Prati
Aleksandar Radakovic
Aleksandar Radakovic
Chicago Fellow, University of Chicago
Potvrđena adresa e-pošte na uchicago.edu
Naslov
Citirano
Citirano
Godina
Prebiotically plausible “patching” of RNA backbone cleavage through a 3′–5′ pyrophosphate linkage
TH Wright, C Giurgiu, W Zhang, A Radakovic, DK O’Flaherty, L Zhou, ...
Journal of the American Chemical Society 141 (45), 18104-18112, 2019
222019
Vinblastine 20′ amides: synthetic analogues that maintain or improve potency and simultaneously overcome Pgp-derived efflux and resistance
JC Lukesh III, DW Carney, H Dong, RM Cross, V Shukla, KK Duncan, ...
Journal of medicinal chemistry 60 (17), 7591-7604, 2017
212017
Nonenzymatic assembly of active chimeric ribozymes from aminoacylated RNA oligonucleotides
A Radakovic, S DasGupta, TH Wright, HRM Aitken, JW Szostak
Proceedings of the National Academy of Sciences 119 (7), e2116840119, 2022
192022
A potential role for aminoacylation in primordial RNA copying chemistry
A Radakovic, TH Wright, VS Lelyveld, JW Szostak
Biochemistry 60 (6), 477-488, 2021
142021
Thermodynamics and kinetics of DNA and RNA dinucleotide hybridization to gaps and overhangs
B Ashwood, MS Jones, A Radakovic, S Khanna, Y Lee, JR Sachleben, ...
Biophysical Journal 122 (16), 3323-3339, 2023
132023
Key analogs of a uniquely potent synthetic vinblastine that contain modifications of the C20′ ethyl substituent
O Allemann, RM Cross, MM Brütsch, A Radakovic, DL Boger
Bioorganic & medicinal chemistry letters 27 (14), 3055-3059, 2017
122017
Ultra-potent vinblastine analogues improve on-target activity of the parent microtubulin-targeting compound
A Radakovic, DL Boger
Bioorganic & medicinal chemistry letters 29 (11), 1370-1374, 2019
92019
High expression of class III β-tubulin has no impact on functional cancer cell growth inhibition of a series of key vinblastine analogs
A Radakovic, DL Boger
Bioorganic & medicinal chemistry letters 28 (5), 863-865, 2018
92018
Small-molecule organocatalysis facilitates in situ nucleotide activation and RNA copying
HRM Aitken, TH Wright, A Radakovic, JW Szostak
Journal of the American Chemical Society 145 (29), 16142-16149, 2023
82023
Did the exposure of coacervate droplets to rain make them the first stable protocells?
A Agrawal, A Radakovic, A Vonteddu, S Rizvi, VN Huynh, JF Douglas, ...
Science Advances 10 (34), eadn9657, 2024
72024
A potential role for RNA aminoacylation prior to its role in peptide synthesis
A Radakovic, A Lewicka, M Todisco, HRM Aitken, Z Weiss, S Kim, ...
Proceedings of the National Academy of Sciences 121 (35), e2410206121, 2024
52024
Discovery of Thioether-Cyclized Macrocyclic Covalent Inhibitors by mRNA Display
T Lan, C Peng, X Yao, RST Chan, T Wei, A Rupanya, A Radakovic, ...
Journal of the American Chemical Society 146 (34), 24053-24060, 2024
32024
RNA complexes with nicks and gaps: thermodynamic and kinetic effects of coaxial stacking and dangling ends
M Todisco, A Radakovic, JW Szostak
Journal of the American Chemical Society 146 (26), 18083-18094, 2024
12024
Structure-guided aminoacylation and assembly of chimeric RNAs
A Radakovic, A Lewicka, M Todisco, HRM Aitken, Z Weiss, S Kim, ...
BioRxiv, 2024.03. 02.583109, 2024
12024
Direct monitoring of the thermodynamics and kinetics of DNA and RNA dinucleotide dehybridization from gaps and overhangs
B Ashwood, MS Jones, A Radakovic, S Khanna, Y Lee, JR Sachleben, ...
bioRxiv, 2023
12023
Insights into Free Drug Release from Efficacious N-Acyl O-Aminophenol Duocarmycin Prodrugs
N Chakraborty, J Momirov, A Radakovic, S Chatterjee, AM Kirchhoff, ...
ACS Chemical Biology, 2025
2025
Selective Nonenzymatic Formation of Biologically Common RNA Hairpins
LF Wu, J Zhang, R Cornwell‐Arquitt, DA Hendrix, A Radakovic, ...
Angewandte Chemie 137 (5), e202417370, 2025
2025
Stereoselectivity of Aminoacyl-RNA Loop-closing Ligation
S Kim, M Todisco, A Radakovic, JW Szostak
bioRxiv, 2024.11. 26.625528, 2024
2024
Primordial role for RNA aminoacylation in the assembly of structured and functional chimeric RNAs
A Radakovic
2024
Nanopore sequencing of intact aminoacylated tRNAs
LK White, A Radakovic, MP Sajek, K Dobson, KA Riemondy, S Del Pozo, ...
bioRxiv, 2024.11. 18.623114, 2024
2024
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