Regulatory circuitry governing fungal development, drug resistance, and disease RS Shapiro, N Robbins, LE Cowen Microbiology and molecular biology reviews 75 (2), 213-267, 2011 | 736 | 2011 |
Antifungal Drug Resistance: Molecular Mechanisms in Candida albicans and Beyond Y Lee, E Puumala, N Robbins, LE Cowen Chemical reviews 121 (6), 3390-3411, 2020 | 620 | 2020 |
Antifungal drug resistance: evolution, mechanisms and impact NM Revie, KR Iyer, N Robbins, LE Cowen Current opinion in microbiology 45, 70-76, 2018 | 538 | 2018 |
Molecular evolution of antifungal drug resistance N Robbins, T Caplan, LE Cowen Annual review of microbiology 71 (1), 753-775, 2017 | 425 | 2017 |
Hsp90 Governs Echinocandin Resistance in the Pathogenic Yeast Candida albicans via Calcineurin SD Singh, N Robbins, AK Zaas, WA Schell, JR Perfect, LE Cowen PLoS pathogens 5 (7), e1000532, 2009 | 415 | 2009 |
Hsp90 governs dispersion and drug resistance of fungal biofilms N Robbins, P Uppuluri, J Nett, R Rajendran, G Ramage, JL Lopez-Ribot, ... PLoS pathogens 7 (9), e1002257, 2011 | 347 | 2011 |
Antifungal drugs: the current armamentarium and development of new agents N Robbins, GD Wright, LE Cowen Microbiology spectrum 4 (5), 10.1128/microbiolspec. funk-0002-2016, 2016 | 260 | 2016 |
Treatment strategies for cryptococcal infection: challenges, advances and future outlook KR Iyer, NM Revie, C Fu, N Robbins, LE Cowen Nature Reviews Microbiology 19 (7), 454-466, 2021 | 250 | 2021 |
Combinatorial strategies for combating invasive fungal infections M Spitzer, N Robbins, GD Wright Virulence 8 (2), 169-185, 2017 | 213 | 2017 |
Lysine deacetylases Hda1 and Rpd3 regulate Hsp90 function thereby governing fungal drug resistance N Robbins, MD Leach, LE Cowen Cell reports 2 (4), 878-888, 2012 | 135 | 2012 |
Genetic Analysis of Candida auris Implicates Hsp90 in Morphogenesis and Azole Tolerance and Cdr1 in Azole Resistance SH Kim, KR Iyer, L Pardeshi, JF Muñoz, N Robbins, CA Cuomo, KH Wong, ... MBio 10 (1), 10.1128/mbio. 02529-18, 2019 | 134 | 2019 |
Structural basis for species-selective targeting of Hsp90 in a pathogenic fungus L Whitesell, N Robbins, DS Huang, CA McLellan, T Shekhar-Guturja, ... Nature communications 10 (1), 402, 2019 | 113 | 2019 |
The Hsp90 chaperone network modulates Candida virulence traits TR O’Meara, N Robbins, LE Cowen Trends in microbiology 25 (10), 809-819, 2017 | 97 | 2017 |
A small molecule produced by Lactobacillus species blocks Candida albicans filamentation by inhibiting a DYRK1-family kinase J MacAlpine, M Daniel-Ivad, Z Liu, J Yano, NM Revie, RT Todd, ... Nature communications 12 (1), 6151, 2021 | 95 | 2021 |
Molecular mechanisms governing antifungal drug resistance Y Lee, N Robbins, LE Cowen npj Antimicrobials and Resistance 1 (1), 5, 2023 | 89 | 2023 |
An antifungal combination matrix identifies a rich pool of adjuvant molecules that enhance drug activity against diverse fungal pathogens N Robbins, M Spitzer, T Yu, RP Cerone, AK Averette, YS Bahn, J Heitman, ... Cell reports 13 (7), 1481-1492, 2015 | 81 | 2015 |
Leveraging machine learning essentiality predictions and chemogenomic interactions to identify antifungal targets C Fu, X Zhang, AO Veri, KR Iyer, E Lash, A Xue, H Yan, NM Revie, ... Nature communications 12 (1), 6497, 2021 | 69 | 2021 |
Design and synthesis of fungal-selective resorcylate aminopyrazole Hsp90 inhibitors DS Huang, EV LeBlanc, T Shekhar-Guturja, N Robbins, DJ Krysan, ... Journal of medicinal chemistry 63 (5), 2139-2180, 2019 | 66 | 2019 |
Functional genomic screening reveals core modulators of echinocandin stress responses in Candida albicans T Caplan, EJ Polvi, JL Xie, S Buckhalter, MD Leach, N Robbins, ... Cell reports 23 (8), 2292-2298, 2018 | 65 | 2018 |
The Candida albicans transcription factor Cas5 couples stress responses, drug resistance and cell cycle regulation JL Xie, L Qin, Z Miao, BT Grys, JDLC Diaz, K Ting, JR Krieger, J Tong, ... Nature communications 8 (1), 499, 2017 | 65 | 2017 |