Metal complexes as a promising source for new antibiotics A Frei, J Zuegg, AG Elliott, M Baker, S Braese, C Brown, F Chen, ... Chemical science 11 (10), 2627-2639, 2020 | 443 | 2020 |
Metals to combat antimicrobial resistance A Frei, AD Verderosa, AG Elliott, J Zuegg, MAT Blaskovich Nature Reviews Chemistry 7 (3), 202-224, 2023 | 365 | 2023 |
Contribution of amphipathicity and hydrophobicity to the antimicrobial activity and cytotoxicity of β-hairpin peptides IA Edwards, AG Elliott, AM Kavanagh, J Zuegg, MAT Blaskovich, ... ACS infectious diseases 2 (6), 442-450, 2016 | 265 | 2016 |
Helping chemists discover new antibiotics MAT Blaskovich, J Zuegg, AG Elliott, MA Cooper ACS infectious diseases 1 (7), 285-287, 2015 | 224 | 2015 |
The antimicrobial potential of cannabidiol MAT Blaskovich, AM Kavanagh, AG Elliott, B Zhang, S Ramu, M Amado, ... Communications biology 4 (1), 1-18, 2021 | 221 | 2021 |
Identification of active-site residues of the pro-metastatic endoglycosidase heparanase MD Hulett, JR Hornby, SJ Ohms, J Zuegg, C Freeman, JE Gready, ... Biochemistry 39 (51), 15659-15667, 2000 | 202 | 2000 |
Imperfect coordination chemistry facilitates metal ion release in the Psa permease RM Couñago, MP Ween, SL Begg, M Bajaj, J Zuegg, ML O'mara, ... Nature chemical biology 10 (1), 35-41, 2014 | 159 | 2014 |
An amphipathic peptide with antibiotic activity against multidrug-resistant Gram-negative bacteria AG Elliott, JX Huang, S Neve, J Zuegg, IA Edwards, AK Cain, CJ Boinett, ... Nature communications 11 (1), 3184, 2020 | 150 | 2020 |
Protein-inspired antibiotics active against vancomycin-and daptomycin-resistant bacteria MAT Blaskovich, KA Hansford, Y Gong, MS Butler, C Muldoon, JX Huang, ... Nature communications 9 (1), 22, 2018 | 139 | 2018 |
Molecular diversity through sugar scaffolds GT Le, G Abbenante, B Becker, M Grathwohl, J Halliday, G Tometzki, ... Drug Discovery Today 8 (15), 701-709, 2003 | 121 | 2003 |
Molecular dynamics simulations of human prion protein: importance of correct treatment of electrostatic interactions J Zuegg, JE Gready Biochemistry 38 (42), 13862-13876, 1999 | 121 | 1999 |
A probabilistic measure for alignment-free sequence comparison TD Pham, J Zuegg Bioinformatics 20 (18), 3455-3461, 2004 | 120 | 2004 |
Molecular dynamics simulation of human prion protein including both N-linked oligosaccharides and the GPI anchor J Zuegg, JE Gready Glycobiology 10 (10), 959-974, 2000 | 116 | 2000 |
Three-dimensional structures of enzyme–substrate complexes of the hydroxynitrile lyase from Hevea brasiliensis J Zuegg, K Gruber, M Gugganig, UG Wagner, C Kratky Protein Science 8 (10), 1990-2000, 1999 | 86 | 1999 |
Molecular reasons for lipase-sensitivity against acetaldehyde HK Weber, J Zuegg, K Faber, J Pleissb Journal of Molecular Catalysis B: Enzymatic 3 (1-4), 131-138, 1997 | 70 | 1997 |
G. Dowson, C.; Dujardin, G A Frei, J Zuegg, AG Elliott, M Baker, S Braese, C Brown, F Chen Jung, n, 2627-2639, 2020 | 67 | 2020 |
Vancomycin: ligand recognition, dimerization and super‐complex formation ZG Jia, ML O'Mara, J Zuegg, MA Cooper, AE Mark The FEBS journal 280 (5), 1294-1307, 2013 | 65 | 2013 |
Drug-likeness and increased hydrophobicity of commercially available compound libraries for drug screening J Zuegg, M A. Cooper Current topics in medicinal chemistry 12 (14), 1500-1513, 2012 | 65 | 2012 |
Selectivity of lipases: Conformational analysis of suggested intermediates in ester hydrolysis of chiral primary and secondary alcohols J Zuegg, H Hönig, JD Schrag, M Cygler Journal of Molecular Catalysis B: Enzymatic 3 (1-4), 83-98, 1997 | 65 | 1997 |
Metronidazole-triazole conjugates: activity against Clostridium difficile and parasites AM Jarrad, T Karoli, A Debnath, CY Tay, JX Huang, G Kaeslin, AG Elliott, ... European Journal of Medicinal Chemistry 101, 96-102, 2015 | 60 | 2015 |