Dysregulated cholesterol homeostasis results in resistance to ferroptosis increasing tumorigenicity and metastasis in cancer W Liu, B Chakraborty, R Safi, D Kazmin, C Chang, DP McDonnell Nature communications 12 (1), 5103, 2021 | 220 | 2021 |
Estrogen receptor signaling in the immune system B Chakraborty, J Byemerwa, T Krebs, F Lim, CY Chang, DP McDonnell Endocrine reviews 44 (1), 117-141, 2023 | 114 | 2023 |
Inhibition of estrogen signaling in myeloid cells increases tumor immunity in melanoma Journal of Clinical Investigation, 2021 | 77 | 2021 |
Kinase suppressor of ras 1 (KSR1) regulates PGC1α and estrogen-related receptor α to promote oncogenic Ras-dependent anchorage-independent growth KW Fisher, B Das, RL Kortum, OV Chaika, RE Lewis Molecular and cellular biology 31 (12), 2453-2461, 2011 | 56 | 2011 |
WDR5 supports colon cancer cells by promoting methylation of H3K4 and suppressing DNA damage BK Neilsen, B Chakraborty, JL McCall, DE Frodyma, RL Sleightholm, ... BMC cancer 18, 1-13, 2018 | 46 | 2018 |
AMPK promotes aberrant PGC1β expression to support human colon tumor cell survival KW Fisher, B Das, HS Kim, BK Clymer, D Gehring, DR Smith, ... Molecular and cellular biology 35 (22), 3866-3879, 2015 | 42 | 2015 |
KSR1 and EPHB4 regulate Myc and PGC1β to promote survival of human colon tumors JL McCall, D Gehring, BK Clymer, KW Fisher, B Das, DL Kelly, H Kim, ... Molecular and cellular biology 36 (17), 2246-2261, 2016 | 40 | 2016 |
A Functional Signature Ontology (FUSION) screen detects an AMPK inhibitor with selective toxicity toward human colon tumor cells B Das, BK Neilsen, KW Fisher, D Gehring, Y Hu, DJ Volle, HS Kim, ... Scientific reports 8 (1), 3770, 2018 | 21 | 2018 |
A gene expression high-throughput screen (GE-HTS) for coordinated detection of functionally similar effectors in cancer C Rao, DH Huisman, HM Vieira, DE Frodyma, BK Neilsen, B Chakraborty, ... Cancers 12 (11), 3143, 2020 | 13 | 2020 |
Targeting CaMKK2 inhibits actin cytoskeletal assembly to suppress cancer metastasis D Mukherjee, RA Previs, C Haines, M Al Abo, PK Juras, KC Strickland, ... Cancer research 83 (17), 2889-2907, 2023 | 9 | 2023 |
Dysregulated cholesterol homeostasis results in resistance to ferroptosis increasing tumorigenicity and metastasis in cancer. Nat Commun 12: 5103 W Liu, B Chakraborty, R Safi, D Kazmin, CY Chang, DP McDonnell | 7 | 2021 |
High-throughput identification of protein functional similarities using a gene-expression-based siRNA screen BK Neilsen, DL Kelly, B Chakraborty, HS Kim, MA White, RE Lewis, ... Scientific Data 7 (1), 27, 2020 | 6 | 2020 |
Estrogen signaling suppresses tumor-associated tissue eosinophilia to promote breast tumor growth S Artham, PK Juras, A Goyal, P Chakraborty, J Byemerwa, S Liu, ... Science Advances 10 (39), eadp2442, 2024 | 4 | 2024 |
Ca2+/Calmodulin Dependent Protein Kinase Kinase-2 (CaMKK2) promotes Protein Kinase G (PKG)-dependent actin cytoskeletal assembly to increase tumor … D Mukherjee, RA Previs, CN Haines, MA Abo, PK Juras, KC Strickland, ... bioRxiv, 2023.04. 17.536051, 2023 | 1 | 2023 |
Abstract A44: Pharmacologic targeting of estrogen receptor in melanoma to enhance antitumor immunity B Chakraborty, J Bymerwa, R Baldi, W Liu, CY Chang, D McDonnell Cancer Immunology Research 8 (3_Supplement), A44-A44, 2020 | 1 | 2020 |
COMPOSITIONS COMPRISING SMALL MOLECULE REGULATORS OF TUMOR IMMUNITY AND METHODS OF USING SAME D Mcdonnell, B Chakraborty, C Chang, J Byemerwa US Patent App. 18/697,976, 2024 | | 2024 |
8595 Brain Penetration Impedes SERD Efficacy in Breast Cancer Pre-clinical Models SE Wardell, B Chakraborty, S Artham, MA Newlin, M Kirkland, C Chang, ... Journal of the Endocrine Society 8 (Supplement_1), bvae163. 1793, 2024 | | 2024 |
Targeting estrogen receptor signaling in tumor associated myeloid cells to enhance anti-tumor immunity B Chakraborty, M Brown, P Chakraborty, A Goyal, CY Chang, ... Cancer Research 84 (6_Supplement), 6535-6535, 2024 | | 2024 |
Abstract B033: Targeting CaMKK2 inhibits actin cytoskeletal assembly to suppress cancer metastasis D Mukherjee, RA Previs, CN Haines, MA Abo, PK Juras, KC Strickland, ... Cancer Research 84 (3_Supplement_1), B033-B033, 2024 | | 2024 |
Estrogens increase cancer cell efferocytosis to establish an immunosuppressive tumor microenvironment B Chakraborty, P Chakraborty, MC Brown, D Crowder, A Goyal, R Safi, ... bioRxiv, 2024.12. 26.630419, 2024 | | 2024 |