Dynamic landscape of immune cell-specific gene regulation in immune-mediated diseases M Ota, Y Nagafuchi, H Hatano, K Ishigaki, C Terao, Y Takeshima, ... Cell 184 (11), 3006-3021. e17, 2021 | 221 | 2021 |
Polygenic burdens on cell-specific pathways underlie the risk of rheumatoid arthritis K Ishigaki, Y Kochi, A Suzuki, Y Tsuchida, H Tsuchiya, S Sumitomo, ... Nature genetics 49 (7), 1120-1125, 2017 | 154 | 2017 |
Clinical and immunological biomarkers for systemic lupus erythematosus H Yu, Y Nagafuchi, K Fujio Biomolecules 11 (7), 928, 2021 | 138 | 2021 |
Distinct transcriptome architectures underlying lupus establishment and exacerbation M Nakano, M Ota, Y Takeshima, Y Iwasaki, H Hatano, Y Nagafuchi, ... Cell 185 (18), 3375-3389. e21, 2022 | 69 | 2022 |
Immunophenotyping of rheumatoid arthritis reveals a linkage between HLA-DRB1 genotype, CXCR4 expression on memory CD4+ T cells and disease activity Y Nagafuchi, H Shoda, S Sumitomo, S Nakachi, R Kato, Y Tsuchida, ... Scientific reports 6 (1), 29338, 2016 | 67 | 2016 |
Interleukin-10-producing LAG3+ regulatory T cells are associated with disease activity and abatacept treatment in rheumatoid arthritis S Nakachi, S Sumitomo, Y Tsuchida, H Tsuchiya, M Kono, R Kato, ... Arthritis research & therapy 19, 1-11, 2017 | 61 | 2017 |
Increased serum concentrations of IL-1 beta, IL-21 and Th17 cells in overweight patients with rheumatoid arthritis H Shoda, Y Nagafuchi, Y Tsuchida, K Sakurai, S Sumitomo, K Fujio, ... Arthritis research & therapy 19, 1-9, 2017 | 52 | 2017 |
Immune profiling and precision medicine in systemic lupus erythematosus Y Nagafuchi, H Shoda, K Fujio Cells 8 (2), 140, 2019 | 45 | 2019 |
Efficacy of intensive immunosuppression in exacerbated rheumatoid arthritis-associated interstitial lung disease M Ota, Y Iwasaki, H Harada, O Sasaki, Y Nagafuchi, S Nakachi, ... Modern Rheumatology 27 (1), 22-28, 2017 | 44 | 2017 |
A case of refractory polyarteritis nodosa successfully treated with rituximab Y Seri, H Shoda, N Hanata, Y Nagafuchi, S Sumitomo, K Fujio, ... Modern Rheumatology 27 (4), 696-698, 2017 | 40 | 2017 |
Splicing QTL analysis focusing on coding sequences reveals mechanisms for disease susceptibility loci K Yamaguchi, K Ishigaki, A Suzuki, Y Tsuchida, H Tsuchiya, S Sumitomo, ... Nature communications 13 (1), 4659, 2022 | 38 | 2022 |
Immune cell multiomics analysis reveals contribution of oxidative phosphorylation to B-cell functions and organ damage of lupus Y Takeshima, Y Iwasaki, M Nakano, Y Narushima, M Ota, Y Nagafuchi, ... Annals of the rheumatic diseases 81 (6), 845-853, 2022 | 38 | 2022 |
Transcriptome analysis of peripheral blood from patients with rheumatoid arthritis: a systematic review S Sumitomo, Y Nagafuchi, Y Tsuchida, H Tsuchiya, M Ota, K Ishigaki, ... Inflammation and Regeneration 38, 1-5, 2018 | 36 | 2018 |
HLA-DRB1 shared epitope alleles and disease activity are correlated with reduced T cell receptor repertoire diversity in CD4+ T cells in rheumatoid arthritis K Sakurai, K Ishigaki, H Shoda, Y Nagafuchi, Y Tsuchida, S Sumitomo, ... The Journal of Rheumatology 45 (7), 905-914, 2018 | 33 | 2018 |
Integrated bulk and single-cell RNA-sequencing identified disease-relevant monocytes and a gene network module underlying systemic sclerosis S Kobayashi, Y Nagafuchi, M Okubo, Y Sugimori, H Shirai, H Hatano, ... Journal of Autoimmunity 116, 102547, 2021 | 30 | 2021 |
Autoantigen BiP‐derived HLA–DR4 epitopes differentially recognized by effector and regulatory T cells in rheumatoid arthritis H Shoda, K Fujio, K Sakurai, K Ishigaki, Y Nagafuchi, M Shibuya, ... Arthritis & Rheumatology 67 (5), 1171-1181, 2015 | 30 | 2015 |
The impact of obesity and a high-fat diet on clinical and immunological features in systemic lupus erythematosus M Kono, Y Nagafuchi, H Shoda, K Fujio Nutrients 13 (2), 504, 2021 | 29 | 2021 |
Immunomics analysis of rheumatoid arthritis identified precursor dendritic cells as a key cell subset of treatment resistance S Yamada, Y Nagafuchi, M Wang, M Ota, H Hatano, Y Takeshima, ... Annals of the rheumatic diseases 82 (6), 809-819, 2023 | 28 | 2023 |
A gene module associated with dysregulated TCR signaling pathways in CD4+ T cell subsets in rheumatoid arthritis S Sumitomo, Y Nagafuchi, Y Tsuchida, H Tsuchiya, M Ota, K Ishigaki, ... Journal of autoimmunity 89, 21-29, 2018 | 27 | 2018 |
CD4+CD25+LAG3+ T Cells With a Feature of Th17 Cells Associated With Systemic Lupus Erythematosus Disease Activity R Kato, S Sumitomo, Y Tsuchida, H Tsuchiya, S Nakachi, K Sakurai, ... Frontiers in immunology 10, 1619, 2019 | 26 | 2019 |