Prati
Karol R. Francisco
Karol R. Francisco
Potvrđena adresa e-pošte na ucsd.edu
Naslov
Citirano
Citirano
Godina
1, 2, 4-Triazolo [1, 5-a] pyrimidines in drug design
K Oukoloff, B Lucero, KR Francisco, KR Brunden, C Ballatore
European journal of medicinal chemistry 165, 332-346, 2019
1222019
Evaluation of log P, pKa, and log D predictions from the SAMPL7 blind challenge
TD Bergazin, N Tielker, Y Zhang, J Mao, MR Gunner, K Francisco, ...
Journal of computer-aided molecular design 35 (7), 771-802, 2021
722021
Structure property relationships of N-acylsulfonamides and related bioisosteres
KR Francisco, C Varricchio, TJ Paniak, MC Kozlowski, A Brancale, ...
European journal of medicinal chemistry 218, 113399, 2021
322021
Interplay between magnetoresistance and Kondo resonance in radical single-molecule junctions
G Mitra, JZ Low, S Wei, KR Francisco, M Deffner, C Herrmann, ...
Nano Letters 22 (14), 5773-5779, 2022
162022
Protein–protein interactions: developing small-molecule inhibitors/stabilizers through covalent strategies
B Lucero, KR Francisco, LJ Liu, CR Caffrey, C Ballatore
Trends in pharmacological sciences 44 (7), 474-488, 2023
142023
Microtubule-Stabilizing 1,2,4-Triazolo[1,5-a]pyrimidines as Candidate Therapeutics for Neurodegenerative Disease: Matched Molecular Pair Analyses and …
T Alle, C Varricchio, Y Yao, B Lucero, G Nzou, S Demuro, M Muench, ...
Journal of Medicinal Chemistry 66 (1), 435-459, 2022
142022
Structure-activity relationship of dibenzylideneacetone analogs against the neglected disease pathogen, Trypanosoma brucei
KR Francisco, L Monti, W Yang, H Park, LJ Liu, K Watkins, ...
Bioorganic & medicinal chemistry letters 81, 129123, 2023
122023
Activity of N-phenylbenzamide analogs against the neglected disease pathogen, Schistosoma mansoni
M Kanyanta, C Lengwe, D Mambwe, KR Francisco, LJ Liu, YU Sun, ...
Bioorganic & medicinal chemistry letters 82, 129164, 2023
92023
A Broad Spectrum Antiparasitic Activity of Organotin (IV) Derivatives and Its Untargeted Proteomic Profiling Using Leishmania donovani
O Hayat, N Ullah, M Sirajuddin, MA Giardini, JV Nguyen, KR Francisco, ...
Pathogens 11 (12), 1424, 2022
82022
Inhibition of the HEG1–KRIT1 interaction increases KLF4 and KLF2 expression in endothelial cells
MA Lopez‐Ramirez, S McCurdy, W Li, MK Haynes, P Hale, K Francisco, ...
Faseb Bioadvances 3 (5), 334, 2021
82021
Thietanes and Derivatives thereof in Medicinal Chemistry
KR Francisco, C Ballatore
Current Topics in Medicinal Chemistry 22 (15), 1219-1234, 2022
72022
Structure-property relationships of fluorinated carboxylic acid bioisosteres
T Alle, S Joyasawal, K Oukoloff, K Long, Z Owyang, KR Francisco, ...
Bioorganic & medicinal chemistry letters 91, 129363, 2023
52023
Targeted Reversible Covalent Modification of a Noncatalytic Lysine of the Krev Interaction Trapped 1 Protein Enables Site-Directed Screening for Protein–Protein Interaction …
KR Francisco, J Bruystens, C Varricchio, S McCurdy, J Wu, ...
ACS Pharmacology & Translational Science 6 (11), 1651-1658, 2023
42023
Hydrogen Bonding Parameters by Rapid Colorimetric Assessment: Evaluation of Structural Components Found in Biological Ligands and Organocatalysts
HF Roenfanz, TJ Paniak, CB Berlin, V Tran, KR Francisco, P Lassalas, ...
Chemistry–A European Journal 29 (40), e202300696, 2023
32023
Synthesis of a C-7 Pd-glycosyl-donor via the base promoted alkylative CO2 trapping with 2-acetylfuran
KR Francisco, Y Li, B Lindquist-Kleissler, J Zheng, Y Xing, GA O’Doherty
Journal of CO2 Utilization 54, 101774, 2021
32021
Tractable Quinolone Hydrazides Exhibiting Sub‐Micromolar and Broad Spectrum Antitrypanosomal Activities
KA Chirwa, KR Francisco, PS Dube, H Park, LJ Legoabe, TR Teixeira, ...
ChemMedChem 19 (9), e202300667, 2024
22024
Design, Synthesis, and Evaluation of An Anti‐trypanosomal [1,2,4]Triazolo[1,5‐a]pyrimidine Probe for Photoaffinity Labeling Studies
B Lucero, KR Francisco, C Varricchio, LJ Liu, Y Yao, A Brancale, ...
ChemMedChem 19 (8), e202300656, 2024
22024
Structure activity relationships of antischistosomal N-phenylbenzamides by incorporation of electron-withdrawing functionalities
AM Dawoodjee, J Sichinga, H Banda, S Mbaya, E Funjika, G Mayoka, ...
Results in Chemistry 12, 101890, 2024
2024
Carmaphycin B-Based Proteasome Inhibitors to Treat Human African Trypanosomiasis: Structure–Activity Relationship and In Vivo Efficacy
LJ Liu, KR Francisco, YU Sun, MSM Serafim, DK Amarasinghe, ...
ACS Infectious Diseases 10 (12), 4182-4193, 2024
2024
Clickable Probes for Pathogen Proteasomes: Synthesis and Applications
LJ Liu, B Lucero, C Manriquez-Rodriguez, KR Francisco, TR Teixeira, ...
ACS omega 9 (32), 34829-34840, 2024
2024
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