RNA binding proteins co-localize with small tau inclusions in tauopathy BF Maziuk, DJ Apicco, AL Cruz, L Jiang, PEA Ash, EL da Rocha, C Zhang, ... Acta neuropathologica communications 6 (1), 1-14, 2018 | 134 | 2018 |
Interaction of tau with HNRNPA2B1 and N6-methyladenosine RNA mediates the progression of tauopathy L Jiang, W Lin, C Zhang, PEA Ash, M Verma, J Kwan, E van Vliet, Z Yang, ... Molecular cell 81 (20), 4209-4227. e12, 2021 | 128 | 2021 |
TIA1 potentiates tau phase separation and promotes generation of toxic oligomeric tau PEA Ash, S Lei, J Shattuck, S Boudeau, Y Carlomagno, M Medalla, ... Proceedings of the National Academy of Sciences 118 (9), e2014188118, 2021 | 119 | 2021 |
TIA1 regulates the generation and response to toxic tau oligomers L Jiang, PEA Ash, BF Maziuk, HI Ballance, S Boudeau, AA Abdullatif, ... Acta neuropathologica 137, 259-277, 2019 | 95 | 2019 |
Substance P exacerbates dopaminergic neurodegeneration through neurokinin-1 receptor-independent activation of microglial NADPH oxidase Q Wang, CH Chu, L Qian, SH Chen, B Wilson, E Oyarzabal, L Jiang, S Ali, ... Journal of Neuroscience 34 (37), 12490-12503, 2014 | 80 | 2014 |
Dysregulation of RNA splicing in tauopathies DJ Apicco, C Zhang, B Maziuk, L Jiang, HI Ballance, S Boudeau, C Ung, ... Cell reports 29 (13), 4377-4388. e4, 2019 | 69 | 2019 |
Loss of brain norepinephrine elicits neuroinflammation-mediated oxidative injury and selective caudo-rostral neurodegeneration S Song*, L Jiang*, EA Oyarzabal*, B Wilson, Z Li, YYI Shih, Q Wang, ... Molecular neurobiology 56 (4), 2653-2669, 2019 | 67 | 2019 |
A novel role of microglial NADPH oxidase in mediating extra‐synaptic function of norepinephrine in regulating brain immune homeostasis L Jiang, SH Chen, CH Chu, SJ Wang, E Oyarzabal, B Wilson, V Sanders, ... Glia 63 (6), 1057-1072, 2015 | 64 | 2015 |
Subpicomolar diphenyleneiodonium inhibits microglial NADPH oxidase with high specificity and shows great potential as a therapeutic agent for neurodegenerative diseases Q Wang, CH Chu, E Oyarzabal, L Jiang, SH Chen, B Wilson, L Qian, ... Glia 62 (12), 2034-2043, 2014 | 63 | 2014 |
Clozapine metabolites protect dopaminergic neurons through inhibition of microglial NADPH oxidase L Jiang, X Wu, S Wang, SH Chen, H Zhou, B Wilson, CY Jin, RB Lu, K Xie, ... Journal of neuroinflammation 13, 1-14, 2016 | 57 | 2016 |
Noradrenergic dysfunction accelerates LPS-elicited inflammation-related ascending sequential neurodegeneration and deficits in non-motor/motor functions S Song, Q Wang, L Jiang, E Oyarzabal, NV Riddick, B Wilson, SS Moy, ... Brain, behavior, and immunity 81, 374-387, 2019 | 44 | 2019 |
Diallyl sulfide protects against lipopolysaccharide/d-galactosamine-induced acute liver injury by inhibiting oxidative stress, inflammation and apoptosis in mice M Li, S Wang, X Li, L Jiang, X Wang, R Kou, Q Wang, L Xu, N Zhao, K Xie Food and Chemical Toxicology 120, 500-509, 2018 | 39 | 2018 |
Oxidative stress mediated hippocampal neuron apoptosis participated in carbon disulfide-induced rats cognitive dysfunction S Wang, G Irving, L Jiang, H Wang, M Li, X Wang, W Han, Y Xu, Y Yang, ... Neurochemical research 42, 583-594, 2017 | 34 | 2017 |
Identification of a specific α-synuclein peptide (α-Syn 29-40) capable of eliciting microglial superoxide production to damage dopaminergic neurons S Wang, CH Chu, M Guo, L Jiang, H Nie, W Zhang, B Wilson, L Yang, ... Journal of neuroinflammation 13, 1-19, 2016 | 28 | 2016 |
Single cell transcriptomic profiling of a neuron-astrocyte assembloid tauopathy model HD Rickner*, L Jiang*, R Hong, NK O’Neill, CA Mojica, BJ Snyder, ... Nature Communications 13 (6275), doi.org/10.1038/s41467-022-34005-1, 2022 | 25 | 2022 |
Diallyl trisulfide attenuated n-hexane induced neurotoxicity in rats by modulating P450 enzymes S Wang, M Li, X Wang, X Li, H Yin, L Jiang, W Han, G Irving, T Zeng, K Xie Chemico-Biological Interactions 265, 1-7, 2017 | 24 | 2017 |
Tau oligomers and fibrils exhibit differential patterns of seeding and association with RNA binding proteins L Jiang*, J Zhao*, JX Cheng, B Wolozin Frontiers in Neurology 11, 1183, 2020 | 23 | 2020 |
Involvement of decreased neuroglobin protein level in cognitive dysfunction induced by 1-bromopropane in rats Y Guo, H Yuan, L Jiang, J Yang, T Zeng, K Xie, C Zhang, X Zhao Brain Research 1600, 1-16, 2015 | 20 | 2015 |
Poly (GR) interacts with key stress granule factors promoting its assembly into cytoplasmic inclusions J Park, Y Wu, W Shao, TF Gendron, SJF van der Spek, G Sultanakhmetov, ... Cell reports 42 (8), 2023 | 17 | 2023 |
Acrylamide retards the slow axonal transport of neurofilaments in rat cultured dorsal root ganglia neurons and the corresponding mechanisms L An, G Li, J Si, C Zhang, X Han, S Wang, L Jiang, K Xie Neurochemical research 41, 1000-1009, 2016 | 17 | 2016 |