| Embryonic and adult-derived resident cardiac macrophages are maintained through distinct mechanisms at steady state and during inflammation S Epelman, KJ Lavine, AE Beaudin, DK Sojka, JA Carrero, B Calderon, ... Immunity 40 (1), 91-104, 2014 | 1552 | 2014 |
| Exploiting macrophage autophagy-lysosomal biogenesis as a therapy for atherosclerosis I Sergin, TD Evans, X Zhang, S Bhattacharya, CJ Stokes, E Song, S Ali, ... Nature communications 8 (1), 15750, 2017 | 316 | 2017 |
| Induction of lysosomal biogenesis in atherosclerotic macrophages can rescue lipid-induced lysosomal dysfunction and downstream sequelae R Emanuel, I Sergin, S Bhattacharya, JN Turner, S Epelman, C Settembre, ... Arteriosclerosis, thrombosis, and vascular biology 34 (9), 1942-1952, 2014 | 239 | 2014 |
| TFEB and trehalose drive the macrophage autophagy-lysosome system to protect against atherosclerosis TD Evans, SJ Jeong, X Zhang, I Sergin, B Razani Autophagy 14 (4), 724-726, 2018 | 164 | 2018 |
| High-protein diets increase cardiovascular risk by activating macrophage mTOR to suppress mitophagy X Zhang, I Sergin, TD Evans, SJ Jeong, A Rodriguez-Velez, D Kapoor, ... Nature metabolism 2 (1), 110-125, 2020 | 126 | 2020 |
| Self-eating in the plaque: what macrophage autophagy reveals about atherosclerosis I Sergin, B Razani Trends in Endocrinology & Metabolism 25 (5), 225-234, 2014 | 125 | 2014 |
| Inclusion bodies enriched for p62 and polyubiquitinated proteins in macrophages protect against atherosclerosis I Sergin, S Bhattacharya, R Emanuel, E Esen, CJ Stokes, TD Evans, B Arif, ... Science signaling 9 (409), ra2-ra2, 2016 | 115 | 2016 |
| Location-dependent signaling of the group 1 metabotropic glutamate receptor mGlu5 YJI Jong, I Sergin, CA Purgert, KL O’Malley Molecular pharmacology 86 (6), 774-785, 2014 | 71 | 2014 |
| Target acquired: selective autophagy in cardiometabolic disease TD Evans, I Sergin, X Zhang, B Razani Science signaling 10 (468), eaag2298, 2017 | 69 | 2017 |
| N-3 PUFAs induce inflammatory tolerance by formation of KEAP1-containing SQSTM1/p62-bodies and activation of NFE2L2 J Mildenberger, I Johansson, I Sergin, E Kjøbli, JK Damås, B Razani, ... Autophagy 13 (10), 1664-1678, 2017 | 62 | 2017 |
| A clinically applicable gene-expression classifier reveals intrinsic and extrinsic contributions to consensus molecular subtypes in primary and metastatic colon cancer R Piskol, L Huw, I Sergin, Z Modrusan, D Kim, N Kljavin, R Tam, R Patel, ... Clinical Cancer Research 25 (14), 4431-4442, 2019 | 55 | 2019 |
| Ursolic acid enhances macrophage autophagy and attenuates atherogenesis S Leng, S Iwanowycz, F Saaoud, J Wang, Y Wang, I Sergin, B Razani, ... Journal of lipid research 57 (6), 1006-1016, 2016 | 52 | 2016 |
| Sequences within the C terminus of the metabotropic glutamate receptor 5 (mGluR5) are responsible for inner nuclear membrane localization I Sergin, YJI Jong, SK Harmon, V Kumar, KL O'Malley Journal of Biological Chemistry 292 (9), 3637-3655, 2017 | 45 | 2017 |
| Degradation and beyond: the macrophage lysosome as a nexus for nutrient sensing and processing in atherosclerosis I Sergin, TD Evans, B Razani Current opinion in lipidology 26 (5), 394-404, 2015 | 41 | 2015 |
| Anti-angiogenic nanotherapy inhibits airway remodeling and hyper-responsiveness of dust mite triggered asthma in the Brown Norway rat GM Lanza, J Jenkins, AH Schmieder, A Moldobaeva, G Cui, H Zhang, ... Theranostics 7 (2), 377, 2017 | 33 | 2017 |
| Identification of a leucine-mediated threshold effect governing macrophage mTOR signalling and cardiovascular risk X Zhang, D Kapoor, SJ Jeong, A Fappi, J Stitham, V Shabrish, I Sergin, ... Nature metabolism 6 (2), 359-377, 2024 | 25 | 2024 |
| MAP4K4 negatively regulates CD8 T cell–mediated antitumor and antiviral immunity E Esen, I Sergin, R Jesudason, P Himmels, JD Webster, H Zhang, M Xu, ... Science immunology 5 (45), eaay2245, 2020 | 23 | 2020 |
| Loss of macrophage mTORC2 drives atherosclerosis via FoxO1 and IL-1β signaling X Zhang, TD Evans, S Chen, I Sergin, J Stitham, SJ Jeong, ... Circulation research 133 (3), 200-219, 2023 | 15 | 2023 |
| Modulating oxysterol sensing to control macrophage apoptosis and atherosclerosis TD Evans, I Sergin, X Zhang, B Razani Circulation research 119 (12), 1258-1261, 2016 | 11 | 2016 |
| Hypoxia in plaque macrophages: a new danger signal for interleukin-1β activation? I Sergin, TD Evans, S Bhattacharya, B Razani Circulation research 115 (10), 817-820, 2014 | 11 | 2014 |
