Reciprocal regulation between the circadian clock and hypoxia signaling at the genome level in mammals Y Wu, D Tang, N Liu, W Xiong, H Huang, Y Li, Z Ma, H Zhao, P Chen, X Qi, ... Cell metabolism 25 (1), 73-85, 2017 | 275 | 2017 |
Targeting BCAA catabolism to treat obesity-associated insulin resistance M Zhou, J Shao, CY Wu, L Shu, W Dong, Y Liu, M Chen, RM Wynn, ... Diabetes 68 (9), 1730-1746, 2019 | 274 | 2019 |
A general strategy for synthesis of cyclophane-braced peptide macrocycles via palladium-catalysed intramolecular sp3 C−H arylation X Zhang, G Lu, M Sun, M Mahankali, Y Ma, M Zhang, W Hua, Y Hu, ... Nature chemistry 10 (5), 540-548, 2018 | 209 | 2018 |
Chiral allene-containing phosphines in asymmetric catalysis F Cai, X Pu, X Qi, V Lynch, A Radha, JM Ready Journal of the American Chemical Society 133 (45), 18066-18069, 2011 | 167 | 2011 |
Discovery of a molecular glue promoting CDK12-DDB1 interaction to trigger cyclin K degradation L Lv, P Chen, L Cao, Y Li, Z Zeng, Y Cui, Q Wu, J Li, JH Wang, MQ Dong, ... Elife 9, e59994, 2020 | 158 | 2020 |
Allenes in Asymmetric Catalysis: Asymmetric Ring Opening of meso-Epoxides Catalyzed by Allene-Containing Phosphine Oxides X Pu, X Qi, JM Ready Journal of the American Chemical Society 131 (30), 10364-10365, 2009 | 158 | 2009 |
Shigella evades pyroptosis by arginine ADP-riboxanation of caspase-11 Z Li, W Liu, J Fu, S Cheng, Y Xu, Z Wang, X Liu, X Shi, Y Liu, X Qi, X Liu, ... Nature 599 (7884), 290-295, 2021 | 155 | 2021 |
Total synthesis of (±)-trigonoliimine C via oxidative rearrangement of an unsymmetrical bis-tryptamine X Qi, H Bao, UK Tambar Journal of the American Chemical Society 133 (26), 10050-10053, 2011 | 120 | 2011 |
Copper-Promoted Cyloaddition of Diazocarbonyl Compounds and Acetylides X Qi, JM Ready Angewandte Chemie (International ed. in English) 46 (18), 3242, 2007 | 117 | 2007 |
A hybridization-chain-reaction-based method for amplifying immunosignals R Lin, Q Feng, P Li, P Zhou, R Wang, Z Liu, Z Wang, X Qi, N Tang, F Shao, ... Nature methods 15 (4), 275-278, 2018 | 112 | 2018 |
Structure-guided development of specific pyruvate dehydrogenase kinase inhibitors targeting the ATP-binding pocket SC Tso, X Qi, WJ Gui, CY Wu, JL Chuang, I Wernstedt-Asterholm, ... Journal of Biological Chemistry 289 (7), 4432-4443, 2014 | 107 | 2014 |
Benzothiophene carboxylate derivatives as novel allosteric inhibitors of branched-chain α-ketoacid dehydrogenase kinase SC Tso, WJ Gui, CY Wu, JL Chuang, X Qi, KJ Skvorak, K Dorko, ... Journal of Biological Chemistry 289 (30), 20583-20593, 2014 | 103 | 2014 |
Estrogen-related hormones induce apoptosis by stabilizing schlafen-12 protein turnover D Li, J Chen, Y Ai, X Gu, L Li, D Che, Z Jiang, L Li, S Chen, H Huang, ... Molecular cell 75 (6), 1103-1116. e9, 2019 | 85 | 2019 |
Structure-based design and mechanisms of allosteric inhibitors for mitochondrial branched-chain α-ketoacid dehydrogenase kinase SC Tso, X Qi, WJ Gui, JL Chuang, LK Morlock, AL Wallace, K Ahmed, ... Proceedings of the National Academy of Sciences 110 (24), 9728-9733, 2013 | 80 | 2013 |
Diversification of a β-lactam pharmacophore via allylic C–H amination: accelerating effect of Lewis acid co-catalyst XB Qi, GT Rice, MS Lall, MS Plummer, MC White Tetrahedron 66 (26), 4816-4826, 2010 | 78 | 2010 |
Synthesis of Cylopentenones from Cylopropanes and Ynol Silanes X Qi, JM Ready Angewandte Chemie (International ed. in English) 47 (37), 7068, 2008 | 77 | 2008 |
Catalytic Enantioselective [2,3]-Rearrangements of Amine N-Oxides H Bao, X Qi, UK Tambar Journal of the American Chemical Society 133 (5), 1206-1208, 2011 | 70* | 2011 |
Response dynamics of midbrain dopamine neurons and serotonin neurons to heroin, nicotine, cocaine, and MDMA C Wei, X Han, D Weng, Q Feng, X Qi, J Li, M Luo Cell discovery 4 (1), 60, 2018 | 67 | 2018 |
Visible-light-induced nickel-catalyzed cross-coupling with alkylzirconocenes from unactivated alkenes Y Gao, C Yang, S Bai, X Liu, Q Wu, J Wang, C Jiang, X Qi Chem 6 (3), 675-688, 2020 | 65 | 2020 |
Targeting hepatic pyruvate dehydrogenase kinases restores insulin signaling and mitigates ChREBP-mediated lipogenesis in diet-induced obese mice CY Wu, SC Tso, JL Chuang, WJ Gui, M Lou, G Sharma, C Khemtong, X Qi, ... Molecular metabolism 12, 12-24, 2018 | 46 | 2018 |