Design, synthesis and biological evaluation of a new series of thiazolyl-pyrazolines as dual EGFR and HER2 inhibitors B Sever, MD Altıntop, MO Radwan, A Özdemir, M Otsuka, M Fujita, ... European journal of medicinal chemistry 182, 111648, 2019 | 96 | 2019 |
Thiazolyl-pyrazoline derivatives: In vitro and in silico evaluation as potential acetylcholinesterase and carbonic anhydrase inhibitors B Sever, C Türkeş, MD Altıntop, Y Demir, Ş Beydemir International Journal of Biological Macromolecules 163, 1970-1988, 2020 | 92 | 2020 |
Design, synthesis, and biological evaluation of novel 1, 3, 4-thiadiazole derivatives as potential antitumor agents against chronic myelogenous leukemia: Striking effect of … MD Altıntop, HI Ciftci, MO Radwan, B Sever, ZA Kaplancıklı, TFS Ali, ... Molecules 23 (1), 59, 2017 | 76 | 2017 |
Design, synthesis, in vitro and in silico evaluation of a new series of oxadiazole-based anticancer agents as potential Akt and FAK inhibitors MD Altıntop, B Sever, GA Çiftçi, G Turan-Zitouni, ZA Kaplancıklı, ... European journal of medicinal chemistry 155, 905-924, 2018 | 73 | 2018 |
Design, synthesis, in vitro and in silico investigation of aldose reductase inhibitory effects of new thiazole-based compounds B Sever, MD Altıntop, Y Demir, GA Çiftçi, Ş Beydemir, A Özdemir Bioorganic Chemistry 102, 104110, 2020 | 72 | 2020 |
Novel metabolic enzyme inhibitors designed through the molecular hybridization of thiazole and pyrazoline scaffolds B Sever, C Türkeş, MD Altıntop, Y Demir, G Akalın Çiftçi, Ş Beydemir Archiv der Pharmazie 354 (12), 2100294, 2021 | 71 | 2021 |
A new series of 2, 4-thiazolidinediones endowed with potent aldose reductase inhibitory activity B Sever, MD Altıntop, Y Demir, C Türkeş, K Özbaş, GA Çiftçi, Ş Beydemir, ... Open Chemistry 19 (1), 347-357, 2021 | 67 | 2021 |
Design, synthesis, and evaluation of a new series of thiazole-based anticancer agents as potent Akt inhibitors MD Altıntop, B Sever, G Akalın Çiftçi, A Özdemir Molecules 23 (6), 1318, 2018 | 61 | 2018 |
Comprehensive research on past and future therapeutic strategies devoted to treatment of amyotrophic lateral sclerosis B Sever, H Ciftci, H DeMirci, H Sever, F Ocak, B Yulug, H Tateishi, ... International journal of molecular sciences 23 (5), 2400, 2022 | 57 | 2022 |
Indomethacin based new triazolothiadiazine derivatives: Synthesis, evaluation of their anticancer effects on T98 human glioma cell line related to COX-2 inhibition and docking … B Sever, MD Altıntop, G Kuş, M Özkurt, A Özdemir, ZA Kaplancıklı European Journal of Medicinal Chemistry 113, 179-186, 2016 | 57 | 2016 |
An extensive research on aldose reductase inhibitory effects of new 4H-1, 2, 4-triazole derivatives B Sever, MD Altıntop, Y Demir, M Pekdoğan, GA Çiftçi, Ş Beydemir, ... Journal of Molecular Structure 1224, 129446, 2021 | 51 | 2021 |
A new series of pyrrole-based chalcones: synthesis and evaluation of antimicrobial activity, cytotoxicity, and genotoxicity A Özdemir, MD Altıntop, B Sever, H Karaca Gençer, HA Kapkaç, Ö Atlı, ... Molecules 22 (12), 2112, 2017 | 50 | 2017 |
Identification of a new class of potent aldose reductase inhibitors: Design, microwave-assisted synthesis, in vitro and in silico evaluation of 2-pyrazolines B Sever, MD Altıntop, Y Demir, N Yılmaz, GA Çiftçi, Ş Beydemir, ... Chemico-Biological Interactions 345, 109576, 2021 | 48 | 2021 |
Synthesis and evaluation of new benzodioxole-based thiosemicarbazone derivatives as potential antitumor agents MD Altıntop, HE Temel, B Sever, G Akalın Çiftçi, ZA Kaplancıklı Molecules 21 (11), 1598, 2016 | 45 | 2016 |
Synthesis and evaluation of new oxadiazole, thiadiazole, and triazole derivatives as potential anticancer agents targeting MMP-9 A Özdemir, B Sever, MD Altıntop, HE Temel, Ö Atlı, M Baysal, F Demirci Molecules 22 (7), 1109, 2017 | 44 | 2017 |
Synthesis and evaluation of new benzodioxole-based dithiocarbamate derivatives as potential anticancer agents and hCA-I and hCA-II inhibitors MD Altıntop, B Sever, GA Çiftçi, K Kucukoglu, A Özdemir, SS Soleimani, ... European Journal of Medicinal Chemistry 125, 190-196, 2017 | 42 | 2017 |
In vitro and in silico evaluation of anticancer activity of new indole-based 1, 3, 4-oxadiazoles as EGFR and COX-2 inhibitors B Sever, MD Altıntop, A Özdemir, G Akalın Çiftçi, DE Ellakwa, H Tateishi, ... Molecules 25 (21), 5190, 2020 | 41 | 2020 |
Synthesis and In Vitro Evaluation of New Thiosemicarbazone Derivatives as Potential Antimicrobial Agents ZA Kaplancıklı, MD Altıntop, B Sever, Z Cantürk, A Özdemir Journal of Chemistry 2016 (1), 1692540, 2016 | 36 | 2016 |
Potential inhibitors of human carbonic anhydrase isozymes I and II: Design, synthesis and docking studies of new 1, 3, 4-thiadiazole derivatives MD Altıntop, B Sever, A Özdemir, K Kucukoglu, H Onem, H Nadaroglu, ... Bioorganic & Medicinal Chemistry 25 (13), 3547-3554, 2017 | 33 | 2017 |
Synthesis and evaluation of naphthalene-based thiosemicarbazone derivatives as new anticancer agents against LNCaP prostate cancer cells MD Altintop, B Sever, A Özdemir, G Kuş, P Oztopcu-Vatan, S Kabadere, ... Journal of enzyme inhibition and medicinal chemistry 31 (3), 410-416, 2016 | 32 | 2016 |