Prati
Vlad-Stefan Raducanu
Vlad-Stefan Raducanu
Associate Principal Scientist at AstraZeneca
Potvrđena adresa e-pošte na astrazeneca.com - Početna stranica
Naslov
Citirano
Citirano
Godina
Structure of the processive human Pol δ holoenzyme
C Lancey, M Tehseen, VS Raducanu, F Rashid, N Merino, TJ Ragan, ...
Nature communications 11 (1), 1109, 2020
1472020
Initial state of DNA-Dye complex sets the stage for protein induced fluorescence modulation
F Rashid, VS Raducanu, MS Zaher, M Tehseen, S Habuchi, SM Hamdan
Nature communications 10 (1), 2104, 2019
732019
A direct fluorescent signal transducer embedded in a DNA aptamer paves the way for versatile metal-ion detection
VS Raducanu, F Rashid, MS Zaher, Y Li, JS Merzaban, SM Hamdan
Sensors and Actuators B: Chemical 304, 127376, 2020
322020
Cryo-EM structure of human Pol κ bound to DNA and mono-ubiquitylated PCNA
C Lancey, M Tehseen, S Bakshi, M Percival, M Takahashi, MA Sobhy, ...
Nature Communications 12 (1), 6095, 2021
312021
Two chromatographic schemes for protein purification involving the biotin/avidin interaction under native conditions
VS Raducanu, M Tehseen, A Shirbini, DV Raducanu, SM Hamdan
Journal of Chromatography A 1621, 461051, 2020
272020
Resolution of the Holliday junction recombination intermediate by human GEN1 at the single-molecule level
MA Sobhy, A Bralić, VS Raducanu, M Takahashi, M Tehseen, F Rashid, ...
Nucleic Acids Research 47 (4), 1935-1949, 2019
252019
Proliferating cell nuclear antigen-agarose column: A tag-free and tag-dependent tool for protein purification affinity chromatography
M Tehseen, VS Raducanu, F Rashid, A Shirbini, M Takahashi, ...
Journal of Chromatography A 1602, 341-349, 2019
242019
What is all this fuss about Tus? Comparison of recent findings from biophysical and biochemical experiments
BA Berghuis, VS Raducanu, MM Elshenawy, S Jergic, M Depken, ...
Critical Reviews in Biochemistry and Molecular Biology 53 (1), 49-63, 2018
232018
Mechanism of human Lig1 regulation by PCNA in Okazaki fragment sealing
K Blair, M Tehseen, VS Raducanu, T Shahid, C Lancey, F Rashid, ...
Nature communications 13 (1), 7833, 2022
222022
Simplified detection of polyhistidine-tagged proteins in gels and membranes using a UV-excitable dye and a multiple chelator head pair
VS Raducanu, I Isaioglou, DV Raducanu, JS Merzaban, SM Hamdan
Journal of Biological Chemistry 295 (34), 12214-12223, 2020
152020
Mechanistic investigation of human maturation of Okazaki fragments reveals slow kinetics
VS Raducanu, M Tehseen, A Al-Amodi, LI Joudeh, A De Biasio, ...
Nature Communications 13 (1), 6973, 2022
102022
TSGIT: An N‐and C‐terminal tandem tag system for purification of native and intein‐mediated ligation‐ready proteins
VS Raducanu, DV Raducanu, Y Ouyang, M Tehseen, M Takahashi, ...
Protein Science 30 (2), 497-512, 2021
102021
Single-Molecule Förster Resonance Energy Transfer Methods for Real-Time Investigation of the Holliday Junction Resolution by GEN1.
MA Sobhy, A Bralic, VS Raducanu, M Tehseen, Y Ouyang, M Takahashi, ...
MyJove Corporation, 2019
72019
Severe Combined Immunodeficiency from a Homozygous DNA Ligase 1 Mutant with Reduced Catalytic Activity but Increased Ligation Fidelity
H Alajlan, VS Raducanu, Y Lopez de los Santos, M Tehseen, H Alruwaili, ...
Journal of Clinical Immunology 44 (7), 151, 2024
42024
Single-molecule characterization of SV40 replisome and novel factors: human FPC and Mcm10
Y Ouyang, A Al-Amodi, M Tehseen, L Alhudhali, A Shirbini, M Takahashi, ...
Nucleic Acids Research 52 (15), 8880-8896, 2024
32024
Sliding clamp-based affinity purification systems, methods of making and use thereof
VS Raducanu, M Tehseen, F Rashid, SM Hamdan
US Patent App. 17/415,600, 2022
2022
Ligand detection by aptamers with a built-in reporter
MS Zaher, F Rashid, VS Raducanu, SM Hamdan
US Patent App. 17/278,386, 2022
2022
N-and c-terminal tandem tag system for purification
SM Hamdan, VS Raducanu
US Patent App. 17/408,328, 2022
2022
Methods for detecting his-tagged proteins using nta probes and polyacrylamide gel electrophoresis
VS Raducanu, I Isaioglou, JS Merzaban, SM Hamdan
US Patent App. 17/332,254, 2021
2021
Fluorescence tools for studying DNA-protein interactions with application in the investigation of Human Maturation of Okazaki Fragments
VS Raducanu
2021
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