| Chemoresistance evolution in triple-negative breast cancer delineated by single-cell sequencing C Kim, R Gao, E Sei, R Brandt, J Hartman, T Hatschek, N Crosetto, ... Cell 173 (4), 879-893. e13, 2018 | 1004 | 2018 |
| Ubiquitin-binding domains in Y-family polymerases regulate translesion synthesis M Bienko, CM Green, N Crosetto, F Rudolf, G Zapart, B Coull, ... Science 310 (5755), 1821-1824, 2005 | 878 | 2005 |
| Nucleotide-resolution DNA double-strand break mapping by next-generation sequencing N Crosetto, A Mitra, MJ Silva, M Bienko, N Dojer, Q Wang, E Karaca, ... Nature methods 10 (4), 361-365, 2013 | 541 | 2013 |
| Spatially resolved transcriptomics and beyond N Crosetto, M Bienko, A Van Oudenaarden Nature Reviews Genetics 16 (1), 57-66, 2015 | 540 | 2015 |
| Engineered Cpf1 variants with altered PAM specificities L Gao, DBT Cox, WX Yan, JC Manteiga, MW Schneider, T Yamano, ... Nature biotechnology 35 (8), 789-792, 2017 | 494 | 2017 |
| Regulation of ubiquitin-binding proteins by monoubiquitination D Hoeller, N Crosetto, B Blagoev, C Raiborg, R Tikkanen, S Wagner, ... Nature cell biology 8 (2), 163-169, 2006 | 390 | 2006 |
| BLISS is a versatile and quantitative method for genome-wide profiling of DNA double-strand breaks WX Yan, R Mirzazadeh, S Garnerone, D Scott, MW Schneider, T Kallas, ... Nature communications 8 (1), 15058, 2017 | 385 | 2017 |
| Synthetic lethality between androgen receptor signalling and the PARP pathway in prostate cancer M Asim, F Tarish, HI Zecchini, K Sanjiv, E Gelali, CE Massie, A Baridi, ... Nature communications 8 (1), 374, 2017 | 302 | 2017 |
| Flt3-dependent transformation by inactivating c-Cbl mutations in AML B Sargin, C Choudhary, N Crosetto, MHH Schmidt, R Grundler, ... Blood, The Journal of the American Society of Hematology 110 (3), 1004-1012, 2007 | 266 | 2007 |
| Colibactin DNA-damage signature indicates mutational impact in colorectal cancer PJ Dziubańska-Kusibab, H Berger, F Battistini, BAM Bouwman, A Iftekhar, ... Nature medicine 26 (7), 1063-1069, 2020 | 234 | 2020 |
| Regulation of translesion synthesis DNA polymerase η by monoubiquitination M Bienko, CM Green, S Sabbioneda, N Crosetto, I Matic, RG Hibbert, ... Molecular cell 37 (3), 396-407, 2010 | 217 | 2010 |
| What determines the specificity and outcomes of ubiquitin signaling? F Ikeda, N Crosetto, I Dikic Cell 143 (5), 677-681, 2010 | 204 | 2010 |
| Combined inhibition of DDR1 and Notch signaling is a therapeutic strategy for KRAS-driven lung adenocarcinoma C Ambrogio, G Gomez-Lopez, M Falcone, A Vidal, E Nadal, N Crosetto, ... Nature medicine 22 (3), 270-277, 2016 | 200 | 2016 |
| Suppressors of T-cell receptor signaling Sts-1 and Sts-2 bind to Cbl and inhibit endocytosis of receptor tyrosine kinases K Kowanetz, N Crosetto, K Haglund, MHH Schmidt, CH Heldin, I Dikic Journal of biological chemistry 279 (31), 32786-32795, 2004 | 171 | 2004 |
| Single-cell 5hmC sequencing reveals chromosome-wide cell-to-cell variability and enables lineage reconstruction D Mooijman, SS Dey, JC Boisset, N Crosetto, A Van Oudenaarden Nature biotechnology 34 (8), 852-856, 2016 | 166 | 2016 |
| Spatial chromosome folding and active transcription drive DNA fragility and formation of oncogenic MLL translocations HJ Gothe, BAM Bouwman, EG Gusmao, R Piccinno, G Petrosino, ... Molecular cell 75 (2), 267-283. e12, 2019 | 156 | 2019 |
| Nanogrid single-nucleus RNA sequencing reveals phenotypic diversity in breast cancer R Gao, C Kim, E Sei, T Foukakis, N Crosetto, LK Chan, M Srinivasan, ... Nature communications 8 (1), 228, 2017 | 128 | 2017 |
| A damaged genome’s transcriptional landscape through multilayered expression profiling around in situ-mapped DNA double-strand breaks F Iannelli, A Galbiati, I Capozzo, Q Nguyen, B Magnuson, F Michelini, ... Nature communications 8 (1), 15656, 2017 | 119 | 2017 |
| Deubiquitination of EGFR by Cezanne-1 contributes to cancer progression F Pareja, DA Ferraro, C Rubin, H Cohen-Dvashi, F Zhang, S Aulmann, ... Oncogene 31 (43), 4599-4608, 2012 | 109 | 2012 |
| Release of paused RNA polymerase II at specific loci favors DNA double-strand-break formation and promotes cancer translocations GI Dellino, F Palluzzi, AM Chiariello, R Piccioni, S Bianco, L Furia, ... Nature genetics 51 (6), 1011-1023, 2019 | 106 | 2019 |