Prati
Nicolas R. Barthélemy
Nicolas R. Barthélemy
Assistant Professor of Neurology, Washington University in St Louis School of Medicine
Potvrđena adresa e-pošte na neuro.wustl.edu - Početna stranica
Naslov
Citirano
Citirano
Godina
Tau kinetics in neurons and the human central nervous system
C Sato, NR Barthélemy, KG Mawuenyega, BW Patterson, BA Gordon, ...
Neuron 97 (6), 1284-1298. e7, 2018
5972018
A soluble phosphorylated tau signature links tau, amyloid and the evolution of stages of dominantly inherited Alzheimer’s disease
NR Barthélemy, Y Li, N Joseph-Mathurin, BA Gordon, J Hassenstab, ...
Nature medicine 26 (3), 398-407, 2020
5282020
Blood plasma phosphorylated-tau isoforms track CNS change in Alzheimer’s disease
NR Barthélemy, K Horie, C Sato, RJ Bateman
Journal of Experimental Medicine 217 (11), e20200861, 2020
3742020
Head-to-head comparison of 10 plasma phospho-tau assays in prodromal Alzheimer’s disease
S Janelidze, D Bali, NJ Ashton, NR Barthélemy, J Vanbrabant, E Stoops, ...
Brain 146 (4), 1592-1601, 2023
2712023
Neurofilaments: neurobiological foundations for biomarker applications
AR Gafson, NR Barthélemy, P Bomont, RO Carare, HD Durham, JP Julien, ...
Brain 143 (7), 1975-1998, 2020
2602020
Cerebrospinal fluid phospho-tau T217 outperforms T181 as a biomarker for the differential diagnosis of Alzheimer’s disease and PET amyloid-positive patient identification
NR Barthélemy, RJ Bateman, C Hirtz, P Marin, F Becher, C Sato, ...
Alzheimer's research & therapy 12, 1-11, 2020
2172020
Highly accurate blood test for Alzheimer’s disease is similar or superior to clinical cerebrospinal fluid tests
NR Barthélemy, G Salvadó, SE Schindler, Y He, S Janelidze, LE Collij, ...
Nature medicine 30 (4), 1085-1095, 2024
1462024
Tau phosphorylation rates measured by mass spectrometry differ in the intracellular brain versus extracellular cerebrospinal fluid compartments and are differentially affected …
NR Barthélemy, N Mallipeddi, P Moiseyev, C Sato, RJ Bateman
Frontiers in Aging Neuroscience 11, 121, 2019
1412019
Differential Mass Spectrometry Profiles of Tau Protein in the Cerebrospinal Fluid of Patients with Alzheimer’s Disease, Progressive Supranuclear Palsy, and Dementia with Lewy …
NR Barthélemy, A Gabelle, C Hirtz, F Fenaille, N Sergeant, ...
Journal of Alzheimer's Disease, 1-11, 2016
1412016
Soluble TREM2 in CSF and its association with other biomarkers and cognition in autosomal-dominant Alzheimer's disease: a longitudinal observational study
E Morenas-Rodríguez, Y Li, B Nuscher, N Franzmeier, C Xiong, ...
The Lancet Neurology 21 (4), 329-341, 2022
1272022
CSF tau microtubule binding region identifies tau tangle and clinical stages of Alzheimer’s disease
K Horie, NR Barthélemy, C Sato, RJ Bateman
Brain 144 (2), 515-527, 2021
1242021
Tau protein quantification in human cerebrospinal fluid by targeted mass spectrometry at high sequence coverage provides insights into its primary structure heterogeneity
NR Barthélemy, F Fenaille, C Hirtz, N Sergeant, S Schraen-Maschke, ...
Journal of Proteome Research, 2016
1222016
Sleep deprivation affects tau phosphorylation in human cerebrospinal fluid
NR Barthélemy, H Liu, W Lu, PT Kotzbauer, RJ Bateman, BP Lucey
Annals of neurology 87 (5), 700-709, 2020
1072020
CSF MTBR-tau243 is a specific biomarker of tau tangle pathology in Alzheimer’s disease
K Horie, G Salvadó, NR Barthélemy, S Janelidze, Y Li, Y He, B Saef, ...
Nature medicine 29 (8), 1954-1963, 2023
1042023
Cerebrospinal fluid proteomics define the natural history of autosomal dominant Alzheimer’s disease
ECB Johnson, S Bian, RU Haque, EK Carter, CM Watson, BA Gordon, ...
Nature medicine 29 (8), 1979-1988, 2023
792023
CSF tau phosphorylation occupancies at T217 and T205 represent improved biomarkers of amyloid and tau pathology in Alzheimer’s disease
NR Barthélemy, B Saef, Y Li, BA Gordon, Y He, K Horie, E Stomrud, ...
Nature Aging 3 (4), 391-401, 2023
732023
Mitigating the associations of kidney dysfunction with blood biomarkers of Alzheimer disease by using phosphorylated tau to total tau ratios
S Janelidze, NR Barthélemy, Y He, RJ Bateman, O Hansson
JAMA neurology 80 (5), 516-522, 2023
672023
CSF tau microtubule-binding region identifies pathological changes in primary tauopathies
K Horie, NR Barthélemy, S Spina, L VandeVrede, Y He, RW Paterson, ...
Nature medicine 28 (12), 2547-2554, 2022
612022
SILK studies—capturing the turnover of proteins linked to neurodegenerative diseases
RW Paterson, A Gabelle, BP Lucey, NR Barthélemy, CA Leckey, C Hirtz, ...
Nature Reviews Neurology 15 (7), 419-427, 2019
542019
Recapitulation of endogenous 4R tau expression and formation of insoluble tau in directly reprogrammed human neurons
LS Capano, C Sato, E Ficulle, A Yu, K Horie, JS Kwon, KF Burbach, ...
Cell Stem Cell 29 (6), 918-932. e8, 2022
502022
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