proximal RNA polymerase II A Boija*, DB Mahat*, A Zare, PH Holmqvist, P Philip, DJ Meyers, PA Cole, ... Molecular cell 68 (3), 491-503. e5, 2017 | 87 | 2017 |
A rapid, sensitive, scalable method for Precision Run-On sequencing (PRO-seq) J Judd, LA Wojenski, LM Wainman, ND Tippens, EJ Rice, A Dziubek, ... Biorxiv, 2020.05. 18.102277, 2020 | 47 | 2020 |
Stress-induced transcriptional memory accelerates promoter-proximal pause release and decelerates termination over mitotic divisions A Vihervaara, DB Mahat, SV Himanen, MAH Blom, JT Lis, L Sistonen Molecular cell 81 (8), 1715-1731. e6, 2021 | 46 | 2021 |
Single-cell nascent RNA sequencing unveils coordinated global transcription DB Mahat, ND Tippens, JD Martin-Rufino, SK Waterton, J Fu, SE Blatt, ... Nature 631 (8019), 216-223, 2024 | 26 | 2024 |
Use of conditioned media is critical for studies of regulation in response to rapid heat shock DB Mahat, JT Lis Cell Stress and Chaperones 22 (1), 155-162, 2017 | 25 | 2017 |
Coordinated expression of tristetraprolin post-transcriptionally attenuates mitogenic induction of the oncogenic Ser/Thr kinase Pim-1 DB Mahat, SE Brennan-Laun, EJ Fialcowitz-White, A Kishor, CR Ross, ... PLoS One 7 (3), e33194, 2012 | 18 | 2012 |
Transcription factor antagonism regulates heterogeneity in embryonic stem cell states S Hu, E Metcalf, DB Mahat, L Chan, N Sohal, M Chakraborty, M Hamilton, ... Molecular cell 82 (23), 4410-4427. e12, 2022 | 16 | 2022 |
Single-cell nascent RNA sequencing using click-chemistry unveils coordinated transcription DB Mahat, ND Tippens, JD Martin-Rufino, SK Waterton, J Fu, SE Blatt, ... bioRxiv, 2023 | 2 | 2023 |
Mutant p53 Exploits Enhancers to Elevate Immunosuppressive Chemokine Expression and Impair Immune Checkpoint Inhibitors in Pancreatic Cancer DB Mahat, H Kumra, SA Castro, E Metcalf, K Nguyen, R Morisue, WW Ho, ... bioRxiv, 2024 | | 2024 |
Abstract B087: Mutant-p53 amplifies Cxcl1 expression from distal enhancers blunting immune checkpoint inhibition efficacy in pancreatic cancer DB Mahat, H Kumra, E Metcalf, S Castro, K Nguyen1, A Singh, WW Ho, ... Cancer Research 84 (2_Supplement), B087-B087, 2024 | | 2024 |
Mutant-p53 amplifies Cxcl1 expression from distal enhancers blunting immune checkpoint inhibition efficacy in pancreatic cancer DB Mahat, H Kumra, E Metcalf, S Castro, K Nguyen, A Singh, WW Ho, ... CANCER RESEARCH 84 (2), 2024 | | 2024 |
1517 Mutant-p53 amplifies Cxcl1 expression from distal enhancers blunting immune checkpoint inhibition efficacy in pancreatic cancer DB Mahat, H Kumra, E Metcalf, S Castro, K Nguyen, WW Ho, I Chen, ... Journal for ImmunoTherapy of Cancer 11 (Suppl 2), 2023 | | 2023 |
Dissection of the Mechanisms Underlying Genome-Wide Transcriptional Regulation of Mammalian Stress Response DB Mahat Cornell University, 2017 | | 2017 |
Abstract IA05: Genome-wide views into the mechanisms of transcription regulation JT Lis, C Danko, F Duarte, DB Mahat Cancer Research 76 (2_Supplement), IA05-IA05, 2016 | | 2016 |
A Unified Model Describing The Architecture And Creation Of Promoters And Enhancers J Lis, L Core, A Martins, C Danko, A Siepel, G Booth, F Duarte, DB Mahat The FASEB Journal 29, 497.3, 2015 | | 2015 |