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Rajat Rohatgi
Rajat Rohatgi
Professor of Biochemistry and Medicine, Stanford University
Potvrđena adresa e-pošte na stanford.edu - Početna stranica
Naslov
Citirano
Citirano
Godina
The interaction between N-WASP and the Arp2/3 complex links Cdc42-dependent signals to actin assembly
R Rohatgi, L Ma, H Miki, M Lopez, T Kirchhausen, T Takenawa, ...
Cell 97 (2), 221-231, 1999
17471999
Patched1 regulates hedgehog signaling at the primary cilium
R Rohatgi, L Milenkovic, MP Scott
Science 317 (5836), 372-376, 2007
16792007
Mechanism of regulation of WAVE1-induced actin nucleation by Rac1 and Nck
S Eden, R Rohatgi, AV Podtelejnikov, M Mann, MW Kirschner
Nature 418 (6899), 790-793, 2002
11042002
Mechanism of N-WASP activation by CDC42 and phosphatidylinositol 4, 5-bisphosphate
R Rohatgi, HH Ho, MW Kirschner
The Journal of cell biology 150 (6), 1299-1310, 2000
8252000
The output of Hedgehog signaling is controlled by the dynamic association between Suppressor of Fused and the Gli proteins
EW Humke, KV Dorn, L Milenkovic, MP Scott, R Rohatgi
Genes & development 24 (7), 670-682, 2010
5332010
Toca-1 mediates Cdc42-dependent actin nucleation by activating the N-WASP-WIP complex
HYH Ho, R Rohatgi, AM Lebensohn, L Ma, J Li, SP Gygi, MW Kirschner
Cell 118 (2), 203-216, 2004
5282004
Nck and phosphatidylinositol 4, 5-bisphosphate synergistically activate actin polymerization through the N-WASP-Arp2/3 pathway
R Rohatgi, P Nollau, HYH Ho, MW Kirschner, BJ Mayer
Journal of Biological Chemistry 276 (28), 26448-26452, 2001
5202001
A single N‐terminal phosphomimic disrupts TDP‐43 polymerization, phase separation, and RNA splicing
A Wang, AE Conicella, HB Schmidt, EW Martin, SN Rhoads, AN Reeb, ...
The EMBO journal 37 (5), e97452, 2018
4072018
Structural basis of Smoothened regulation by its extracellular domains
EFX Byrne, R Sircar, PS Miller, G Hedger, G Luchetti, S Nachtergaele, ...
Nature 535 (7613), 517-522, 2016
3792016
WIP regulates N-WASP-mediated actin polymerization and filopodium formation
N Martinez-Quiles, R Rohatgi, IM Antón, M Medina, SP Saville, H Miki, ...
Nature cell biology 3 (5), 484-491, 2001
3572001
Hedgehog signal transduction by Smoothened: pharmacologic evidence for a 2-step activation process
R Rohatgi, L Milenkovic, RB Corcoran, MP Scott
Proceedings of the National Academy of Sciences 106 (9), 3196-3201, 2009
3542009
Dynamic remodeling of membrane composition drives cell cycle through primary cilia excision
SC Phua, S Chiba, M Suzuki, E Su, EC Roberson, GV Pusapati, M Setou, ...
Cell 168 (1), 264-279. e15, 2017
3432017
Oxysterols are allosteric activators of the oncoprotein Smoothened
S Nachtergaele, LK Mydock, K Krishnan, J Rammohan, PH Schlesinger, ...
Nature chemical biology 8 (2), 211-220, 2012
3312012
TDP-43 α-helical structure tunes liquid–liquid phase separation and function
AE Conicella, GL Dignon, GH Zerze, HB Schmidt, AM D’Ordine, YC Kim, ...
Proceedings of the National Academy of Sciences 117 (11), 5883-5894, 2020
3272020
Lateral transport of Smoothened from the plasma membrane to the membrane of the cilium
L Milenkovic, MP Scott, R Rohatgi
Journal of Cell Biology 187 (3), 365-374, 2009
3202009
Cancer risk after use of recombinant bone morphogenetic protein-2 for spinal arthrodesis
EJ Carragee, G Chu, R Rohatgi, EL Hurwitz, BK Weiner, ST Yoon, ...
JBJS 95 (17), 1537-1545, 2013
2952013
The Arp2/3 complex mediates actin polymerization induced by the small GTP-binding protein Cdc42
LE Ma, R Rohatgi, MW Kirschner
Proceedings of the National Academy of Sciences 95 (26), 15362-15367, 1998
2851998
Gli protein activity is controlled by multisite phosphorylation in vertebrate Hedgehog signaling
P Niewiadomski, JH Kong, R Ahrends, Y Ma, EW Humke, S Khan, ...
Cell reports 6 (1), 168-181, 2014
2792014
Patching the gaps in Hedgehog signalling
R Rohatgi, MP Scott
Nature cell biology 9 (9), 1005-1009, 2007
2572007
Cholesterol activates the G-protein coupled receptor Smoothened to promote Hedgehog signaling
G Luchetti, R Sircar, JH Kong, S Nachtergaele, A Sagner, EFX Byrne, ...
Elife 5, e20304, 2016
2512016
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