| Trisomy 21 dysregulates T cell lineages toward an autoimmunity-prone state associated with interferon hyperactivity P Araya, KA Waugh, KD Sullivan, NG Núñez, E Roselli, KP Smith, ... Proceedings of the National Academy of Sciences 116 (48), 24231-24241, 2019 | 118 | 2019 |
| Mass cytometry reveals global immune remodeling with multi-lineage hypersensitivity to type I interferon in Down syndrome KA Waugh, P Araya, A Pandey, KR Jordan, KP Smith, RE Granrath, ... Cell reports 29 (7), 1893-1908. e4, 2019 | 111 | 2019 |
| Specialized interferon action in COVID-19 MD Galbraith, KT Kinning, KD Sullivan, P Araya, KP Smith, RE Granrath, ... Proceedings of the National Academy of Sciences 119 (11), e2116730119, 2022 | 87 | 2022 |
| Seroconversion stages COVID19 into distinct pathophysiological states MD Galbraith, KT Kinning, KD Sullivan, R Baxter, P Araya, KR Jordan, ... Elife 10, e65508, 2021 | 54 | 2021 |
| The COVIDome explorer researcher portal KD Sullivan, MD Galbraith, KT Kinning, KW Bartsch, NC Levinsky, ... Cell reports 36 (7), 2021 | 41 | 2021 |
| Photodynamic modulation of type 1 interferon pathway on melanoma cells promotes dendritic cell activation MJ Lamberti, FM Mentucci, E Roselli, P Araya, VA Rivarola, ... Frontiers in immunology 10, 2614, 2019 | 40 | 2019 |
| TLR3 Activation of Intratumoral CD103+ Dendritic Cells Modifies the Tumor Infiltrate Conferring Anti-tumor Immunity E Roselli, P Araya, NG Núñez, G Gatti, F Graziano, C Sedlik, P Benaroch, ... Frontiers in immunology 10, 503, 2019 | 35 | 2019 |
| Triplication of the interferon receptor locus contributes to hallmarks of Down syndrome in a mouse model KA Waugh, R Minter, J Baxter, C Chi, MD Galbraith, KD Tuttle, ... Nature genetics 55 (6), 1034-1047, 2023 | 34 | 2023 |
| JAK1 inhibition blocks lethal immune hypersensitivity in a mouse model of down syndrome KD Tuttle, KA Waugh, P Araya, R Minter, DJ Orlicky, M Ludwig, Z Andrysik, ... Cell reports 33 (7), 2020 | 27 | 2020 |
| Multidimensional definition of the interferonopathy of Down syndrome and its response to JAK inhibition MD Galbraith, AL Rachubinski, KP Smith, P Araya, KA Waugh, ... Science Advances 9 (26), eadg6218, 2023 | 26 | 2023 |
| High IRF8 expression correlates with CD8 T cell infiltration and is a predictive biomarker of therapy response in ER-negative breast cancer G Gatti, C Betts, D Rocha, M Nicola, V Grupe, C Ditada, NG Nuñez, ... Breast Cancer Research 23, 1-15, 2021 | 22 | 2021 |
| IGF1 deficiency integrates stunted growth and neurodegeneration in Down syndrome P Araya, KT Kinning, C Coughlan, KP Smith, RE Granrath, ... Cell reports 41 (13), 2022 | 19 | 2022 |
| In vivo visualizing the IFN-β response required for tumor growth control in a therapeutic model of polyadenylic-polyuridylic acid administration DA Nocera, E Roselli, P Araya, NG Nunez, S Lienenklaus, J Jablonska, ... The Journal of Immunology 196 (6), 2860-2869, 2016 | 15 | 2016 |
| JAK1 inhibition blocks lethal sterile immune responses: implications for COVID-19 therapy KD Tuttle, R Minter, KA Waugh, P Araya, M Ludwig, C Sempeck, K Smith, ... BioRxiv, 2020.04. 07.024455, 2020 | 12 | 2020 |
| Mass cytometry reveals global immune remodeling with multi-lineage hypersensitivity to type I interferon in Down syndrome. Cell Rep 29: 1893–1908. e4 KA Waugh, P Araya, A Pandey, KR Jordan, KP Smith, RE Granrath, ... | 10 | 2019 |
| Downregulation of adaptor protein MyD88 compromises the angiogenic potential of B16 murine melanoma LD Trucco, E Roselli, P Araya, NG Nuñez, HA Mena, JL Bocco, S Negrotto, ... PloS one 12 (6), e0179897, 2017 | 7 | 2017 |
| Plasma neurofilament light chain concentrations are elevated in youth‐onset type 2 diabetes and associated with neuropathy V Fridman, S Sillau, A Ritchie, J Bockhorst, C Coughlan, P Araya, ... Journal of the Peripheral Nervous System 28 (3), 460-470, 2023 | 6 | 2023 |
| Interferon receptor gene dosage determines diverse hallmarks of Down syndrome KA Waugh, R Minter, J Baxter, C Chi, KD Tuttle, NP Eduthan, ... BioRxiv, 2022.02. 03.478982, 2022 | 6 | 2022 |
| Variegated overexpression of chromosome 21 genes reveals molecular and immune subtypes of Down syndrome MG Donovan, NP Eduthan, KP Smith, EC Britton, HR Lyford, P Araya, ... Nature Communications 15 (1), 5473, 2024 | 5 | 2024 |
| JAK inhibition decreases the autoimmune burden in Down syndrome AL Rachubinski, E Wallace, E Gurnee, BA Enriquez-Estrada, KR Worek, ... eLife 13, RP99323, 2024 | 3 | 2024 |
Kelly D. SullivanAssociate Professor - Linda Crnic Institute for Down Syndrome - CU AnschutzPotvrđena adresa e-pošte na colorado.edu
