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The immunopathology of sepsis and potential therapeutic targets
T van der Poll, FL Van De Veerdonk, BP Scicluna, MG Netea
Nature Reviews Immunology 17 (7), 407-420, 2017
17062017
The gut microbiota plays a protective role in the host defence against pneumococcal pneumonia
TJ Schuijt, JM Lankelma, BP Scicluna, FS e Melo, JJTH Roelofs, ...
Gut 65 (4), 575-583, 2016
8002016
Incidence, risk factors, and attributable mortality of secondary infections in the intensive care unit after admission for sepsis
LA van Vught, PMCK Klouwenberg, C Spitoni, BP Scicluna, MA Wiewel, ...
Jama 315 (14), 1469-1479, 2016
5742016
Broad defects in the energy metabolism of leukocytes underlie immunoparalysis in sepsis
SC Cheng, BP Scicluna, RJW Arts, MS Gresnigt, E Lachmandas, ...
Nature immunology 17 (4), 406-413, 2016
5692016
Classification of patients with sepsis according to blood genomic endotype: a prospective cohort study
BP Scicluna, LA Van Vught, AH Zwinderman, MA Wiewel, EE Davenport, ...
The Lancet Respiratory Medicine 5 (10), 816-826, 2017
5102017
The itaconate pathway is a central regulatory node linking innate immune tolerance and trained immunity
J Domínguez-Andrés, B Novakovic, Y Li, BP Scicluna, MS Gresnigt, ...
Cell metabolism 29 (1), 211-220. e5, 2019
3312019
Thrombocytopenia is associated with a dysregulated host response in critically ill sepsis patients
TAM Claushuis, LA van Vught, BP Scicluna, MA Wiewel, ...
Blood, The Journal of the American Society of Hematology 127 (24), 3062-3072, 2016
3252016
Genome-wide association study identifies a susceptibility locus at 21q21 for ventricular fibrillation in acute myocardial infarction
CR Bezzina, R Pazoki, A Bardai, RF Marsman, JSSG De Jong, MT Blom, ...
Nature genetics 42 (8), 688-691, 2010
2472010
Myocyte necrosis underlies progressive myocardial dystrophy in mouse dsg2-related arrhythmogenic right ventricular cardiomyopathy
K Pilichou, CA Remme, C Basso, ME Campian, S Rizzo, P Barnett, ...
Journal of Experimental Medicine 206 (8), 1787-1802, 2009
2452009
A molecular biomarker to diagnose community-acquired pneumonia on intensive care unit admission
BP Scicluna, PMC Klein Klouwenberg, LA van Vught, MA Wiewel, ...
American journal of respiratory and critical care medicine 192 (7), 826-835, 2015
2242015
A molecular host response assay to discriminate between sepsis and infection-negative systemic inflammation in critically ill patients: discovery and validation in independent …
L McHugh, TA Seldon, RA Brandon, JT Kirk, A Rapisarda, AJ Sutherland, ...
PLoS medicine 12 (12), e1001916, 2015
2222015
36th international symposium on intensive care and emergency medicine: Brussels, Belgium. 15-18 March 2016
RM Bateman, MD Sharpe, JE Jagger, CG Ellis, J Solé-Violán, ...
Critical care 20, 13-182, 2016
2002016
Biomarkers in sepsis
TSR Van Engelen, WJ Wiersinga, BP Scicluna, T van der Poll
Critical care clinics 34 (1), 139-152, 2018
1912018
Functional NaV1.8 Channels in Intracardiac Neurons: The Link Between SCN10A and Cardiac Electrophysiology
AO Verkerk, CA Remme, CA Schumacher, BP Scicluna, R Wolswinkel, ...
Circulation research 111 (3), 333-343, 2012
1752012
Apc-mutant cells act as supercompetitors in intestinal tumour initiation
SM van Neerven, NE de Groot, LE Nijman, BP Scicluna, MS van Driel, ...
Nature 594 (7863), 436-441, 2021
1722021
The cardiac sodium channel displays differential distribution in the conduction system and transmural heterogeneity in the murine ventricular myocardium
CA Remme, AO Verkerk, WMH Hoogaars, WTJ Aanhaanen, BP Scicluna, ...
Basic research in cardiology 104, 511-522, 2009
1402009
Load-reducing therapy prevents development of arrhythmogenic right ventricular cardiomyopathy in plakoglobin-deficient mice
L Fabritz, MG Hoogendijk, BP Scicluna, SCM Van Amersfoorth, ...
Journal of the American College of Cardiology 57 (6), 740-750, 2011
1392011
Sepsis subclasses: a framework for development and interpretation
KM DeMerle, DC Angus, JK Baillie, E Brant, CS Calfee, J Carcillo, ...
Critical care medicine 49 (5), 748-759, 2021
1362021
Admission hyperglycemia in critically ill sepsis patients: association with outcome and host response
LA van Vught, MA Wiewel, PMCK Klouwenberg, AJ Hoogendijk, ...
Critical care medicine 44 (7), 1338-1346, 2016
1342016
Understanding heterogeneity in biologic phenotypes of acute respiratory distress syndrome by leukocyte expression profiles
LDJ Bos, BP Scicluna, DSY Ong, O Cremer, T van Der Poll, MJ Schultz
American Journal of Respiratory and Critical Care Medicine 200 (1), 42-50, 2019
1262019
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