| Biosynthetic manipulation of tryptophan in bacteria: pathways and mechanisms LM Alkhalaf, KS Ryan Chemistry & biology 22 (3), 317-328, 2015 | 194 | 2015 |
| Rieske non-heme iron-dependent oxygenases catalyse diverse reactions in natural product biosynthesis C Perry, ELC De los Santos, LM Alkhalaf, GL Challis Natural Product Reports 35 (7), 622-632, 2018 | 86 | 2018 |
| Catalytic mechanism of aromatic nitration by cytochrome P450 TxtE: involvement of a ferric-peroxynitrite intermediate S Louka, SM Barry, DJ Heyes, MQE Mubarak, HS Ali, LM Alkhalaf, ... Journal of the American Chemical Society 142 (37), 15764-15779, 2020 | 81 | 2020 |
| In vitro reconstitution of indolmycin biosynthesis reveals the molecular basis of oxazolinone assembly YL Du, LM Alkhalaf, KS Ryan Proceedings of the National Academy of Sciences 112 (9), 2717-2722, 2015 | 61 | 2015 |
| A pyridoxal phosphate–dependent enzyme that oxidizes an unactivated carbon-carbon bond YL Du, R Singh, LM Alkhalaf, E Kuatsjah, HY He, LD Eltis, KS Ryan Nature Chemical Biology 12 (3), 194-199, 2016 | 49 | 2016 |
| Desferrioxamine biosynthesis: diverse hydroxamate assembly by substrate-tolerant acyl transferase DesC JL Ronan, N Kadi, SA McMahon, JH Naismith, LM Alkhalaf, GL Challis Philosophical Transactions of the Royal Society B: Biological Sciences 373 …, 2018 | 42 | 2018 |
| Mechanistic insights into class B radical-S-adenosylmethionine methylases: ubiquitous tailoring enzymes in natural product biosynthesis S Zhou, LM Alkhalaf, EL de Los Santos, GL Challis Current opinion in chemical biology 35, 73-79, 2016 | 41 | 2016 |
| Binding of distinct substrate conformations enables hydroxylation of remote sites in thaxtomin D by cytochrome P450 TxtC LM Alkhalaf, SM Barry, D Rea, A Gallo, D Griffiths, JR Lewandowski, ... Journal of the American Chemical Society 141 (1), 216-222, 2018 | 38 | 2018 |
| Molecular basis for control of antibiotic production by a bacterial hormone S Zhou, H Bhukya, N Malet, PJ Harrison, D Rea, MJ Belousoff, ... Nature 590 (7846), 463-467, 2021 | 28 | 2021 |
| Expanding the substrate scope of nitrating cytochrome P450 TxtE by active site engineering of a reductase fusion R Saroay, GD Roiban, LM Alkhalaf, GL Challis ChemBioChem 22 (13), 2262-2265, 2021 | 13 | 2021 |
| Parallelized gene cluster editing illuminates mechanisms of epoxyketone proteasome inhibitor biosynthesis C Huang, D Zabala, ELC De Los Santos, L Song, C Corre, LM Alkhalaf, ... Nucleic Acids Research 51 (3), 1488-1499, 2023 | 7 | 2023 |
| Synthetic biology approaches to new bisindoles LM Alkhalaf, YL Du, KS Ryan Methods in Enzymology 575, 21-37, 2016 | 6 | 2016 |
| Discovery and Biosynthesis of Persiathiacins: Unusual Polyglycosylated Thiopeptides Active Against Multidrug Resistant Tuberculosis Y Dashti, F Mohammadipanah, Y Zhang, PM Cerqueira Diaz, A Vocat, ... ACS infectious diseases 10 (9), 3378-3391, 2024 | 5 | 2024 |
| Antibiotic Skeletal Diversification via Differential Enoylreductase Recruitment and Module Iteration in trans-Acyltransferase Polyketide Synthases X Jian, F Pang, C Hobson, M Jenner, LM Alkhalaf, GL Challis Journal of the American Chemical Society 146 (9), 6114-6124, 2024 | 1 | 2024 |
| Structural basis for control of antibiotic production by bacterial hormones S Zhou, H Bhukya, N Malet, PJ Harrison, D Rea, MJ Belousoff, ... bioRxiv, 2020.05. 02.073981, 2020 | 1 | 2020 |
| A gatekeeper enzyme in the biosynthesis of indolmycin YL Du, LM Alkhalaf, KS Ryan Planta Medica 81 (11), PN2, 2015 | 1 | 2015 |
| PARAS: high-accuracy machine-learning of substrate specificities in nonribosomal peptide synthetases BR Terlouw, C Huang, D Meijer, JDD Cediel-Becerra, ML Rothe, ... bioRxiv, 2025.01. 08.631717, 2025 | | 2025 |
| Thoughts for the future LM Alkhalaf, C Arrowsmith, EP Balskus, G Bergamini, R Bhandari, ... nature chemical biology 21 (1), 6-15, 2025 | | 2025 |
| Native ESI-MS and Collision-Induced Unfolding (CIU) of the Complex between Bacterial Elongation Factor-Tu and the Antibiotic Enacyloxin IIa C Baines, J Sargeant, CD Fage, H Pugh, LM Alkhalaf, GL Challis, ... Journal of the American Society for Mass Spectrometry 35 (7), 1490-1496, 2024 | | 2024 |
| Discovery and Biosynthesis of Persiathiacins Y Dashti, F Mohammadipanah, Y Zhang, PM Cerqueira Diaz, A Vocat, ... | | 2024 |
