| Molecular basis for pore blockade of human Na+ channel Nav1. 2 by the μ-conotoxin KIIIA X Pan, Z Li, X Huang, G Huang, S Gao, H Shen, L Liu, J Lei, N Yan Science 363 (6433), 1309-1313, 2019 | 238 | 2019 |
| Molecular basis for ligand modulation of a mammalian voltage-gated Ca2+ channel Y Zhao, G Huang, J Wu, Q Wu, S Gao, Z Yan, J Lei, N Yan Cell 177 (6), 1495-1506. e12, 2019 | 228 | 2019 |
| Quasi-racemic X-ray structures of K27-linked ubiquitin chains prepared by total chemical synthesis M Pan, S Gao, Y Zheng, X Tan, H Lan, X Tan, D Sun, L Lu, T Wang, ... Journal of the American Chemical Society 138 (23), 7429-7435, 2016 | 210 | 2016 |
| Structure of human Cav2.2 channel blocked by the painkiller ziconotide S Gao, X Yao, N Yan Nature 596 (7870), 143-147, 2021 | 125 | 2021 |
| Practical chemical synthesis of atypical ubiquitin chains by using an isopeptide‐linked Ub isomer S Tang, LJ Liang, YY Si, S Gao, JX Wang, J Liang, Z Mei, JS Zheng, L Liu Angewandte Chemie 129 (43), 13518-13522, 2017 | 114 | 2017 |
| Synthesis of l‐ and d‐Ubiquitin by One‐Pot Ligation and Metal‐Free Desulfurization YC Huang, CC Chen, S Gao, YH Wang, H Xiao, F Wang, CL Tian, YM Li Chemistry–A European Journal 22 (22), 7623-7628, 2016 | 100 | 2016 |
| Inhibition of tetrameric Patched1 by Sonic Hedgehog through an asymmetric paradigm H Qian, P Cao, M Hu, S Gao, N Yan, X Gong Nature communications 10 (1), 2320, 2019 | 89 | 2019 |
| Structural basis for catalysis and substrate specificity of human ACAT1 H Qian, X Zhao, R Yan, X Yao, S Gao, X Sun, X Du, H Yang, CCL Wong, ... Nature 581 (7808), 333-338, 2020 | 87 | 2020 |
| Monomer/oligomer quasi-racemic protein crystallography S Gao, M Pan, Y Zheng, Y Huang, Q Zheng, D Sun, L Lu, X Tan, X Tan, ... Journal of the American Chemical Society 138 (43), 14497-14502, 2016 | 81 | 2016 |
| A structure of human Scap bound to Insig-2 suggests how their interaction is regulated by sterols R Yan, P Cao, W Song, H Qian, X Du, HW Coates, X Zhao, Y Li, S Gao, ... Science 371 (6533), eabb2224, 2021 | 70 | 2021 |
| Structural Basis of the Modulation of the Voltage‐Gated Calcium Ion Channel Cav1.1 by Dihydropyridine Compounds** S Gao, N Yan Angewandte Chemie 133 (6), 3168-3174, 2021 | 67 | 2021 |
| Structural basis of ion transport and inhibition in ferroportin Y Pan, Z Ren, S Gao, J Shen, L Wang, Z Xu, Y Yu, P Bachina, H Zhang, ... Nature communications 11 (1), 5686, 2020 | 62 | 2020 |
| Facile synthesis of C-terminal peptide hydrazide and thioester of NY-ESO-1 (A39-A68) from an Fmoc-hydrazine 2-chlorotrityl chloride resin YC Huang, CC Chen, SJ Li, S Gao, J Shi, YM Li Tetrahedron 70 (18), 2951-2955, 2014 | 62 | 2014 |
| Synthesis of disulfide surrogate peptides incorporating large‐span surrogate bridges through a native chemical ligation‐assisted diaminodiacid strategy Q Qu, S Gao, F Wu, MG Zhang, Y Li, LH Zhang, C Tian, JS Zheng, L Liu Angewandte Chemie International Edition, 2020 | 61 | 2020 |
| Employing NaChBac for cryo-EM analysis of toxin action on voltage-gated Na+ channels in nanodisc S Gao, WC Valinsky, NC On, PR Houlihan, Q Qu, L Liu, X Pan, ... Proceedings of the National Academy of Sciences 117 (25), 14187-14193, 2020 | 48 | 2020 |
| Structural basis for pore blockade of human voltage-gated calcium channel Cav1.3 by motion sickness drug cinnarizine X Yao, S Gao, N Yan Cell Research 32 (10), 946-948, 2022 | 47 | 2022 |
| Sortase-mediated chemical protein synthesis reveals the bidentate binding of bisphosphorylated p62 with K63 diubiquitin XL Tan, M Pan, Y Zheng, S Gao, LJ Liang, YM Li Chemical Science 8 (10), 6881-6887, 2017 | 34 | 2017 |
| Chemical synthesis of structurally defined phosphorylated ubiquitins suggests impaired parkin activation by phosphorylated ubiquitins with a non-phosphorylated distal unit M Pan, Q Zheng, S Gao, Q Qu, Y Yu, M Wu, H Lan, Y Li, S Liu, J Li, D Sun, ... CCS Chemistry 1 (5), 476-489, 2019 | 32 | 2019 |
| A highly efficient synthesis of polyubiquitin chains Q Qu, M Pan, S Gao, QY Zheng, YY Yu, JC Su, X Li, HG Hu Advanced science 5 (7), 1800234, 2018 | 25 | 2018 |
| Racemic X-ray structure of L-type calcium channel antagonist Calciseptine prepared by total chemical synthesis CC Chen, S Gao, HS Ai, Q Qu, CL Tian, YM Li Science China Chemistry 61, 702-707, 2018 | 24 | 2018 |
Nieng YanShenzhen Medical Academy of Research & Translation (SMART) / Tsinghua University / PrincetonPotvrđena adresa e-pošte na smart.org.cn
