| P450 BM3: the very model of a modern flavocytochrome AW Munro, DG Leys, KJ McLean, KR Marshall, TWB Ost, S Daff, CS Miles, ... Trends in biochemical sciences 27 (5), 250-257, 2002 | 528 | 2002 |
| Variations on a (t) heme—novel mechanisms, redox partners and catalytic functions in the cytochrome P450 superfamily AW Munro, HM Girvan, KJ McLean Natural product reports 24 (3), 585-609, 2007 | 342 | 2007 |
| Cytochrome P450–redox partner fusion enzymes AW Munro, HM Girvan, KJ McLean Biochimica et Biophysica Acta (BBA)-General Subjects 1770 (3), 345-359, 2007 | 282 | 2007 |
| What makes a P450 tick? AW Munro, HM Girvan, AE Mason, AJ Dunford, KJ McLean Trends in Biochemical Sciences 38 (3), 140-150, 2013 | 241 | 2013 |
| Azole antifungals are potent inhibitors of cytochrome P450 mono-oxygenases and bacterial growth in mycobacteria and streptomycetes KJ McLean, KR Marshall, A Richmond, IS Hunter, K Fowler, T Kieser, ... Microbiology 148 (10), 2937-2949, 2002 | 224 | 2002 |
| Structure and biochemical properties of the alkene producing cytochrome P450 OleTJE (CYP152L1) from the Jeotgalicoccus sp. 8456 bacterium J Belcher, KJ McLean, S Matthews, LS Woodward, K Fisher, SEJ Rigby, ... Journal of Biological Chemistry 289 (10), 6535-6550, 2014 | 213 | 2014 |
| Structure and function of the cytochrome P450 peroxygenase enzymes AW Munro, KJ McLean, JL Grant, TM Makris Biochemical Society Transactions 46 (1), 183-196, 2018 | 208 | 2018 |
| Atomic structure of Mycobacterium tuberculosis CYP121 to 1.06 Å reveals novel features of cytochrome P450 D Leys, CG Mowat, KJ McLean, A Richmond, SK Chapman, ... Journal of Biological Chemistry 278 (7), 5141-5147, 2003 | 196 | 2003 |
| Biodiversity of cytochrome P450 redox systems KJ McLean, M Sabri, KR Marshall, RJ Lawson, DG Lewis, D Clift, ... Biochemical Society Transactions 33 (4), 796-801, 2005 | 174 | 2005 |
| Single-step fermentative production of the cholesterol-lowering drug pravastatin via reprogramming of Penicillium chrysogenum KJ McLean, M Hans, B Meijrink, WB Van Scheppingen, A Vollebregt, ... Proceedings of the National Academy of Sciences 112 (9), 2847-2852, 2015 | 167 | 2015 |
| Characterization of active site structure in CYP121: A cytochrome P450 essential for viability of Mycobacterium tuberculosis H37Rv KJ McLean, P Carroll, DG Lewis, AJ Dunford, HE Seward, R Neeli, ... Journal of Biological Chemistry 283 (48), 33406-33416, 2008 | 156 | 2008 |
| P450-catalyzed regio-and diastereoselective steroid hydroxylation: efficient directed evolution enabled by mutability landscaping CG Acevedo-Rocha, CG Gamble, R Lonsdale, A Li, N Nett, ... Acs Catalysis 8 (4), 3395-3410, 2018 | 151 | 2018 |
| The structure of Mycobacterium tuberculosis CYP125 KJ McLean, P Lafite, C Levy, MR Cheesman, N Mast, IA Pikuleva, D Leys, ... Journal of Biological Chemistry 284 (51), 35524-35533, 2009 | 151 | 2009 |
| Crystal structure of the Mycobacterium tuberculosis P450 CYP121-fluconazole complex reveals new azole drug-P450 binding mode HE Seward, A Roujeinikova, KJ McLean, AW Munro, D Leys Journal of Biological Chemistry 281 (51), 39437-39443, 2006 | 147 | 2006 |
| Structural and biochemical characterization of Mycobacterium tuberculosis CYP142: evidence for multiple cholesterol 27-hydroxylase activities in a human pathogen MD Driscoll, KJ McLean, C Levy, N Mast, IA Pikuleva, P Lafite, SEJ Rigby, ... Journal of biological chemistry 285 (49), 38270-38282, 2010 | 138 | 2010 |
| The TB structural genomics consortium: a resource for Mycobacterium tuberculosis biology TC Terwilliger, MS Park, GS Waldo, J Berendzen, LW Hung, CY Kim, ... Tuberculosis 83 (4), 223-249, 2003 | 137 | 2003 |
| Flavocytochrome P450 BM3: an update on structure and mechanism of a biotechnologically important enzyme AJ Warman, O Roitel, R Neeli, HM Girvan, HE Seward, SA Murray, ... Biochemical Society Transactions 33 (4), 747-753, 2005 | 136 | 2005 |
| Expression, purification and spectroscopic characterization of the cytochrome P450 CYP121 from Mycobacterium tuberculosis KJ McLean, MR Cheesman, SL Rivers, A Richmond, D Leys, ... Journal of inorganic biochemistry 91 (4), 527-541, 2002 | 128 | 2002 |
| How do azoles inhibit cytochrome P450 enzymes? A density functional study PR Balding, CS Porro, KJ McLean, MJ Sutcliffe, JD Maréchal, AW Munro, ... The Journal of Physical Chemistry A 112 (50), 12911-12918, 2008 | 107 | 2008 |
| Biophysical Characterization of the Sterol Demethylase P450 from Mycobacterium tuberculosis, Its Cognate Ferredoxin, and Their Interactions KJ McLean, AJ Warman, HE Seward, KR Marshall, HM Girvan, ... Biochemistry 45 (27), 8427-8443, 2006 | 107 | 2006 |
