GABA interneurons are the cellular trigger for ketamine’s rapid antidepressant actions DM Gerhard, S Pothula, RJ Liu, M Wu, XY Li, MJ Girgenti, SR Taylor, ... The Journal of clinical investigation 130 (3), 1336-1349, 2020 | 288 | 2020 |
Optogenetic stimulation of medial prefrontal cortex Drd1 neurons produces rapid and long-lasting antidepressant effects BD Hare, R Shinohara, RJ Liu, S Pothula, RJ DiLeone, RS Duman Nature communications 10 (1), 223, 2019 | 209 | 2019 |
Ketamine disinhibits dendrites and enhances calcium signals in prefrontal dendritic spines F Ali, DM Gerhard, K Sweasy, S Pothula, C Pittenger, RS Duman, ... Nature communications 11 (1), 72, 2020 | 190 | 2020 |
Antidepressant activity of methanolic extract of Passiflora foetida leaves in mice P Santosh, R Venugopl, AS Nilakash, S Kunjbihari, L Mangala Int J Pharm Pharm Sci 3 (1), 112-5, 2011 | 123 | 2011 |
Sestrin modulator NV-5138 produces rapid antidepressant effects via direct mTORC1 activation DRS Kato T, Pothula S, Liu RJ, Duman CH, Terwilliger R, Vlasuk GP, Saiah E ... Journal of Clinical investigation 130 (pii: 126859), 2019 | 78* | 2019 |
Cell-type specific modulation of NMDA receptors triggers antidepressant actions S Pothula, T Kato, RJ Liu, M Wu, D Gerhard, R Shinohara, AN Sliby, ... Molecular psychiatry 26 (9), 5097-5111, 2021 | 71 | 2021 |
Molecular mechanisms driving homeostatic plasticity of neurotransmitter release V Lazarevic, S Pothula, M Andres-Alonso, A Fejtova Frontiers in cellular neuroscience 7, 244, 2013 | 64 | 2013 |
Aberrant neuronal activity-induced signaling and gene expression in a mouse model of RASopathy F Altmüller, S Pothula, A Annamneedi, S Nakhaei-Rad, ... PLoS genetics 13 (3), e1006684, 2017 | 34 | 2017 |
Ketamine increases vmPFC activity: effects of (R)-and (S)-stereoisomers and (2R, 6R)-hydroxynorketamine metabolite BD Hare, S Pothula, RJ DiLeone, RS Duman Neuropharmacology 166, 107947, 2020 | 28 | 2020 |
Positive modulation of NMDA receptors by AGN-241751 exerts rapid antidepressant-like effects via excitatory neurons S Pothula, RJ Liu, M Wu, AN Sliby, MR Picciotto, P Banerjee, RS Duman Neuropsychopharmacology 46 (4), 799-808, 2021 | 27 | 2021 |
Inhibitory regulation of calcium transients in prefrontal dendritic spines is compromised by a nonsense Shank3 mutation RSDACK Farhan Ali, Ling-Xiao Shao, Danielle M. Gerhard, Katherine Sweasy ... Molecular Psychiatry, 2020 | 24* | 2020 |
Stress and its impact on the transcriptome MJ Girgenti, S Pothula, SS Newton Biological psychiatry 90 (2), 102-108, 2021 | 21 | 2021 |
Positive modulation of N-methyl-D-aspartate receptors in the mPFC reduces the spontaneous recovery of fear B Lee, S Pothula, M Wu, H Kang, MJ Girgenti, MR Picciotto, RJ DiLeone, ... Molecular Psychiatry 27 (5), 2580-2589, 2022 | 15 | 2022 |
Anxiolytic effect of ethanolic extract of Oxalis corniculata L. in mice TS Sampath, P Santosh, AP Mangala, KS Pavan, A Lingesh Int J Pharm Bio Sci 2, 281-90, 2011 | 13 | 2011 |
NMDAR modulators as rapid antidepressants: Converging and distinct signaling mechanisms RSD Boyoung Lee, Santosh Pothula Integrative Clinical Medicine, 2020 | 4 | 2020 |
Examining sex differences in responses to footshock stress and the role of the metabotropic glutamate receptor 5: an [18F]FPEB and positron emission tomography … RH Asch, S Pothula, T Toyonaga, K Fowles, SM Groman, R Garcia-Milian, ... Neuropsychopharmacology 48 (3), 489-497, 2023 | 3 | 2023 |
GluN2B‐containing NMDA Receptors on Sst‐interneurons act as Initial Cellular Trigger for Antidepressant Actions of Ketamine S Pothula, RJ Liu, M Wu, AN Sliby, R DiLeone, R Duman The FASEB Journal 35, 2021 | 1 | 2021 |
GluN2B-NMDARs on Gabaergic Interneurons Mediate the Antidepressant-like, but not Psychotomimetic, Effects of Ketamine in Mice S Pothula, AN Sliby, M Wu, RJ Liu, R DiLeone, R Duman NEUROPSYCHOPHARMACOLOGY 47 (SUPPL 1), 265-265, 2022 | | 2022 |
Risk and resilience in a rodent model of posttraumatic stress disorder: an in vivo [F-18] FPEB and positron emission tomography imaging study examining the role of metabotropic … RH Asch, S Pothula, T Toyonaga, K Fowles, SM Groman, R Garcia-Milian, ... JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM 41 (1_ SUPPL), 172-173, 2021 | | 2021 |
Ketamine disinhibits dendrites and enhances calcium signals in prefrontal dendritic spines (vol 11, 72, 2020) F Ali, DM Gerhard, K Sweasy, S Pothula, C Pittenger, RS Duman, ... NATURE COMMUNICATIONS 12 (1), 2021 | | 2021 |