| Artificial metalloenzymes: reaction scope and optimization strategies F Schwizer, Y Okamoto, T Heinisch, Y Gu, MM Pellizzoni, V Lebrun, ... Chemical reviews 118 (1), 142-231, 2018 | 758 | 2018 |
| Directed evolution of artificial metalloenzymes for in vivo metathesis M Jeschek, R Reuter, T Heinisch, C Trindler, J Klehr, S Panke, TR Ward Nature 537 (7622), 661-665, 2016 | 471 | 2016 |
| Artificial metalloenzymes based on the biotin–streptavidin technology: challenges and opportunities T Heinisch, TR Ward Accounts of chemical research 49 (9), 1711-1721, 2016 | 205 | 2016 |
| Artificial transfer hydrogenases for the enantioselective reduction of cyclic imines M Dürrenberger, T Heinisch, Y Wilson, T Rossel, E Nogueira, L Knörr, ... Angewandte Chemie International Edition 50 (13), 3026-3029, 2011 | 190 | 2011 |
| Design strategies for the creation of artificial metalloenzymes T Heinisch, TR Ward Current opinion in chemical biology 14 (2), 184-199, 2010 | 153 | 2010 |
| A cell-penetrating artificial metalloenzyme regulates a gene switch in a designer mammalian cell Y Okamoto, R Kojima, F Schwizer, E Bartolami, T Heinisch, S Matile, ... Nature communications 9 (1), 1943, 2018 | 126 | 2018 |
| A dual anchoring strategy for the localization and activation of artificial metalloenzymes based on the biotin–streptavidin technology JM Zimbron, T Heinisch, M Schmid, D Hamels, ES Nogueira, T Schirmer, ... Journal of the American Chemical Society 135 (14), 5384-5388, 2013 | 119 | 2013 |
| Improving the catalytic performance of an artificial metalloenzyme by computational design T Heinisch, M Pellizzoni, M Dürrenberger, CE Tinberg, V Köhler, ... Journal of the American Chemical Society 137 (32), 10414-10419, 2015 | 107 | 2015 |
| E. coli surface display of streptavidin for directed evolution of an allylic deallylase T Heinisch, F Schwizer, B Garabedian, E Csibra, M Jeschek, ... Chemical science 9 (24), 5383-5388, 2018 | 96 | 2018 |
| OsO4⋅ Streptavidin: A Tunable Hybrid Catalyst for the Enantioselective cis‐Dihydroxylation of Olefins V Köhler, J Mao, T Heinisch, A Pordea, A Sardo, YM Wilson, L Knörr, ... Angewandte Chemie-International Edition 50 (46), 10863, 2011 | 94 | 2011 |
| Human carbonic anhydrase II as host protein for the creation of artificial metalloenzymes: the asymmetric transfer hydrogenation of imines FW Monnard, ES Nogueira, T Heinisch, T Schirmer, TR Ward Chemical Science 4 (8), 3269-3274, 2013 | 91 | 2013 |
| Human carbonic anhydrase II as a host for piano-stool complexes bearing a sulfonamide anchor FW Monnard, T Heinisch, ES Nogueira, T Schirmer, TR Ward Chemical Communications 47 (29), 8238-8240, 2011 | 91 | 2011 |
| Structural, kinetic, and docking studies of artificial imine reductases based on biotin–streptavidin technology: an induced lock-and-key hypothesis VM Robles, M Dürrenberger, T Heinisch, A Lledós, T Schirmer, TR Ward, ... Journal of the American Chemical Society 136 (44), 15676-15683, 2014 | 88 | 2014 |
| Peroxide activation regulated by hydrogen bonds within artificial Cu proteins SI Mann, T Heinisch, TR Ward, AS Borovik Journal of the American Chemical Society 139 (48), 17289-17292, 2017 | 62 | 2017 |
| Structural, functional, and spectroscopic characterization of the substrate scope of the novel nitrating cytochrome P450 TxtE SC Dodani, JKB Cahn, T Heinisch, S Brinkmann‐Chen, JA McIntosh, ... ChemBioChem 15 (15), 2259-2267, 2014 | 59 | 2014 |
| Radical biocatalysis: Using non-natural single electron transfer mechanisms to access new enzymatic functions TK Hyster Synlett 31 (03), 248-254, 2020 | 49 | 2020 |
| Fluorescence-Based Assay for the Optimization of the Activity of Artificial Transfer Hydrogenase within a Biocompatible Compartment. T Heinisch, K Langowska, P Tanner, JL Reymond, W Meier, C Palivan, ... ChemCatChem 5 (3), 2013 | 42 | 2013 |
| Ferritin encapsulation of artificial metalloenzymes: engineering a tertiary coordination sphere for an artificial transfer hydrogenase M Hestericová, T Heinisch, M Lenz, TR Ward Dalton Transactions 47 (32), 10837-10841, 2018 | 36 | 2018 |
| Modular artificial cupredoxins SI Mann, T Heinisch, AC Weitz, MP Hendrich, TR Ward, AS Borovik Journal of the American Chemical Society 138 (29), 9073-9076, 2016 | 32 | 2016 |
| Latest developments in metalloenzyme design and repurposing T Heinisch, TR Ward European Journal of Inorganic Chemistry 2015 (21), 3406-3418, 2015 | 24 | 2015 |
