Prati
Hyuck Jin Lee
Hyuck Jin Lee
Potvrđena adresa e-pošte na kongju.ac.kr
Naslov
Citirano
Citirano
Godina
Towards an understanding of amyloid-β oligomers: characterization, toxicity mechanisms, and inhibitors
SJC Lee, E Nam, HJ Lee, MG Savelieff, MH Lim
Chemical Society Reviews 46 (2), 310-323, 2017
5542017
Development of multifunctional molecules as potential therapeutic candidates for Alzheimer’s disease, Parkinson’s disease, and amyotrophic lateral sclerosis in the last decade
MG Savelieff, G Nam, J Kang, HJ Lee, M Lee, MH Lim
Chemical reviews 119 (2), 1221-1322, 2018
5052018
Rational design of a structural framework with potential use to develop chemical reagents that target and modulate multiple facets of Alzheimer’s disease
S Lee, X Zheng, J Krishnamoorthy, MG Savelieff, HM Park, JR Brender, ...
Journal of the American Chemical Society 136 (1), 299-310, 2014
2092014
Cholesterol and metal ions in Alzheimer's disease
HJ Lee, KJ Korshavn, A Kochi, JS Derrick, MH Lim
Chemical Society Reviews 43 (19), 6672-6682, 2014
962014
A rationally designed small molecule for identifying an in vivo link between metal–amyloid-β complexes and the pathogenesis of Alzheimer's disease
MW Beck, SB Oh, RA Kerr, HJ Lee, SH Kim, S Kim, M Jang, BT Ruotolo, ...
Chemical Science 6 (3), 1879-1886, 2015
772015
Molecular insights into human serum albumin as a receptor of amyloid-β in the extracellular region
TS Choi, HJ Lee, JY Han, MH Lim, HI Kim
Journal of the American Chemical Society 139 (43), 15437-15445, 2017
742017
A redox-active, compact molecule for cross-linking amyloidogenic peptides into nontoxic, off-pathway aggregates: in vitro and in vivo efficacy and molecular mechanisms
JS Derrick, RA Kerr, Y Nam, SB Oh, HJ Lee, KG Earnest, N Suh, KL Peck, ...
Journal of the American Chemical Society 137 (46), 14785-14797, 2015
702015
A small molecule that displays marked reactivity toward copper–versus zinc–amyloid-β implicated in Alzheimer's disease
MG Savelieff, Y Liu, RRP Senthamarai, KJ Korshavn, HJ Lee, ...
Chemical Communications 50 (40), 5301-5303, 2014
602014
Redox-active metal ions and amyloid-degrading enzymes in Alzheimer’s disease
N Kim, HJ Lee
International Journal of Molecular Sciences 22 (14), 7697, 2021
492021
Structure and assembly mechanisms of toxic human islet amyloid polypeptide oligomers associated with copper
SJC Lee, TS Choi, JW Lee, HJ Lee, DG Mun, S Akashi, SW Lee, MH Lim, ...
Chemical Science 7 (8), 5398-5406, 2016
462016
An iridium (III) complex as a photoactivatable tool for oxidation of amyloidogenic peptides with subsequent modulation of peptide aggregation
J Kang, SJC Lee, JS Nam, HJ Lee, MG Kang, KJ Korshavn, HT Kim, ...
Chemistry–A European Journal 23 (7), 1645-1653, 2017
452017
Inhibitory activity of curcumin derivatives towards metal-free and metal-induced amyloid-β aggregation
A Kochi, H Jin Lee, S M Vithanarachchi, V Padmini, M J Allen, M Hee Lim
Current Alzheimer Research 12 (5), 415-423, 2015
432015
Synthetic flavonoids, aminoisoflavones: interaction and reactivity with metal-free and metal-associated amyloid-β species
AS DeToma, J Krishnamoorthy, Y Nam, HJ Lee, JR Brender, A Kochi, ...
Chemical science (Royal Society of Chemistry: 2010) 5 (12), 4851, 2014
402014
Multiple reactivities of flavonoids towards pathological elements in Alzheimer's disease: structure–activity relationship
G Nam, M Hong, J Lee, HJ Lee, Y Ji, J Kang, MH Baik, MH Lim
Chemical Science 11 (37), 10243-10254, 2020
342020
Minimalistic principles for designing small molecules with multiple reactivities against pathological factors in dementia
M Kim, J Kang, M Lee, J Han, G Nam, E Tak, MS Kim, HJ Lee, E Nam, ...
Journal of the American Chemical Society 142 (18), 8183-8193, 2020
322020
Chemical strategies to modify amyloidogenic peptides using iridium (iii) complexes: Coordination and photo-induced oxidation
J Kang, JS Nam, HJ Lee, G Nam, HW Rhee, TH Kwon, MH Lim
Chemical science 10 (28), 6855-6862, 2019
322019
Effects of hydroxyl group variations on a flavonoid backbone toward modulation of metal-free and metal-induced amyloid-β aggregation
HJ Lee, RA Kerr, KJ Korshavn, J Lee, J Kang, A Ramamoorthy, ...
Inorganic Chemistry Frontiers 3 (3), 381-392, 2016
322016
Structural and Mechanistic Insights into Development of Chemical Tools to Control Individual and Inter‐Related Pathological Features in Alzheimer's Disease
HJ Lee, KJ Korshavn, Y Nam, J Kang, TJ Paul, RA Kerr, IS Youn, M Ozbil, ...
Chemistry–A European Journal 23 (11), 2706-2715, 2017
312017
Mechanistic approaches for chemically modifying the coordination sphere of copper–amyloid-β complexes
J Han, HJ Lee, KY Kim, G Nam, J Chae, MH Lim
Proceedings of the National Academy of Sciences 117 (10), 5160-5167, 2020
302020
Tuning structures and properties for developing novel chemical tools toward distinct pathogenic elements in Alzheimer’s disease
J Han, HJ Lee, KY Kim, SJC Lee, JM Suh, J Cho, J Chae, MH Lim
ACS Chemical Neuroscience 9 (4), 800-808, 2017
302017
Sustav trenutno ne može provesti ovu radnju. Pokušajte ponovo kasnije.
Članci 1–20