Prati
Jake A. Melby
Naslov
Citirano
Citirano
Godina
Novel strategies to address the challenges in top-down proteomics
JA Melby, DS Roberts, EJ Larson, KA Brown, EF Bayne, S Jin, Y Ge
Journal of the American Society for Mass Spectrometry 32 (6), 1278-1294, 2021
1632021
Top-down proteomics: challenges, innovations, and applications in basic and clinical research
KA Brown, JA Melby, DS Roberts, Y Ge
Expert review of proteomics 17 (10), 719-733, 2020
1272020
MASH explorer: a universal software environment for top-down proteomics
Z Wu, DS Roberts, JA Melby, K Wenger, M Wetzel, Y Gu, SG Ramanathan, ...
Journal of proteome research 19 (9), 3867-3876, 2020
812020
Structural O-glycoform heterogeneity of the SARS-CoV-2 spike protein receptor-binding domain revealed by top-down mass spectrometry
DS Roberts, M Mann, JA Melby, EJ Larson, Y Zhu, AR Brasier, S Jin, Y Ge
Journal of the American Chemical Society 143 (31), 12014-12024, 2021
692021
Ultrafast and reproducible proteomics from small amounts of heart tissue enabled by Azo and timsTOF pro
TJ Aballo, DS Roberts, JA Melby, KM Buck, KA Brown, Y Ge
Journal of Proteome Research 20 (8), 4203-4211, 2021
572021
High-throughput multi-attribute analysis of antibody-drug conjugates enabled by trapped ion mobility spectrometry and top-down mass spectrometry
EJ Larson, DS Roberts, JA Melby, KM Buck, Y Zhu, S Zhou, L Han, ...
Analytical chemistry 93 (29), 10013-10021, 2021
412021
High sensitivity top–down proteomics captures single muscle cell heterogeneity in large proteoforms
JA Melby, KA Brown, ZR Gregorich, DS Roberts, EA Chapman, LE Ehlers, ...
Proceedings of the National Academy of Sciences 120 (19), e2222081120, 2023
362023
Functionally integrated top-down proteomics for standardized assessment of human induced pluripotent stem cell-derived engineered cardiac tissues
JA Melby, WJ de Lange, J Zhang, DS Roberts, SD Mitchell, T Tucholski, ...
Journal of proteome research 20 (2), 1424-1433, 2021
232021
Defining the sarcomeric proteoform landscape in ischemic cardiomyopathy by top-down proteomics
EA Chapman, TJ Aballo, JA Melby, T Zhou, SJ Price, KJ Rossler, I Lei, ...
Journal of proteome research 22 (3), 931-941, 2023
212023
MASH Native: a unified solution for native top-down proteomics data processing
EJ Larson, MR Pergande, ME Moss, KJ Rossler, RK Wenger, B Krichel, ...
Bioinformatics 39 (6), btad359, 2023
182023
Top-down proteomics reveals myofilament proteoform heterogeneity among various rat skeletal muscle tissues
JA Melby, Y Jin, Z Lin, T Tucholski, Z Wu, ZR Gregorich, GM Diffee, Y Ge
Journal of proteome research 19 (1), 446-454, 2019
162019
Structure and dynamics of endogenous cardiac troponin complex in human heart tissue captured by native nanoproteomics
EA Chapman, DS Roberts, TN Tiambeng, J Andrews, MD Wang, ...
Nature Communications 14 (1), 8400, 2023
62023
Comprehensive characterization of endogenous phospholamban proteoforms enabled by photocleavable surfactant and top-down proteomics
HT Rogers, DS Roberts, EJ Larson, JA Melby, KJ Rossler, AV Carr, ...
Analytical Chemistry 95 (35), 13091-13100, 2023
62023
Size exclusion chromatography strategies and MASH explorer for large proteoform characterization
TN Tiambeng, Z Wu, JA Melby, Y Ge
Proteoform Identification: Methods and Protocols, 15-30, 2022
62022
Rbm20 ablation is associated with changes in the expression of titin-interacting and metabolic proteins
EJ Larson, ZR Gregorich, Y Zhang, BH Li, TJ Aballo, JA Melby, Y Ge, ...
Molecular omics 18 (7), 627-634, 2022
52022
Small-Scale Serial Size Exclusion Chromatography (s3SEC) for High Sensitivity Top-Down Proteomics of Large Proteoforms
HT Rogers, JA Melby, LE Ehlers, MS Fischer, EJ Larson, Z Gao, ...
Analytical Chemistry 96 (7), 2748-2753, 2024
42024
Lactate-and immunomagnetic-purified hiPSC–derived cardiomyocytes generate comparable engineered cardiac tissue constructs
KJ Rossler, WJ De Lange, MW Mann, TJ Aballo, JA Melby, J Zhang, ...
JCI insight 9 (1), 2024
22024
Quantum Cascade Laser Infrared Spectroscopy for Glycan Analysis of Glycoprotein Solutions
SM Kim, YR Chang, J Melby, YJ Kim, D Davis, YJ Lee
Analytical Chemistry 96 (32), 13120-13130, 2024
12024
Structure and dynamics of endogenous protein complexes in human heart tissue captured by native nanoproteomics
EA Chapman, DS Roberts, TN Tiambeng, J Andrews, MD Wang, ...
Research Square, 2023
12023
Novel Strategies to Address the Challenge of Sensitivity in Top-down Proteomics
JA Melby
The University of Wisconsin-Madison, 2023
2023
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