Prebiotically plausible “patching” of RNA backbone cleavage through a 3′–5′ pyrophosphate linkage TH Wright, C Giurgiu, W Zhang, A Radakovic, DK O’Flaherty, L Zhou, ... Journal of the American Chemical Society 141 (45), 18104-18112, 2019 | 22 | 2019 |
Vinblastine 20′ amides: synthetic analogues that maintain or improve potency and simultaneously overcome Pgp-derived efflux and resistance JC Lukesh III, DW Carney, H Dong, RM Cross, V Shukla, KK Duncan, ... Journal of medicinal chemistry 60 (17), 7591-7604, 2017 | 21 | 2017 |
Nonenzymatic assembly of active chimeric ribozymes from aminoacylated RNA oligonucleotides A Radakovic, S DasGupta, TH Wright, HRM Aitken, JW Szostak Proceedings of the National Academy of Sciences 119 (7), e2116840119, 2022 | 19 | 2022 |
A potential role for aminoacylation in primordial RNA copying chemistry A Radakovic, TH Wright, VS Lelyveld, JW Szostak Biochemistry 60 (6), 477-488, 2021 | 14 | 2021 |
Thermodynamics and kinetics of DNA and RNA dinucleotide hybridization to gaps and overhangs B Ashwood, MS Jones, A Radakovic, S Khanna, Y Lee, JR Sachleben, ... Biophysical Journal 122 (16), 3323-3339, 2023 | 13 | 2023 |
Key analogs of a uniquely potent synthetic vinblastine that contain modifications of the C20′ ethyl substituent O Allemann, RM Cross, MM Brütsch, A Radakovic, DL Boger Bioorganic & medicinal chemistry letters 27 (14), 3055-3059, 2017 | 12 | 2017 |
Ultra-potent vinblastine analogues improve on-target activity of the parent microtubulin-targeting compound A Radakovic, DL Boger Bioorganic & medicinal chemistry letters 29 (11), 1370-1374, 2019 | 9 | 2019 |
High expression of class III β-tubulin has no impact on functional cancer cell growth inhibition of a series of key vinblastine analogs A Radakovic, DL Boger Bioorganic & medicinal chemistry letters 28 (5), 863-865, 2018 | 9 | 2018 |
Small-molecule organocatalysis facilitates in situ nucleotide activation and RNA copying HRM Aitken, TH Wright, A Radakovic, JW Szostak Journal of the American Chemical Society 145 (29), 16142-16149, 2023 | 8 | 2023 |
Did the exposure of coacervate droplets to rain make them the first stable protocells? A Agrawal, A Radakovic, A Vonteddu, S Rizvi, VN Huynh, JF Douglas, ... Science Advances 10 (34), eadn9657, 2024 | 7 | 2024 |
A potential role for RNA aminoacylation prior to its role in peptide synthesis A Radakovic, A Lewicka, M Todisco, HRM Aitken, Z Weiss, S Kim, ... Proceedings of the National Academy of Sciences 121 (35), e2410206121, 2024 | 5 | 2024 |
Discovery of Thioether-Cyclized Macrocyclic Covalent Inhibitors by mRNA Display T Lan, C Peng, X Yao, RST Chan, T Wei, A Rupanya, A Radakovic, ... Journal of the American Chemical Society 146 (34), 24053-24060, 2024 | 3 | 2024 |
RNA complexes with nicks and gaps: thermodynamic and kinetic effects of coaxial stacking and dangling ends M Todisco, A Radakovic, JW Szostak Journal of the American Chemical Society 146 (26), 18083-18094, 2024 | 1 | 2024 |
Structure-guided aminoacylation and assembly of chimeric RNAs A Radakovic, A Lewicka, M Todisco, HRM Aitken, Z Weiss, S Kim, ... BioRxiv, 2024.03. 02.583109, 2024 | 1 | 2024 |
Direct monitoring of the thermodynamics and kinetics of DNA and RNA dinucleotide dehybridization from gaps and overhangs B Ashwood, MS Jones, A Radakovic, S Khanna, Y Lee, JR Sachleben, ... bioRxiv, 2023 | 1 | 2023 |
Insights into Free Drug Release from Efficacious N-Acyl O-Aminophenol Duocarmycin Prodrugs N Chakraborty, J Momirov, A Radakovic, S Chatterjee, AM Kirchhoff, ... ACS Chemical Biology, 2025 | | 2025 |
Selective Nonenzymatic Formation of Biologically Common RNA Hairpins LF Wu, J Zhang, R Cornwell‐Arquitt, DA Hendrix, A Radakovic, ... Angewandte Chemie 137 (5), e202417370, 2025 | | 2025 |
Stereoselectivity of Aminoacyl-RNA Loop-closing Ligation S Kim, M Todisco, A Radakovic, JW Szostak bioRxiv, 2024.11. 26.625528, 2024 | | 2024 |
Primordial role for RNA aminoacylation in the assembly of structured and functional chimeric RNAs A Radakovic | | 2024 |
Nanopore sequencing of intact aminoacylated tRNAs LK White, A Radakovic, MP Sajek, K Dobson, KA Riemondy, S Del Pozo, ... bioRxiv, 2024.11. 18.623114, 2024 | | 2024 |